Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis

L. LANGMEAD

Aliment Pharmacol Ther 2004; 19: 739–747

SUMMARY
Background: The herbal preparation, aloe vera, has been claimed to have anti-inflammatory effects and, despite a lack of evidence of its therapeutic efficacy, is widely used by patients with inflammatory bowel disease.

Conclusion: Oral aloe vera taken for 4 weeks produced a clinical response more often than placebo; it also reduced the histological disease activity and appeared to be safe. Further evaluation of the therapeutic potential of aloe vera gel in inflammatory bowel disease is needed.

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