Atherosclerosis

Genes Confirm LDL Causes Aortic Stenosis

Published: Oct 27, 2014 By Crystal Phend, Senior Staff Writer, MedPage Today Story Source High LDL cholesterol appears to cause aortic stenosis, even though lipid-lowering trials in established valve disease haven’t worked, a genetic study suggested. In the Mendelian randomization study — using genetic allocation conferred at conception akin to trial randomization — weighted genetic […]

Intestinal Flora May Promote Atherosclerosis

Published: Apr 24, 2013 | Updated: Apr 25, 2013 By Crystal Phend , Senior Staff Writer, MedPage Today Story Source Action Points The gut microbiota appears to play a role in atherosclerosis through a complex metabolic pathway that involves dietary lecithin. Point out that levels of atherosclerosis-related trimethylamine-N-oxide (TMAO) released by the process were dependent […]

Stop Hardening of the Arteries with this Fruit

YourMedicalDectective.com Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. What if there was a fruit that protected you from hardening of the arteries and even if eating a high fat diet was shown to reduce plaque build-up in your arteries. Well there is such a fruit and it is the simple grapefruit! Grapefruit contains a powerful food […]

Effects of alcohol and polyphenols from beer on atherosclerotic biomarkers in high cardiovascular risk men

Effects of alcohol and polyphenols from beer on atherosclerotic biomarkers in high cardiovascular risk men: A randomized feeding trial Nutrition, Metabolism & Cardiovascular Diseases, 08/05/2014 Clinical Article Chiva-Blanch G, et al. – The authors aimed to evaluate the effects of ethanol and the phenolic compounds of beer on classical and novel cardiovascular risk factors. The […]

Stop Hardening of the Arteries with this Fruit

Stop Hardening of the Arteries with this Fruit Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. What if there was a fruit that protected you from hardening of the arteries and even if eating a high fat diet was shown to reduce plaque build-up in your arteries. Well there is such a fruit and it is the […]

Egg consumption and insulin metabolism in the Insulin Resistance Atherosclerosis Study (IRAS)

Lee CT Public Health Nutr. 2014 Jul;17(7):1595-602. doi: 10.1017/S1368980013001572. Epub 2013 Jun 19. PubMed Reference Journal Reference Abstract OBJECTIVE: To examine the association between egg consumption and measures of insulin sensitivity (SI), acute insulin response (AIR) and metabolic clearance rate of insulin (MCRI). DESIGN: Cross-sectional analysis. Settings Egg consumption, categorized as <1/week, 1 to <3/week, […]

Extra virgin olive oil blunt post-prandial oxidative stress via NOX2 down-regulation

Atherosclerosis, 06/30/2014 Clinical Article PubMed Reference Journal Reference Carnevale R, et al. – The authors speculated that olive oil could inhibit oxidative stress, which is believed to be implicated in the atherosclerotic process. The study provides the first evidence that post–prandial oxidative stress may be triggered by NOX2 up–regulation. EVOO but not corn oil, is […]

Bacteria Present in Carotid Arterial Plaques Are Found as Biofilm Deposits Which May Contribute to Enhanced Risk of Plaque Rupture

Bernard B. Lanter, Karin Sauer, David G. Davies Department of Biological Sciences, Binghamton University, Binghamton, New York, USA doi: 10.1128/mBio.01206-14 10 June 2014 mBio vol. 5 no. 3 e01206-14 Full Text Article ABSTRACT Atherosclerosis, a disease condition resulting from the buildup of fatty plaque deposits within arterial walls, is the major underlying cause of ischemia […]

Stop Hardening of the Arteries with this Fruit

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. Story Source What if there was a fruit that protected you from hardening of the arteries and even if eating a high fat diet was shown to reduce plaque build-up in your arteries. Well there is such a fruit and it is the simple grapefruit! Grapefruit contains a powerful […]

“Eskimo Diet” — or “Inuit Diet,” which is heavy on whale and seal blubber — appears to have a shaky foundation

