Cholesterol Issues

Association Between Hypercholesterolemia and Neck Pain in a Cross-sectional Population-based Study

Ahorukomeye, Peter BSa,b; Mahajan, Arushi BSb; Du, Jerry Y. MDa; Yu, Charles C. MDc; Bhandutia, Amit K. MDd; Ahn, Nicholas U. MDa,b Spine 48(2):p 137-142, January 15, 2023. | DOI: 10.1097/BRS.0000000000004485 Abstract Study Design. Retrospective cross-sectional analysis. Summary of Background Data. Degenerative changes are a major contributor to chronic neck pain. According to the vascular […]

Pecans Appeared to Help Control Lipids in At-Risk Patients

— Fasting and post-meal cholesterol showed improvement, study found by Ed Susman, Contributing Writer, MedPage Today November 10, 2021 Sedentary individuals at risk for cardiovascular disease appeared to benefit from adding pecans to their regular diet, reducing bad cholesterol and triglycerides when compared with study participants who did not have pecans during an 8-week period, […]

Studies Relegate LDL to Lesser Role in Atherosclerotic Disease

— Is VLDL cholesterol a better prognosticator? by Nicole Lou, Staff Writer, MedPage Today December 1, 2020 LDL cholesterol turned out not to be the main lipid contributor to atherosclerotic cardiovascular disease (ASCVD) in two studies. Serum remnant cholesterol — the cholesterol carried on very low-density lipoproteins (VLDLs) and/or intermediate-density lipoproteins (IDLs), approximated by subtracting […]

Ditch the statins: 7 natural ways to lower your cholesterol levels

May 13, 2020 Naveed Saleh, MD, MS, for MDLinx Although statins are remarkably effective at lowering lipid levels, they have been mired in controversy, an imbroglio commonly referred to as the “statin wars.” Much of this controversy centers on the benefits of statins as primary prevention vs their adverse effects, most disconcertingly acute renal failure […]

Soy protein lowers cholesterol, study suggests

MedicalXpress Breaking News-and-Events | May 07, 2019 Soy protein has the ability to lower cholesterol by a small but significant amount, suggests a new study led by St. Michael’s Hospital in Toronto. With the US Food and Drug Administration (FDA) planning to remove soy from its list of heart healthy foods, researchers at St. Michael’s […]

Cholesterol and Dietary Supplements

Your body needs cholesterol to make hormones and other substances, but having too much of it in your blood is linked to higher risks of heart disease and stroke. High cholesterol has no symptoms; the only way to find out whether your cholesterol level is high is by having a blood test. A variety of […]

Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality – Full Text

March 19, 2019 Victor W. Zhong, PhD JAMA. 2019;321(11):1081-1095. doi:10.1001/jama.2019.1572 Key Points Question Is consuming dietary cholesterol or eggs associated with incident cardiovascular disease (CVD) and all-cause mortality? Findings Among 29 615 adults pooled from 6 prospective cohort studies in the United States with a median follow-up of 17.5 years, each additional 300 mg of dietary […]

Total cholesterol and all-cause mortality by sex and age: a prospective cohort study among 12.8 million adults – Full Text Article

Published: 07 February 2019 Sang-Wook Yi, Jee-Jeon Yi & Heechoul Ohrr Scientific Reports Volume 9, Article number: 1596 (2019) Abstract It is unclear whether associations between total cholesterol (TC) levels and all-cause mortality and the optimal TC ranges for lowest mortality vary by sex and age. 12,815,006 Korean adults underwent routine health examinations during 2001–2004, […]

Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease

January 29, 2019 Brian A. Ference, MD, MPhil, MSc JAMA. 2019;321(4):364-373. doi:10.1001/jama.2018.20045 Key Points Question  What is the clinical benefit of lowering plasma triglyceride levels compared with lowering low-density lipoprotein cholesterol levels? Findings  In mendelian randomization analyses involving 654 783 participants, triglyceride-lowering variants in the lipoprotein lipase gene and low-density lipoprotein cholesterol (LDL-C)–lowering variants in the LDL receptor gene […]

Why Does Anyone Eat Egg Whites?

