Gastrointestinal System

Low FODMAP diet improves leaky gut in study

July 30, 2025 The GIST Low FODMAP diet improves leaky gut in study by University of Michigan Edited by Gaby Clark, reviewed by Andrew Zinin In a study, patients with irritable bowel syndrome with diarrhea, or IBS-D, who went on a low FODMAP diet saw an improvement of colonic barrier dysfunction, commonly known as “leaky […]

The Real-World Impact of Vitamin D Supplementation on Inflammatory Bowel Disease Clinical Outcomes

July 22, 2025 Clinical Gastroenterology and Hepatology Jared A. Sninsky Abstract Background & Aims Vitamin D deficiency is common in inflammatory bowel disease (IBD) and linked to adverse outcomes, yet the therapeutic role of vitamin D supplementation remains uncertain. We evaluated the real-world impact of vitamin D supplementation on corticosteroid use, emergency department visits, and […]

Effect of Phospholipid Curcumin Meriva® on Liver Histology and Kidney Disease Outcomes in Patients With NASH

July 10, 2024 Hepatology (Baltimore, Md.) TAKE-HOME MESSAGE This study assessed the safety and efficacy of treatment with phospholipid curcumin (Meriva®), a phospholipid formulation with ameliorated systemic curcumin absorption and delivery, in patients with NASH. A total of 52 patients with NASH (a majority of whom had fibrosis and chronic kidney disease) were randomized to […]

A Functional Medicine Approach to Fibromyalgia

Written by Amy Myers, MD It is estimated that fibromyalgia affects nearly 6 million or 1 in 50 people, causing chronic pain, particularly muscle pain, fatigue, sleep disturbances, brain fog, or cognitive impairment, depression, and painful tender points throughout the body. Not surprisingly, conventional medicine focuses only on managing symptoms through pain medications and antidepressants. […]

Dietary treatment found to be more effective than medicines in irritable bowel syndrome

Published April 22, 2024 | Originally published on MedicalXpress Breaking News-and-Events A study conducted at the University of Gothenburg found that with dietary adjustments, more than 7 out of 10 irritable bowel syndrome (IBS) patients had significantly reduced symptoms, compared with medications. The work is published in The Lancet Gastroenterology & Hepatology journal. IBS is […]

Gut Microbes May Play a Role in AS

— Genes associated with ankylosing spondylitis act at least in part through effects on the gut microbiome. by Diana Swift, Contributing Writer, MedPage Today December 4, 2014 Patients with ankylosing spondylitis (AS) had a more diverse intestinal microbiota and a greater abundance of intestinal microbes, some of which are linked to severe intestinal inflammation, according […]

Phase 3 trial finds amitriptyline helps relieve IBS symptoms

Published October 17, 2023 | Originally published on MedicalXpress Breaking News-and-Events A cheap and widely available prescription drug can improve symptoms of irritable bowel syndrome in patients seen in GP surgeries, new research presented today at UEG Week 2023 has found. Amitriptyline, which is commonly used at low doses for a range of health concerns, […]

Curcumin and Proton Pump Inhibitors for Functional Dyspepsia

October 02, 2023 BMJ Evidence-Based Medicine

Drinking one soda or sweetened beverage per day may increase the risk of liver disease and cancers, according to new study

By Lisa Marie Basile | Fact-checked by Davi Sherman | Published September 20, 2023 Key Takeaways Findings from a new study published in JAMA explored the effects of sugary beverage intake in 98,786 postmenopausal women over an average follow-up of 20.9 years. They found that women who drank one or more servings daily of sweetened beverages—compared with […]

Ginger and peppermint: Two herbal heavy-hitters to treat nausea, naturally

By Jules Murtha | Fact-checked by Anastasia Climan, RDN, CD-N | Published May 30, 2023 Key Takeaways The rhizome of the plant Zingiber officinale, also known as ginger, has been used for thousands of years to treat stomach upset and aid digestion. Studies show that peppermint (Mentha piperita) may be used in complementary medicine to reduce […]

Study shows melatonin, commonly used to improve sleep, can aggravate bowel inflammation

