The effects of folate supplementation on glucose metabolism and risk of type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials

Annals of Epidemiology — | February 26, 2018

Zhao JV, et al. – Folate, which reduces homocysteine, is promising for the prevention and treatment of diabetes. Previous meta-analysis of 3 trials suggested folate might lower hemoglobin A1c (HbA1c). In this current updated systematic review and meta-analysis of placebo-controlled randomized trials, a potential benefit of folate on insulin resistance and glycemic control was suggested.

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