Investigators find something fishy with classical evidence for dietary fish recommendation Oily fish are currently recommended as part of a heart healthy diet. This guideline is partially based on the landmark 1970s study from Bang and Dyerberg that connected the low incidence of coronary artery disease (CAD) among the Eskimos of Greenland to their diet, […]

Fatty Liver Tied to Diabetes, Atherosclerosis

Published: Apr 11, 2014 By Michael Smith, North American Correspondent Full Story  Action Points Note that these studies were published as abstracts and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. LONDON — Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of […]

Dietary macronutrients, genetic variation, and progression of coronary atherosclerosis among women

American Heart Journal, 03/28/2014 Clinical Article Kalantarian S, et al. – Previous studies observed the surprising finding that saturated fat was inversely associated with atherosclerosis progression in postmenopausal women, whereas polyunsaturated fat (PUFA) and carbohydrates were positively associated. Whether certain genes modify the association of diet with atherosclerotic progression is unknown. The authors observed an […]

Diet and the Intestinal Microbiome: Implications for Health

Gastroenterology 2014 Feb 03;[EPub Ahead of Print], LG Albenberg, GD Wu Review · February 24, 2014 Full Story Journal Reference TAKE-HOME MESSAGE The influence of diet on the structure and metabolism of the intestinal microbiota is reviewed. Differences in diet, even short-term changes, can result in significant changes in the microbiota, and metabolic products from the […]

Beyond Cholesterol

JANUARY 20, 2014 BY CHRISTOPHER MASTERJOHN Article Summary • Between 1928 and 1945, Weston Price measured the fat-soluble vitamin content of over twenty thousand samples of butterfat from many different regions. He found that abundant sunshine and rainfall, together with high-quality soil, was associated with high concentrations of vitamins within the butter and fewer deaths […]

Mummies and the Tale of the Clogged Arteries, an Update

01.03.2014 Looking for atherosclerosis in mummies brings the thrill of scientific discovery, but getting access to the ‘patients’ can prove difficult. by Todd Neale Senior Staff Writer, MedPage Today Looking for atherosclerosis in mummies brings the thrill of scientific discovery, but getting access to the “patients” can prove difficult. In the Horus study, an international […]

PREDIMED MRI Substudy: Regression of Plaque Volume With Mediterranean Diet

Michael O’Riordan June 03, 2014 MADRID, SPAIN — An analysis of the primary-prevention PREDIMED study provides  further evidence as to why a Mediterranean diet is able to reduce the risk of cardiovascular disease[1]. In a substudy of the trial, investigators report that individuals who adhered to the Mediterranean diet supplemented with extra virgin oil had significant regression […]

Coronary artery calcium (CAC) scores and dyslipidemia in relation to outcomes of cardiovascular disease

The CAC score was better correlated with cardiac events than cholesterol levels.

Gum Health Associated With Carotids?

Published: Nov 5, 2013 | Updated: Nov 6, 2013 By Todd Neale, Senior Staff Writer, MedPage Today Full Story:  http://www.medpagetoday.com/Cardiology/Atherosclerosis/42727 Action Points Previous studies have indicated that the burden of periodontal disease-causing bacteria was cross-sectionally related to increased carotid intima-media thickness. In this study, longitudinal improvement in clinical and microbial periodontal status was related to […]

Calcium Score Beats Lipids for Telling CVD Risk

Published: Oct 22, 2013 | Updated: Oct 22, 2013 By Cole Petrochko, Staff Writer, MedPage Today Full Story:  http://www.medpagetoday.com/Cardiology/Atherosclerosis/42415 Action Points In this study of patients who were not on baseline medications for dyslipidemia, coronary artery calcium appeared to classify atherosclerotic cardiovascular risk better than counting lipid abnormalities. Across the spectrum of dyslipidemia, event rates […]

Early Life Holds Clues to Adult Heart Health

Published: Sep 30, 2013 | Updated: Oct 1, 2013 By Todd Neale Full Story:  http://www.medpagetoday.com/Cardiology/Prevention/41956 Action Points Note that this analysis of three cohort studies demonstrated that risk factors present in childhood are associated with cardiovascular disease in adulthood. Be aware that there was a substantial number of participants who were lost to follow-up; these […]