Published May 10, 2023 An article published in the journal Microorganisms shows that melatonin, despite its antioxidant effects and role in regulating sleep cycles, can worsen inflammation of the intestine and impair the action of gut microbiota. This community of bacteria and other microbes is important to health, helping control digestion and benefiting the immune system. An […]

Overprescribed Antibiotics for Colds Causes Patient Harm

April 30, 2023 Researchers identify hundreds of thousands of cases of resulting diarrhea, candidiasis, and Clostridium difficile infections needing medical attention THURSDAY, April 27, 2023 (HealthDay News) — Overprescribing of antibiotics for acute upper respiratory infections (aURIs) causes significant patient harm, according to a study published in the April issue of the Journal of Internal […]

Plant Compound Shows Promise for Alleviating Food Allergies

Study uncovers new drug targets for treating other allergic disorders 25-Mar-2022 9:00 AM EDT, by Federation of American Societies for Experimental Biology (FASEB) Newswise — Philadelphia (April 1, 2022) — Researchers combined advanced computational methods with experimental studies to gain new insight, at the cell level, into how the plant compound formononetin might be used to treat food […]

Scientists discover link between gut microbiota and chronic inflammatory diseases like arthritis

MedicalXpress Breaking News-and-Events | January 25, 2022 An international research team has established a link between gut microbiota and chronic inflammatory diseases such as arthritis. The team led by Éric Boilard of Université Laval has discovered that a protein naturally present in the gut acts on the microbiota and causes the formation of molecules that […]

Acupuncture for Opioid-Induced Constipation

Acupuncture Today – December, 2021, Vol. 22, Issue 12 BY EDITORIAL STAFF Opioid prescribing remains an all-too-common reality in the United States and elsewhere despite increasing national and international guidelines emphasizing their dangers and promoting drug-free pain-relief, including acupuncture, as a first option. But for patients taking opioids, acupuncture also can help, relieving one of […]

The Straight Poop on Who Benefited From a Squatting Stool

— Assist device was helpful for a particular subgroup of patients by Zaina Hamza, Staff Writer, MedPage Today October 27, 2021 For women with defecatory dysfunction, those with normal stool consistency, greater rectoanal pressure gradient, lower anal tone, and of younger age (<50 y/o) were most likely to benefit from a squatting assist stool (SAS), […]

Weight Loss Program for GERD Relief?

— In patients with BMI over 25, nearly 50% reduced use of acid blockers or stopped altogether by Zaina Hamza, Staff Writer, MedPage Today October 26, 2021 Gastroesophageal reflux disease (GERD) patients who were overweight were able to limit the need for acid-blocking medications and shed pounds when they enrolled in a multidisciplinary weight management […]

Defective epithelial barriers linked to 2 billion chronic diseases

MAY 6, 2021 by University of Zurich Humans are exposed to a variety of toxins and chemicals every day. According to the epithelial barrier hypothesis, exposure to many of these substances damages the epithelium, the thin layer of cells that covers the surface of our skin, lungs and intestine. Defective epithelial barriers have been linked […]

Low Oxalates Foods May Help Reduce Auto-Immune Disease Risk, Autism and Fibromyalgia

Ronald Grisanti D.C., D.A.B.C.O., DACBN, MS, CFMP Oxalate (or oxalic acid) is a compound found in a variety of plant-based foods. Under a microscope, oxalates are jagged in structure and look somewhat crystalline. During metabolism, oxalic acid combines with other minerals like calcium, sodium, magnesium, and potassium to form compounds like calcium oxalate and sodium oxalate […]

Efficacy and Safety of OTC Therapies for Chronic Constipation

April 26, 2021 The American Journal of Gastroenterology TAKE-HOME MESSAGE This is an updated review on over-the-counter laxatives for constipation. Senna and polyethylene glycol have the highest level of evidence. Fiber, stimulant laxatives, and magnesium salts have moderate levels of evidence for efficacy. No serious adverse events were noted with these therapies. –  Mukund Venu, MD, FACG INTRODUCTION […]