November 07, 2021 BMJ : British Medical Journal TAKE-HOME MESSAGE This comprehensive systematic review and network meta-analysis assesses the efficacy and safety of multiple preparations and doses of NSAIDs, opioids, and acetaminophen for clinically relevant reductions in pain caused by knee and hip osteoarthritis. The review includes nearly 200 randomized controlled trials comprised of over 100,000 […]
Don’t expect relief to last beyond a few months by Nancy Walsh, Senior Staff Writer, MedPage Today March 29, 2019 Pain relief from nonsteroidal anti-inflammatory drugs (NSAIDs) in knee osteoarthritis (OA) was rapid but declined over time, a large meta-analysis demonstrated. Data from 72 randomized controlled trials found that statistically significant reductions in pain peaked […]
Reuters Health News | September 24, 2018 The commonly used painkiller diclofenac may be linked with an increased risk of heart problems, a large Danish study suggests. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that’s often used to treat arthritis and other painful joint conditions. In many countries, it’s available without a prescription. Researchers found […]