Orthopedic Manifestations of Lead Toxicity

Amy L. Meyers, DO; Michael P. Woodbury, DO; Ryan A. Nelson, DO

Orthopedics. https://doi.org/10.3928/01477447-20200415-06
Posted April 23, 2020

Abstract
Given the recent news regarding the water supply in Flint, Michigan, lead toxicity has become an increasingly important topic in health care. Lead toxicity can have a widespread effect on the human body. Because lead has a significant effect on mineralized tissue such as bone, the purpose of this review was to identify and analyze the orthopedic manifestations of lead poisoning. The effects of lead at the cellular level, on the hematopoietic system, in osteoporosis, and in pediatric patients are discussed. Possible treatment options and recommendations for further monitoring are presented. [Orthopedics. 2020;43(x):xx–xx.]

Authors
The authors are from the Orthopedic Surgery Department (ALM), Genesys Regional Medical Center, and the Orthopedic Surgery Department (RAN), Greater Michigan Orthopedics, Grand Blanc, Michigan; and Faith Regional Physician Services (MPW), Norfolk, Nebraska.

The authors have no relevant financial relationships to disclose.

Correspondence should be addressed to: Amy L. Meyers, DO, 8253 Miller Rd, Swartz Creek, MI 48473 ( meyersal12@gmail.com).

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