Your Medical Detective
Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S.

If you are one of the 33 million people suffering with a sinus infection, then this special report will be of great interest. Not a day goes by in my office that I don’t see a patient who is complaining of a runny nose, facial pain, “sinus” headache.. you know the pain…it is simply just “miserable”..

This report is a brief summary of a patient I recently treated with chronic sinusitis.

The patient’s name is Marilyn. She was first seen in my office in April of this year. Marilyn is a 38 year old mother of two who happens to work as a part-time legal secretary for a prominent personal injury law firm.

Marilyn’s sinus problems go back over four years. She was first seen by her primary medical physician, then referred to an allergist, then referred to an internist and actually consulted with a chiropractor hoping just maybe.. chiropractic adjustments would rid her of her chronic sinus suffering.

Well.. needless to say.. Marilyn’s problem did not improve. If anything, she got worse (excuse the English slang). As typical for many sinus suffers, Marilyn was prescribed clarithromycin, an antibiotics, pseudoephedrine and phenylpropanolamine, both oral decongestants, phenylephrine hydrochloride, a nasal spray decongestant, anti-histamines, and finally a short course of steroids..

Nothing worked…..”long term”.

Marilyn was, to say the least, extremely frustrated and to be quite honest very reluctant to see me. She figured after four years of trying “the best that medicine has to offer”, that she would simply have to settle for the fact that sinus pain will be a permanent part of her life.

On Marilyn’s first visit, I could sense that she had “mixed” feelings being in my office. On one hand, she was “fed up” having to go day after day with a runny nose and all the terrible symptoms and on the other hand, she pretty much was resigned to “make due” with her present circumstances.. Overall, deep down, Marilyn was really hoping I could help, but on the surface, I could tell she was not expecting anything much more in the way of relief..

Prior to seeing Marilyn, as with all patients, I requested a copy of all her medical records and saw that she had been seen by three different physicians. As is noted above, Marilyn was prescribed various medications and also told to avoid cat dander, pollen, dust and a number of common trees. Obviously, the impossible was asked of her.. If only she was living in a “bubble”.. just maybe she could avoid such things..(Sorry for my sarcasm).

As Marilyn “poured” her heart out, she explained how disappointed she was having to go year after year with these symptoms. She kept telling me that she realized that there were people with worse problems then hers and felt silly being in my office.. I re-assured her that her problem… although not life-threatening deserved the same attention as any other condition.. I further explained that any condition that interferes with your life.. your ability to be productive, simply anything that prevents you from enjoying life is worthy of my or any physician’s time..

After carefully reviewing Marilyn’s case, I decided to order an IgG Food Sensitivity Assay and an Airborne IgE Assay.

Let me explain….

Marilyn was tested approximately 2 years ago by an allergist using the traditional “skin prick or scratch test”.. This test will only detect an IgE reaction.. meaning an “immediate” reaction and is commonly referred to as Type I immune reaction.

An IgG Food Sensitivity Assay is commonly referred to as a Type 3 Delayed-Onset Immune Reaction…

The IgG Food Allergy Test and the IgE Airborne Test both required “one” vial of blood and were sent off to Immuno Labs. The turn-around time is usually 10 working days.

When I received the results, I was surprised to discover that Marilyn’s IgG food allergy test DID NOT reveal any allergic reactions to a specific food, however, what was discovered on her IgE airborne allergy test was to be the “answer” to her four year battle with sinusitis.

As mentioned a few moments ago, Marilyn was tested using the traditional skin prick method for an IgE allergen and found to be reactive to cat dander, pollen and specific tree. When I reviewed the results of the test I ordered, Marilyn was indeed reactive to cat dander and weed pollen, however, one allergen was totally overlooked and was “off the charts”.. Allergic reactions are graded 0, +1, +2, +3, +4 .. with 0 indicating no reaction and +4 indicating a severe reaction. Her test revealed a +4 Alternaria reaction.

Now.. I can here you saying, what in the world is an Alternaria reaction.. Well.. let me quote a few lines from the Mayo Clinic article written by Ronald Lawrence M.D.

Wow! Isn’t that interesting?

I remember reviewing the results with Marilyn and going over all the medical abstracts supporting the relationship between chronic sinusitis and fungal infections. Marilyn looked at me with a “blank” stare and asked “why didn’t the three doctors she saw over the last four years ever check her for fungal infections?” I re-assured her that her doctors were doing what they had been trained to do and in no way wanted her to suffer over these last four years.

