Weight Loss

Weight loss is associated with reduced risk of knee and hip replacement: a survival analysis using Osteoarthritis Initiative data

Zubeyir Salis, Amanda Sainsbury, Helen I. Keen, Blanca Gallego & Xingzhong Jin International Journal of Obesity (2022) Abstract Objective To describe the association between body weight change and the risk of knee replacement and hip replacement. Design Time-to-event survival analysis from a population-based cohort of participants who had or were at risk of clinically significant […]

Weight Loss Program for GERD Relief?

— In patients with BMI over 25, nearly 50% reduced use of acid blockers or stopped altogether by Zaina Hamza, Staff Writer, MedPage Today October 26, 2021 Gastroesophageal reflux disease (GERD) patients who were overweight were able to limit the need for acid-blocking medications and shed pounds when they enrolled in a multidisciplinary weight management […]

Let’s Focus More on What We Eat, Not How Much

— The carbohydrate-insulin model of obesity offers a new way to conceptualize energy balance by David S. Ludwig, MD, PhD October 18, 2021 The First Law of Thermodynamics, formulated in the 1800s, says that energy can neither be created nor destroyed. For the human body, this principle of physics means that if you consume more […]

Vegan Diet Brings Slew of Metabolic Benefits in Randomized Trial

— Tops among them: weight loss by Kristen Monaco, Staff Writer, MedPage Today November 30, 2020 A plant-based diet low in fat yielded several metabolic benefits, according to a new trial. Over a 16-week period, adults with overweight or obesity who were randomized to a low-fat vegan diet lost an average 13 pounds (95% CI […]

Different Weight Loss Surgeries Tied to Different Micronutrients

— Study compared restrictive versus malabsorptive procedures by Kristen Monaco, Staff Writer, MedPage Today June 9, 2020 Differences in the type of bariatric surgery (or in the patients receiving it) meant different outcomes in metabolic profiles down the line, according to a study from Singapore. In a comparison of Roux-en-Y gastric bypass and one-anastomosis gastric […]

Very-low-calorie ketogenic diets with whey, vegetable or animal protein in patients with obesity: A randomized pilot study

Basciani S, Camajani E, Contini S, et al Journal of Clinical Endocrinology and Metabolism|June 3, 2020 In this randomized pilot study, researchers contrasted the effectiveness, safety and impact of 45-day isocaloric very-low-calorie ketogenic diets (VLCKDs) incorporating whey, vegetable or animal protein on the microbiota in patients with obesity and insulin resistance to test the assumption […]

Effectiveness of Weight-Loss Interventions for Reducing Pain and Disability in People With Common Musculoskeletal Disorders: A Systematic Review With Meta-Analysis

Abstract Objective To assess the effectiveness of weight-loss interventions on pain and disability in people with knee and hip osteoarthritis (OA) and spinal pain. Design Intervention systematic review. Literature Search Twelve online databases and clinical trial registries. Study Selection Criteria Randomized controlled trials of any weight-loss intervention (eg, diet, physical activity, surgical, pharmaceutical) that reported […]

Effectiveness of Weight Loss Interventions for Reducing Pain and Disability in People With Common Musculoskeletal Disorders: A Systematic Review With Meta-Analysis

Journal of Orthopaedic & Sports Physical Therapy Published Online:April 9, 2020 Volume0 Issue0 Pages1-55 https://www.jospt.org/doi/10.2519/jospt.2020.9041 Abstract Objective To assess the effectiveness of weight loss interventions on pain and disability in people with knee and hip osteoarthritis (OA) and spinal pain. Design Intervention systematic review. Literature Search Eight online databases and clinical trial registries. Study Selection […]

Study: Big Breakfast Better for Weight Loss

— Diet-induced thermogenesis “revved-up” in the morning by Jeff Minerd, Contributing Writer, MedPage Today February 20, 2020 The body uses more than twice as much energy to digest breakfast than dinner, a finding that emphasizes the importance of breakfast for weight loss, scientists said. In 16 volunteers who spent 3 days in a lab under […]

The Fat Hormone: How Effective are You at Burning Belly Fat?

