A double blind randomized controlled pilot trial
Complementary Therapies in Medicine, 02/25/2014 Clinical Article
van Tilburg MAL, et al. – Ginger is one of the most commonly used herbal medicines for irritable bowel syndrome (IBS) but no data exists about its effectiveness. This double blind randomized controlled pilot study suggests ginger is well tolerated but did not perform better than placebo. Larger trials are needed before any definitive conclusions can be drawn.
Methods
- Double blind randomized controlled trial.
- University of North Carolina, Chapel Hill, North Carolina, USA.
- Forty-five IBS patients were randomly assigned to three groups: placebo, 1g of ginger, and 2g of ginger daily for 28 days.
- The IBS severity scale (IBS-SS) was administered, as well as adequate relief of symptoms scale. A responder was defined as having at least 25% reduction in IBS-SS post-treatment.
Results
- There were 57.1% responders to placebo, 46.7% to 1g and 33.3% to 2g of ginger.
- Adequate relief was reported by 53.3% on placebo and 53.3% in both ginger groups combined.
- Side effects were mild and reported by 35.7% in the placebo and 16.7% in the ginger groups.
Is ginger effective for the treatment of irritable bowel syndrome? A double blind randomized controlled pilot trial
Miranda A.L. van Tilburg
Complementary Therapies in Medicine
Volume 22, Issue 1 , Pages 17-20, February 2014
Summary
Objectives
Ginger is one of the most commonly used herbal medicines for irritable bowel syndrome (IBS) but no data exists about its effectiveness.
Design
Double blind randomized controlled trial.
Setting
University of North Carolina, Chapel Hill, North Carolina, USA.
Intervention
Forty-five IBS patients were randomly assigned to three groups: placebo, 1g of ginger, and 2g of ginger daily for 28 days.
Main outcome measures
The IBS severity scale (IBS-SS) was administered, as well as adequate relief of symptoms scale. A responder was defined as having at least 25% reduction in IBS-SS post-treatment.
Results
There were 57.1% responders to placebo, 46.7% to 1g and 33.3% to 2g of ginger. Adequate relief was reported by 53.3% on placebo and 53.3% in both ginger groups combined. Side effects were mild and reported by 35.7% in the placebo and 16.7% in the ginger groups.
Conclusions
This double blind randomized controlled pilot study suggests ginger is well tolerated but did not perform better than placebo. Larger trials are needed before any definitive conclusions can be drawn.