Diabetes Type I

Studies show vitamin D fights these 3 diseases

Alistair Gardiner|November 25, 2020 How often do you get out and enjoy the sunshine? If the answer is not much, you may want to start thinking about other ways to get a regular dose of vitamin D. According to estimates, vitamin D deficiency affects roughly 1 billion people worldwide—and almost half the global population has at […]

A Daily Dose of This Can Help Fight Chronic Conditions

by Naveed Saleh,MD May 19, 2020 When we think about sunlight and health, we usually associate exposure to the sun with negative consequences like sunburn and skin cancer. And it’s true—ultraviolet A and B radiation exposure can cause sunburn, damage to collagen fibers, vitamin A destruction in the skin, accelerated skin aging, as well as […]

Diabetes in Osteoarthritis: Pain Is Worse

— Association was independent of obesity and radiographic severity by Nancy Walsh, Senior Staff Writer, MedPage Today March 3, 2020 Among patients with knee osteoarthritis (OA), pain was greater for those with coexisting diabetes mellitus (DM), and this association was independent of obesity and radiographic severity, European researchers found. In an analysis that adjusted for […]

Leaky Gut, Leaky Brain: The Role of Zonulin

by Melissa Lee – Fx Medicine 05/13/2016 DOWNLOAD INFOGRAPHIC In recent years an amazing discovery has advanced our understanding of intestinal permeability. In 2000, Dr Alessio Fasano and his team discovered a molecule responsible for modulating intestinal tight junctions (TJs) known as zonulin. To date, zonulin is the only human protein known to reversibly regulate intestinal permeability. Based on Dr Fasano’s […]

Carb-Light Diet Helps T1D Patients Achieve Glycemic Control

‘Very low-carbohydrate diet’ of less than 50 g per day by Kristen Monaco, Staff Writer, MedPage Today May 07, 2018 Among people with type 1 diabetes, following a very low-carbohydrate diet (VLCD) can aid in achieving glycemic control, researchers suggested. Responses from an online survey of people with type 1 diabetes found that those who […]

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8. Thaiss CA. Abstract Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse models of obesity and diabetes that hyperglycemia drives intestinal barrier permeability, through GLUT2-dependent transcriptional reprogramming of intestinal […]

Very High Prevalence of Frozen Shoulder in Patients With Type 1 Diabetes of ≥45 Years’ Duration: The Dialong Shoulder Study

Niels Gunnar Juel, MD Archives of Physical Medicine and Rehabilitation August 2017 Volume 98, Issue 8, Pages 1551–1559 Highlights Of patients with type 1 diabetes for ≥45 years, 59% had frozen shoulder, with 73% affected bilaterally. Patients with painful frozen shoulder had highest disability and least shoulder mobility. High glycemic index was associated with severe disability […]

Type 1 diabetes linked to gut inflammation, bacteria changes

Date: January 19, 2017 Source: Endocrine Society Summary: People with Type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria, a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a new study. People with Type 1 diabetes exhibit inflammation in the digestive tract […]

Celiac Disease and Risk of Autoimmune Disorders

April 12, 2016 The Journal of Pediatrics TAKE-HOME MESSAGE Children with celiac disease (CD) were matched with healthy controls to evaluate the relative risk of type 1 diabetes mellitus (T1DM) and autoimmune thyroid disease. Children with CD were at significantly increased risk of developing hypothyroidism compared with controls (HR 4.64). There was also an increased […]

Microbiome linked to type 1 diabetes: Shift in microbiome species diversity prior to disease onset

Date: February 5, 2015 Source: Broad Institute of MIT and Harvard Summary: In one of the largest longitudinal studies of the microbiome to date, researchers have identified a connection between changes in gut microbiota and the onset of type 1 diabetes. The study, which followed infants who were genetically predisposed to the condition, found that […]

Glycemic Control and Excess Mortality in Type 1 Diabetes

November 25, 2014 The New England Journal of Medicine TAKE-HOME MESSAGE The authors of this registry-based observational study of a Swedish population of patients with type 1 diabetes (N = 33,915) determined the excess risk for death according to level of glycemic control. After a mean follow-up of 8 years, 8% of patients with diabetes […]