By Reuters Staff April 15, 2019 NEW YORK (Reuters Health) – Metformin is associated with worse cognitive function in older adults, which could be explained by B-vitamin deficiency, new research suggests. “Fortified foods can provide a bioavailable source of B-vitamins and may be beneficial for maintaining better cognitive health in older people with or at […]
March 16, 2016 The Journal of Clinical Endocrinology and Metabolism TAKE-HOME MESSAGE The risk of vitamin B12 deficiency in diabetic patients treated with metformin was evaluated in the secondary analysis of the Diabetes Prevention Program (DPP)/Diabetes Prevention Program Outcomes Study (DPPOS). Both short-term and long-term metformin use were associated with combined low and borderline-low B12 […]
In Some Patients Metformin Impairs Thinking-Vitamin B12 may Help Published: Sep 9, 2013 | Updated: Sep 9, 2013 By Kristina Fiore, Staff Writer, MedPage Today The widely acclaimed diabetes drug metformin was linked with impaired brain function in patients who took the drug, although supplementation with vitamin B12 may alleviate metformin-induced deficiencies, according to new […]
David S.H. Bell, MD Disclosures South Med J. 2010;103(3):265-267. ABSTRACT AND INTRODUCTION Abstract Chronic metformin use results in vitamin B12 deficiency in 30% of patients. Exhaustion of vitamin B12 stores usually occurs after twelve to fifteen years of absolute vitamin B12 deficiency. Metformin has been available in the United States for approximately fifteen years. Vitamin B12 […]