HPA Axis

Measureable changes in the neuro-endocrinal mechanism following spinal manipulation

Med Hypotheses. 2015 Oct 10. pii: S0306-9877(15)00374-6. doi: 10.1016/j.mehy.2015.10.003. [Epub ahead of print] Kovanur Sampath K Abstract The autonomic nervous system and the hypothalamic-pituitary-adrenal axis have been shown to be dysfunctional in a number of chronic pain disorders. Spinal manipulation is a therapeutic technique used by manual therapists, which may have widespread neuro-physiological effects. The […]

Reduced HPA Axis Activity in Chronic Musculoskeletal Pain

Reduced hypothalamic-pituitary-adrenal axis activity in chronic multi-site musculoskeletal pain: partly masked by depressive and anxiety disorders – Full Text BMC Musculoskeletal Disorders, 07/15/2014  Evidence Based Medicine Clinical Article Generaal E, et al. – Studies on hypothalamic–pituitary–adrenal axis (HPA–axis) function amongst patients with chronic pain show equivocal results and well–controlled cohort studies are rare in this […]