Epigenetics

Substantial contribution of extrinsic risk factors to cancer development

Nature 529, 43–47 (07 January 2016) doi:10.1038/nature16166 Received 15 April 2015 Accepted 23 October 2015 Published online 16 December 2015 Song Wu,Scott Powers, Wei Zhu & Yusuf A. Hannun Abstract Recent research has highlighted a strong correlation between tissue-specific cancer risk and the lifetime number of tissue-specific stem-cell divisions. Whether such correlation implies a high […]

Effect of environmental epigenetics on disease, evolution

‘Epigenetics can drive genetics,’ experts say Date: August 3, 2015 Source: Washington State University Summary: Environmental factors are having an underappreciated effect on the course of disease and evolution by prompting genetic mutations through epigenetics, a process by which genes are turned on and off independent of an organism’s DNA sequence. Researchers assert that is […]

Study Suggests Potential Parent–Child Link in Chronic Musculoskeletal Pain

POSTED: AUGUST 18, 2014 Children with parents who have chronic musculoskeletal pain (CMP) are at a higher risk for developing CMP, a new family-linkage study finds. According to researchers from the Norwegian University of Science and Technology in Trondheim, CMP is “among the leading causes of reduced quality of life and disability in Western countries,” […]

Heart-Healthy Lifestyle Changes Also Alter Gene Expression

Marlene Busko March 05, 2014 WINDBER, PA — After a yearlong, intensive diet, exercise, and stress-management program to reduce cardiovascular risk factors, participants who successfully followed the program and lost weight also had positive changes at the molecular level, researchers report[1]. “What’s really new and important about this study is that throughout a year of lifestyle changes, […]

Exercise: Putting Action into Our Epigenome

Denham J,et al. Sports Med. 2013 Oct 27. [Epub ahead of print] Affiliation School of Health Sciences, Federation University Australia, Room 228, Y Building, University Drive, Mt Helen, Ballarat, VIC, 3350, Australia. Abstract Most human phenotypes are influenced by a combination of genomic and environmental factors. Engaging in regular physical exercise prevents many chronic diseases, […]