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S.,CFMP Leptin, a recently discovered hormone, regulates body weight by suppressing food intake and/or increasing energy expenditure. Leptin is a very powerful and influential hormone produced by fat cells. Science has discovered that leptin is the most powerful metabolic regulator that tells your brain whether you should be hungry, eat and make […]

When should unexpected weight loss warrant further investigation to exclude cancer?

BMJ 2019; 366 doi: https://doi.org/10.1136/bmj.l5271 (Published 23 September 2019) Cite this as: BMJ 2019;366:l5271 What you need to know Unexpected weight loss can be associated with cancer, but also with a range of other conditions Weight loss codes in primary care typically represent ≥5% loss within a 6 month period, but there is a lack […]

The Ketogenic Diet for Obesity and Diabetes—Enthusiasm Outpaces Evidence

Viewpoint July 15, 2019 Shivam Joshi, M JAMA Intern Med. Published online July 15, 2019. doi:10.1001/jamainternmed.2019.2633 The ketogenic diet has recently received much attention for its promise of treating obesity and type 2 diabetes. However, the enthusiasm for its potential benefits exceeds the current evidence supporting its use for these conditions. Although the temptation is great […]

Does Skipping Breakfast Lead to Weight Loss or Weight Gain?

May 1, 2019 Rita Rubin, MA JAMA. Published online May 1, 2019. doi:10.1001/jama.2019.2927 Back in 1917, the same year that she cofounded the American Dietetic Association (now the Academy of Nutrition and Dietetics), Lenna Frances Cooper authored an article in Good Health magazine that noted “in many ways the breakfast is the most important meal of the day, because […]

Study reveals best exercises for reducing body fat

Naveed Saleh, MD, MS, for MDLinx | April 18, 2019 Both interval training and moderate-intensity continuous training (MOD) reduce body fat percentage, according to a recent review published in the British Journal of Sports Medicine. Interval training, however, offers a 28.5% greater reduction in total absolute fat mass. “Interval training may elicit greater weight loss […]

Weight loss regimen in obese and overweight individuals is associated with reduced cartilage degeneration: 96-month data from the osteoarthritis initiative

Osteoarthritis and Cartilage — Gersing AS, et al. | March 01, 2019 In this investigation, researchers studied changes in the composition of knee cartilage in overweight and obese participants with constant weight vs those with weight loss over 96 months, and evaluated how different weight loss regimens are associated with these changes. The study sample […]

How Weight Loss ‘Wakes Up the Beta Cell’ in T2D

Roy Taylor, MD, talks mechanisms and why that means urgency in the clinic by Crystal Phend, Senior Associate Editor, MedPage Today July 22, 2018 Remission of type 2 diabetes achieved by a large proportion of patients with a weight-loss intervention in the DiRECT trial emphasized the importance of excess body fat in the disease. Now researchers have been uncovering just […]

16:8 fasting diet actually works, study finds

June 20, 2018 By Ana Sandoiu A form of intermittent fasting known as the 16:8 diet helps obese individuals to lose weight and lower their blood pressure, according to a new study. More and more people now turn to intermittent fasting as a fast and effective way to lose weight. There are different form of this diet, depending […]

For Knee Osteoarthritis, More Weight Loss Is Better

Clinical and mechanistic improvements seen with weight loss of 20% or more by Nancy Walsh, Senior Staff Writer, MedPage Today June 20, 2018 Older adults with knee osteoarthritis (OA) who lost 20% or more of their body weight had significant improvements in pain and function, and experienced benefits on multiple other clinical and mechanistic outcomes, a secondary analysis […]

Nonstick Chemicals May Disrupt Metabolic Function in Women

~ Higher PFAS concentrations tied to weight regain, slower metabolism by Kristen Monaco, Staff Writer, MedPage Today February 13, 2018 Long-term weight maintenance may be compromised by exposure to compounds used in many consumer products to make them nonstick or waterproof and that are thought to be endocrine-disrupting chemicals, researchers reported. In a subanalysis of […]

After a Year, Low-Carb Diet Helps Many Patients Reverse Type 2 Diabetes, Lose Weight, and Stop Insulin

February 12, 2018 Mary Caffrey Of the 262 patients with type 2 diabetes in the intervention, 83% stuck with it through the first year, despite significant requirements. Patients with type 2 diabetes (T2D) who spent a year limiting carbohydrates—while their biomarkers were closely watched to keep them in a metabolic state to burn fat—showed sharp […]