Circulation — Malik VS, et al. | May 03, 2019
Among 37,716 men from the Health Professional’s Follow-up Study (HPFS; 1986-2014) and 80,647 women from the Nurses’ Health Study (NHS; 1980-2014), researchers assessed the risk of total and cause-specific mortality in relation to consumption of sugar-sweetened beverages (SSBs) and artificially sweetened beverages (ASBs). Overall, intake of SSBs was positively related to death, primarily through cardiovascular disease (CVD) mortality, and demonstrated a graded link with dose. Among women, investigators found that high intake levels of ASBs were positively associated with total and CVD mortality.
Methods
- The participants were free from chronic diseases at baseline.
- They estimated hazard ratios and 95% CIs using Cox proportional hazards regression.
Results
- They performed 3,415,564 person-years of follow-up, during which time 36,436 deaths (7,896 CVD and 12,380 cancer-related deaths) were reported.
- Findings revealed the association of SSBs intake with a higher risk of total mortality following the adjustment for major diet and lifestyle factors.
- The association was evident for CVD mortality and cancer mortality.
- Only in the highest intake category, was an association of ASBs with total and CVD mortality identified.
- A link between ASBs and mortality was evident in NHS but not in HPFS in cohort-specific analysis.
- There was no association of ASBs with cancer mortality in either cohort.
Read the full article on Circulation
Story Source – site may require registration