Tay J
Diabetes Care. 2014 Jul 28. pii: DC_140845. [Epub ahead of print]
Abstract
OBJECTIVE:
To comprehensively compare the effects of a very low carbohydrate, high unsaturated/low saturated fat diet (LC) to a high-unrefined carbohydrate, low fat diet (HC) on glycemic control and cardiovascular disease (CVD) risk factors in type 2 diabetes (T2DM).
RESEARCH DESIGN AND METHODS:
Obese adults (n = 115, BMI 34.4 ± 4.2 kg/m2, age 58 ± 7 years) with T2DM were randomized to a hypocaloric LC diet (14% carbohydrate [7.8% (62 mmol/mol) and HDL-C
CONCLUSIONS:
Both diets achieved substantial improvements for several clinical glycemic control and CVD risk markers. These improvements and reductions in GV and antiglycemic medication requirements were greatest with the LC compared with HC. This suggests an LC diet with low saturated fat may be an effective dietary approach for T2DM management if effects are sustained beyond 24 weeks.