Microbiome

Gut Microbes May Play a Role in AS

— Genes associated with ankylosing spondylitis act at least in part through effects on the gut microbiome. by Diana Swift, Contributing Writer, MedPage Today December 4, 2014 Patients with ankylosing spondylitis (AS) had a more diverse intestinal microbiota and a greater abundance of intestinal microbes, some of which are linked to severe intestinal inflammation, according […]

Scientists discover link between gut microbiota and chronic inflammatory diseases like arthritis

MedicalXpress Breaking News-and-Events | January 25, 2022 An international research team has established a link between gut microbiota and chronic inflammatory diseases such as arthritis. The team led by Éric Boilard of Université Laval has discovered that a protein naturally present in the gut acts on the microbiota and causes the formation of molecules that […]

A Novel Gut Bacteria Noted to Help Combat Obesity, Diabetes and Heart Disease

by Ronald Grisanti D.C., D.A.B.C.O., DACBN, MS, CFMP As science continues to emerge in gut research, novel gut bacteria are discovered. Akkermansia muciniphila has emerged as the “sentinel of the gut” and has been shown to promote gut barrier integrity, modulate immune response and inhibit inflammation. Adequate levels of Akkermansia muciniphila provides that extra mucus layer […]

Study finds high-fiber diet brings significant changes to human gut microbiome

MARCH 26, 2021 by University of California, Irvine A short-term intervention in daily fiber consumption can significantly alter the gut microbiome and nutrient intake, according to a study led by University of California, Irvine researchers. The research was recently published by the American Society for Microbiology. Dietary fiber consists of resistant carbohydrates found in fruits, […]

Gut microbes: the key to normal sleep

MedicalXpress Breaking News-and-Events|November 30, 2020 With fall and winter holidays coming up, many will be pondering the relationship between food and sleep. Researchers led by Professor Masashi Yanagisawa at the University of Tsukuba in Japan hope they can focus people on the important middlemen in the equation: bacterial microbes in the gut. Their detailed study […]

Human intervertebral discs harbour a unique microbiome and dysbiosis determines health and disease

Published: 14 May 2020 Shanmuganathan Rajasekaran European Spine Journal (2020) Abstract Background To document the role of sub-clinical infections in disc disorders and investigate the existence of microbiome in intervertebral discs (IVD). Methods Genomic DNA from 24 lumbar IVDs [8—MRI normal discs (ND) from brain dead yet alive organ donors, 8—disc herniation (DH), 8—disc degeneration […]

‘First Evidence’ Links Gut Bacteria, Fibromyalgia

Deborah Brauser July 09, 2019 Patients with fibromyalgia appear to have specific gut microbiome alterations that differ from their healthy peers, new research suggests. In the “first evidence” to show this connection, investigators found that women with fibromyalgia had significant differences in 19 species of gut bacteria compared with healthy controls. They also had higher […]

Type 1 diabetes linked to gut inflammation, bacteria changes

Date: January 19, 2017 Source: Endocrine Society Summary: People with Type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria, a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a new study. People with Type 1 diabetes exhibit inflammation in the digestive tract […]

Migraine Linked to Mouth Bacteria

Pauline Anderson October 21, 2016 Researchers may have uncovered a mechanism behind nitrate-based triggers in migraine. They found that compared with people who don’t experience migraines, those who do have significantly more nitrate, nitrite, and nitric oxide reductase genes in oral and fecal samples. For this study, the investigators examined these genes in stool and […]

Asthma – An Epidemic Explained

DAVIDPERLMUTTER So much has been written in scientific journals recently about how the loss of microbes in the gut, especially earlier in life, affects the immune system. For example, researcher Marsha Wills-Karp, at the Johns Hopkins School of Public Health, recently revealed how early life exposure to antibiotics is associated with a substantial increased risk […]

Gut microbes linked to major autoimmune eye disease

Date: August 18, 2015 Source: Cell Press Summary: One major cause of human blindness is autoimmune uveitis, which is triggered by the activation of T cells, but exactly how and where the T cells become activated in the first place has been a long-standing mystery. A study reveals that gut microbes produce a molecule that […]

Effects of high doses of vitamin D3 on mucosa-associated gut microbiome vary between regions of the human gastrointestinal tract

Eur J Nutr. 2015 Jul 1. [Epub ahead of print] Bashir M1, Prietl B, Tauschmann M, Mautner SI, Kump PK, Treiber G, Wurm P, Gorkiewicz G, Högenauer C, Pieber TR. Abstract PURPOSE: Vitamin D is well known for its effects on bone mineralisation but has also been attributed immunomodulatory properties. It positively influences human health, […]

The Autism Enigma – Video

https://youtu.be/bJHetXfqaHU YouTube Link

Connecting the Microbiome and Antibiotics to Obesity – Video

Eric J. Topol, MD, Martin J. Blaser, MD Disclosures April 13, 2015 See Video Interview Tracing a Path From Campylobacter to the Microbiome Eric J. Topol, MD: Hello. I’m Eric Topol, editor-in-chief of Medscape, and I am pleased to have Dr Martin Blaser join me for this One-on-One interview. Dr Blaser runs the Human Microbiome Center at New […]

Antibiotics Raise Diabetes Risk via Gut Microbiota

Do Antibiotics Raise Diabetes Risk via Gut Microbiota? Liam Davenport April 01, 2015 People who take multiple courses of antibiotics may face an increased risk of developing both type 1 and type 2 diabetes, potentially through alterations in gut microbiota, conclude US researchers. The team, led by Ben Boursi, MD, a postdoctoral researcher in the department of […]

HOW TO HEAL A LEAKY GUT

CATHERINE GUTHRIE · MARCH 2015 Your intestines are home to a great deal of your digestive system, nervous system, and immune system. Here’s how to keep them healthy. Modern life is hard on your gut. Your entire digestive tract can be affected by stress, processed foods, alcohol, medications, and bacteria. All that chronic irritation can lead to inflammation and, […]

The gut virome in inflammatory bowel disease patients differed from those without the disease

Beyond bacteria: The gut virome in inflammatory bowel disease patients differed from those without the disease, researchers reported in Cell. Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease Jason M. Norman Highlights • The enteric virome is abnormal in multiple inflammatory bowel disease patient cohorts • The enteric virome richness increases in Crohn’s […]

Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena? – Full Text

Am J Gastroenterol advance online publication 27 January 2015; doi: 10.1038/ajg.2014.427 Mirjana Rajilić-Stojanović PhD Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena? Abstract Irritable bowel syndrome (IBS) is a heterogeneous functional disorder with a multifactorial etiology that involves the interplay of both host and environmental factors. Among environmental factors relevant for IBS etiology, […]

How NOT to have diabetes

By Dr. Davis | January 8, 2015 If you want type 2 diabetes , follow conventional advice to cut fat and eat more “healthy whole grains.” (This is also true for type 1 diabetes in susceptible individuals with pancreatic beta cell autoimmunity triggered by wheat gliadin or corn zein.) But what if you don’t want to […]

Pediatric Arthritis, Look to the Gut

— The intestinal microbiota may act as a trigger in pediatric enthesitis-related arthritis. by Nancy Walsh, Senior Staff Writer, MedPage Today December 3, 2014 Alterations in the intestinal microbiota have been identified in children with enthesitis-related arthritis (ERA), suggesting the possibility that the microbiome may play a triggering role in the disease, researchers reported. Among […]