November 30, 2015 JAMA Psychiatry TAKE-HOME MESSAGE Adults with moderate to severe non-seasonal major depressive disorder (MDD) were randomized to receive light monotherapy, antidepressant monotherapy (fluoxetine hydrochloride), combination light and antidepressant, or placebo for 8 weeks. Light monotherapy and combination therapy were both significantly better than placebo for response and remission, but fluoxetine was not […]