THE EGGSONERATION CONTINUES: WHY DOES ANYONE EAT EGG WHITES? MAY 26, 2018 The skeptical cardiologist pointed out in 2013 that there was no good evidence supporting limiting dietary cholesterol to 300 mg per day.  I exulted, therefore, in 2016 , when this long-standing dietary recommendation came out of the US dietary guidelines. Recognizing that dietary cholesterol doesn’t need to […]

Curcumin potentiates cholesterol-lowering effects of phytosterols in hypercholesterolaemic individuals. A randomised controlled trial

Metabolism May 2018 Volume 82, Pages 22–35 Jessica J.A. Ferguson Abstract Background Dietary phytosterols (PS) are well-known hypocholesterolaemic agents. Curcumin elicits hypolipidaemic and anti-inflammatory effects in preclinical studies, however, consistent findings in humans are lacking. Objective Concurrent PS and curcumin supplementation may exhibit enhanced hypocholesterolaemic and anti-inflammatory effects to optimise cardio-protection. The objective of this […]

The Benefits of High Cholesterol

Uffe Ravnskov, MD, PhD People with high cholesterol live the longest. This statement seems so incredible that it takes a long time to clear one´s brainwashed mind to fully understand its importance. Yet the fact that people with high cholesterol live the longest emerges clearly from many scientific papers. Consider the finding of Dr. Harlan […]

Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors

Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: A meta-analysis of randomized controlled trials Nutrition Journal | October 13, 2017 Qin S, et al. – This study appraised turmeric and curcumin with respect to efficacy and safety in lowering blood lipids in patients at risk […]

Reducing inflammation without lowering cholesterol cuts risk of cardiovascular events

Inflammatory hypothesis confirmed: Landmark randomized clinical trial of high-risk patients finds that a drug targeting inflammation reduced risk of major adverse cardiovascular events Date: August 28, 2017 Source: Brigham and Women’s Hospital Summary: Investigators have announced results of a clinical trial culminating from 25 years of cardiovascular research work. The team reports a significant reduction […]

Red yeast rice preparations: are they suitable substitutions for statins?

The American Journal of Medicine Carlos A. Dujovne, MD Abstract Red yeast rice, a commercially available food supplement known to reduce serum cholesterol, has been repeatedly advocated as alternative therapy for hypercholesterolemic patients that refuse statins, cannot tolerate statin therapy’s side effects, or request a “naturopathic” medicine. Red yeast rice contains a fungus (Monascus purpureus), […]

Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review (Full Text)

Cardiovascular medicine Research Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review Uffe Ravnskov1, David M Diamond2, Rokura Hama3, Tomohito Hamazaki4, Björn Hammarskjöld5, Niamh Hynes6, Malcolm Kendrick7, Peter H Langsjoen8, Aseem Malhotra9, Luca Mascitelli10, Kilmer S McCully11, Yoichi Ogushi12, Harumi Okuyama13, Paul J Rosch14, Tore […]

Red Yeast Rice: A Regulatory Quagmire for Clinicians

Tuesday, 13 December 2016 15:50 By Erik Goldman If you’re recommending Red Yeast Rice supplements to patients as a natural alternative for cutting CVD risk, you may be unwittingly guiding them to ineffective products, and simultaneously compromising your clinical credibility. This is all thanks to a regulatory gray zone that permits supplement companies to market […]

3-4 Egg Yolks per Day May Normalize Your Lipids, Reduce Liver & Abdominal Fat as Well as Your CVD & NAFLD Risk

Because of their cholesterol content, eggs have long been touted as a driver of heart disease. As a SuppVersity reader, you know that there are multiple reasons why the notion that the consumption of eggs, or rather egg yolks, would increase your cardiovascular disease risk: (a) there’s no mechanistic “if your cholesterol is high, your CVD risk is […]

Garlic & Red Yeast Rice: Manage Your Blood Lipids W/Out Statins

“Twelve + 1”? I know that sounds odd, but I have my reason to single one of the natural alternatives, two scientists from the Chulalongkorn University in Thailand list in their 2016 review “A Review of the Efficacy, Safety, and Clinical Implications of Naturally Derived Dietary Supplements for Dyslipidemia”, right from the start: red yeast rice […]

No Association Between LDL Cholesterol and Mortality in the Elderly

6/24/2016 BMJ Open TAKE-HOME MESSAGE The authors investigated the association of LDL-C with mortality in the elderly by reviewing 19 cohort studies of individuals ≥60 years. In 16 of 28 cohorts, all-cause mortality was inversely associated with LDL-C, with no association in the remaining 12 cohorts. Cardiovascular mortality was also inversely associated with LDL-C in […]