Based on this new information, the following were the “exact” treatments I recommended:

a) I personally called her primary physician and reviewed Marilyn’s findings and asked if he would prescribe an anti-fungal medication. Of course, he was reluctant at first. However, after he reviewed the medical support documentation (see below), he was willing to do a trial of Fluconazole.

b) I recommended following the Fluconazole with a natural anti-microbial product for two weeks.

c) I had Marilyn do a thorough check of her home and see if she could find any mold build-up (which she did on her bedroom window baseboard)

d) I suggested that Marilyn purchase a “micro” hepa filter to use in her bedroom.

Marilyn’s Results:

One week following her first prescription with Fluconazole, Marilyn was 50% better. Three weeks after starting the natural anti-microbial and purchasing a “micro” hepa filter, Marilyn admitted to feeling 90% better. Just recently, I spoke to Marilyn and she has not had problem with her sinuses for over three months. She was ecstatic and couldn’t contain her enthusiasm..Matter of fact, her physician expressed an interest in learning more about functional medicine and wanted to have lunch with me..

Dr. Grisanti’s Comments:

I am glad to see that Marilyn has done so well and that we finally found the reason for her chronic sinus problems. I want to be certain that everyone reading this DOES NOT phone their doctor and ask for a prescription for Fluconazole or any other anti-fungal medication. Although it is entirely possible that you just might be suffering with a Alternaria fungal infection, I wouldn’t attempt to self-treat.

You see, I see many patients with different health challenges and understand that their is NO “one treatment fits all” solution to the array of health conditions. You have heard me say that “I treat the patient not the condition.”

Unlike the drug ads on television or any major magazine that promote a drug for XYZ disease, my approach is very logical. I look for the underlying “cause(s)” of a patients problem. Remember this… and remember it well..I can have three patients suffering with sinus problems and each one of these patients may have a different reason for their sinus condition. One may be suffering with an Alternaria fungal infection, another from a food allergy and yet another from poor detoxification function (yes I did say detoxification).. Each of these patients would require completely different treatments..

Ask yourself this question.. What would happen if I treat the patient suffering with a food allergy-related sinus problem with an anti-fungal medication? Yes.. you are right … nothing.. the patient would simply not improve…

Remember, find the cause.. match it with the correct treatment and many times the patient experiences an amazing improvement.. Please understand that finding the cause(s) of a patient’s health challenge is not always simple.. but many times is found.. Remember, if you suffer with sinus problems or any health challenge, I want to challenge you to see if your physician is looking for the cause or simply “masking” the symptoms with the most popular advertised drug on the market. Think about it..

REFERENCES:

Cody DT 2nd, McCaffrey TV, Roberts G, Kern EB. Effects of Aspergillus fumigatus and Alternaria alternata on human ciliated epithelium in vitro. Laryngoscope. 1997 Nov;107(11 Pt 1):1511-4.

Cody DT 2nd, Neel HB 3rd, Ferreiro JA, Roberts GD. Allergic fungal sinusitis: the Mayo Clinic experience.
Laryngoscope. 1994 Sep;104(9):1074-9.

Vennewald I, Henker M, Klemm E, Seebacher C. Fungal colonization of the paranasal sinuses. Mycoses. 1999;42 (Suppl 2):33-6.

Andes D, Proctor R, Bush RK, Pasic TR Report of successful prolonged antifungal therapy for refractory allergic fungal sinusitis. Clin Infect Dis. 2000 Jul;31(1):202-4.

Karpovich-Tate N, Dewey FM, Smith EJ, Lund VJ, Gurr PA, Gurr SJ. Detection of fungi in sinus fluid of patients with allergic fungal rhinosinusitis. Acta Otolaryngol. 2000 Mar;120(2):296-302.

Catten MD, Murr AH, Goldstein JA, Mhatre AN, Lalwani AK. Detection of fungi in the nasal mucosa using polymerase chain reaction. Laryngoscope. 2001 Mar;111(3):399-403.

Full Story

The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Grisanti and his community. Dr. Grisanti encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Visit www.FunctionalMedicineUniversity.com to find practitioners thoroughly trained in functional medicine. Look for practitioners who have successfully completed the Functional Medicine University’s Certification Program (CFMP).

This content may be copied in full, with copyright, contact, creation and information intact, without specific permission, when used only in a not-for-profit format. If any other use is desired, permission in writing from Dr. Grisanti is required.