Drinking Sweet Beverages and Type 2 Diabetes: Beyond Obesity

Expert Opinion / Commentary · August 04, 2015
Written by Wahida Karmally DrPH, RD, CDE, CLS, FNLA

Sugar is on the FDA “generally recognized as safe” list despite the growing body of evidence that sugar-sweetened beverage (SSB) consumption is detrimental to health and has been associated with increased risk of cardiovascular disease mortality,1 hypertension,2,3 liver lipogenesis,4 type 2 diabetes (T2DM),5-7 and kidney disease.8 SSBs include a variety of drinks, including soft drinks, fruit drinks, sweetened flavored milk, energy drinks, and vitamin water drinks. These have gained popularity globally.

O’Conner and colleagues, in an article published in May in Diabetologia9 add an important dimension to the health effects of SSBs relevant to the entire population. They concluded that, independently of adiposity, SSBs, including sweetened milk beverages, were associated with increased risk for T2DM. The study estimated the population impact of consuming SSB; 3% to 15% of incident diabetes cases might be prevented if consumers decreased sugar intake to a range between 2% and 10% of total energy intake. AHA and WHO have recommendations for sugar that fall within this range.10,11

Strategies to increase awareness of sugar content of SSBs as well as sweetened milk beverages with warning labels are widely debated. Research related to tobacco has shown that warning labels have a positive effect in informing the consumers of risks and prompting behavior change.12 Tackling over-consumption requires multiple policy approaches. Children need parental guidance to help them consume nutrient-dense drinks that are enjoyable.

  1. Yang Q, Zhang Z, Gregg EW, et al. Added sugar intake and cardiovascular diseases mortality among US adults. JAMA Intern Med. 2014;174(4):516-524.
  2. Xi B, Huang Y, Reilly KH, et al. Sugar-sweetened beverages and risk of hypertension and CVD: a dose-response meta-analysis. Br J Nutr. 2015;113(5):709-717.
  3. Sayon-Orea C, Martinez-Gonzalez MA, Gea A, et al. Baseline consumption and changes in sugar-sweetened beverage consumption and the incidence of hypertension: The SUN project [published online November 22, 2014]. Clin Nutr. doi: 10.1016/j.clnu.2014.11.010.
  4. Shimony MK, Schliep KC, Schisterman EF, et al. The relationship between sugar-sweetened beverages and liver enzymes among healthy premenopausal women: a prospective cohort study [published online March 24, 2015]. Eur J Nutr. DOI: 10.1007/s00394-015-0876-3.
  5. Malik VS, Popkin BM, Bray GA, et al. Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care. 2010;33(11):2477-2483.
  6. Greenwood DC, Threapleton DE, Evans CE, et al. Association between sugar-sweetened and artificially sweetened soft drinks and type 2 diabetes: systematic review and dose-response meta-analysis of prospective studies. Br J Nutr. 2014;112(5):725-734.
  7. Wang M, Yu M, Fang L, Hu RY. Association between sugar-sweetened beverages and type 2 diabetes: A meta-analysis. J Diabetes Investig. 2015;6(3):360-366.
  8. Cheungpasitporn W, Thongprayoon C, O’Corragain OA, et al. Associations of sugar-sweetened and artificially sweetened soda with chronic kidney disease: a systematic review and meta-analysis. Nephrology (Carlton). 2014;19(12):791-797.
  9. O’Connor L, Imamura F, Lentjes MA, et al. Prospective associations and population impact of sweet beverage intake and type 2 diabetes, and effects of substitutions with alternative beverages [published online May 6, 2015]. Diabetologia. doi: 10.1007/s00125-015-3572-1
  10. Johnson RK, Appel LJ, Brands M, et al. Dietary sugars intake and cardiovascular health: a scientific statement from the American Heart Association. 2009;120(11):1011-1020.
  11. World Health Organization Technical Staff. Reducing consumption of sugar-sweetened beverages to reduce the risk of unhealthy weight gain in adults. Available at: http://www.who.int/elena/titles/ssbs_adult_weight/en/. Published September 2014. Accessed May 21, 2015.
  12. Hammond, D, Fong GT, Borland R, Cummings KM, McNeill A, Driezen P. Text and graphic warnings on cigarette packages: findings from the international tobacco control four country study. Am J Prev Med. 2007;32(3):202-209.

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