A Systematic Review and Network Meta-analysis of Randomized Controlled Trials Nan Gao, MS Abstract Objective To compare the short-term effectiveness of corticosteroids, 5% dextrose (D5W), and platelet-rich plasma (PRP) injections for treating carpal tunnel syndrome (CTS). Data Sources Four databases (MEDLINE [PubMed], Embase, the Cochrane Controlled Trials Register, and Web of Science [WOS]) were researched […]
April 03, 2023 BMJ : British Medical Journal TAKE-HOME MESSAGE This pooled analysis examining more than 25,000 patients found a modest but significant reduction in the rates of incident CKD at follow-up (defined as new eGFR <60 mL/min/1.73 m2) among patients consuming higher levels of seafood-derived omega-3 fatty acids (EPA and DHA). The results showed […]
Ahorukomeye, Peter BSa,b; Mahajan, Arushi BSb; Du, Jerry Y. MDa; Yu, Charles C. MDc; Bhandutia, Amit K. MDd; Ahn, Nicholas U. MDa,b Spine 48(2):p 137-142, January 15, 2023. | DOI: 10.1097/BRS.0000000000004485 Abstract Study Design. Retrospective cross-sectional analysis. Summary of Background Data. Degenerative changes are a major contributor to chronic neck pain. According to the vascular […]
October 26, 2021 A Randomized Clinical Trial Liam D. A. Paget, MD JAMA. 2021;326(16):1595-1605. doi:10.1001/jama.2021.16602 Key Points Question Do intra-articular platelet-rich plasma injections improve ankle symptoms and function in patients with ankle osteoarthritis? Findings In this randomized clinical trial that included 100 patients, treatment with 2 intra-articular platelet-rich plasma injections vs placebo injections with saline resulted in […]
Archives of Physical Medicine and Rehabilitation VOLUME 102, ISSUE 5, P951-958, MAY 01, 2021 Si-Ru Chen, MD Abstract Objective To assess the therapeutic effect of platelet-rich plasma (PRP) for moderate-to-severe carpal tunnel syndrome (CTS). Design A prospective, randomized, double-blinded, controlled trial (1-year follow-up). Setting Outpatient of local medical center settings. Participants Patients (N=26) who were […]
August 19, 2020 JACC: Journal of the American College of Cardiology TAKE-HOME MESSAGE This study used data from 12,149 ARIC study participants to evaluate the relationship between two variables, elevated plasma Lp(a) and a family history (FHx) of coronary heart disease (CHD), and risk of atherosclerotic disease (ASCVD) and CHD over 21 years of follow-up. […]
— Different pattern seen in women, however, analysis finds by Nancy Walsh, Contributing Writer, MedPage Today June 4, 2020 A U-shaped relationship between serum urate levels and mortality was observed among U.S. men in a large cross-sectional survey, a researcher reported during the opening plenary abstract session at the European League Against Rheumatism (EULAR) virtual meeting. Among men […]
Archives of Physical Medicine and Rehabilitation Michael Catapano, MD VOLUME 101, ISSUE 5, P897-906, MAY 01, 2020 Highlights • Platelet-rich plasma (PRP) is theorized to reduce inflammation and promote neuronal and axon regeneration. • Four randomized controlled trials assessed the effects of PRP on pain and function in carpal tunnel syndrome. • PRP results in […]
— Odds ratios doubled for coronary artery calcification among men, but not women, with high serum urate levels by Nancy Walsh, Senior Staff Writer, MedPage Today February 25, 2020 High levels of serum urate were associated with the presence of coronary artery calcification in men, though not in women, Swedish researchers found. In a multivariate […]
J Cell Physiol. 2019 Aug;234(8):12581-12594. doi: 10.1002/jcp.28134. Epub 2019 Jan 13. Dietary natural products as emerging lipoprotein(a)-lowering agents Amir Abbas Momtazi-Borojeni PMID: 30637725 DOI: 10.1002/jcp.28134 Abstract Elevated plasma lipoprotein(a) (Lp(a)) levels are associated with an increased risk of cardiovascular disease (CVD). Hitherto, niacin has been the drug of choice to reduce elevated Lp(a) levels in […]
Benjamin J. Sherman, DO; Jorge Chahla, MD, PhD; Jason Glowney, MD; Rachel M. Frank, MD Orthopedics. 2019;42(2):66-73https://doi.org/10.3928/01477447-20190225-02 Posted March 21, 2019 Abstract Individuals with osteoarthritis have a diminished quality of life, and the condition is a major cause of disability. Newer biologic treatments have been developed that are believed to modify disease progression. These predominantly […]
International Journal of Rheumatic Diseases — Ahmad HS, et al. | June 01, 2018 Authors compared the effectiveness of platelet-rich plasma (PRP) and hyaluronic acid (HA) intra-articular injections as mono-therapeutic options for primary knee osteoarthritis (KOA). They also ascertained if the clinical outcomes were related to changes in the ultrasonography structural appearance. Findings suggested the […]
Di Yalong Arthritis Research & Therapy 2018 20:128 https://doi.org/10.1186/s13075-018-1621-0© The Author(s). 2018 Received: 16 September 2017Accepted: 13 May 2018 Published: 19 June 2018 Abstract Background In this study, we evaluated whether platelet-rich plasma (PRP) is superior to hyaluronic acid (HA) in the treatment of knee osteoarthritis. Methods The Cochrane Central Register of Controlled Trials, PubMed, […]
April 27, 2018 The American Journal of Sports Medicine TAKE-HOME MESSAGE The authors of this meta-analysis of 70 studies including 2530 participants evaluated the efficacy of the nonsurgical options for the treatment of patellar tendinopathy. The most-described treatments were eccentric exercise, extracorporeal shockwave therapy (ESWT), and single or multiple platelet-rich plasma (PRP) injections. The best […]
Patients may be experiencing placebo effect, but it’s still an effect, rheumatologist says by John Gever, Managing Editor, MedPage Today April 19, 2018 CHICAGO — In dealing with osteoarthritis, both patients and their physicians often have a hard time understanding what to make of novel “cures” such as platelet-rich plasma (PRP), stem cell treatments, and […]
January 31, 2018 Theingi Aung, MBBS, FRCP JAMA Cardiol. Published online January 31, 2018. doi:10.1001/jamacardio.2017.5205 Key PointsQuestion Does supplementation with marine-derived omega-3 fatty acids have any associations with reductions in fatal or nonfatal coronary heart disease in people at high risk of cardiovascular disease? Findings This meta-analysis of 10 trials involving 77 917 participants demonstrated that supplementation with marine-derived […]
International Journal of Rheumatic Diseases | December 08, 2017 Xing D, et al. – This study presents an overview of overlapping systematic reviews investigating platelet-rich plasma (PRP) for knee osteoarthritis (OA), wherein, methodological quality and risk of bias of systematic reviews were assessed and recommendations were offered via the best evidence. As per the evidence, without increasing […]
April 13, 2017 Clinical Rheumatology TAKE-HOME MESSAGE Participants adhering to either the Dietary Approaches to Stop Hypertension (DASH) diet or a control diet underwent repeated serum uric acid (SUA) measurement to evaluate the time required for the DASH diet to affect SUA levels. The participants following the DASH diet had a reduction in SUA of […]
Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. How secure should you feel if your doctor tells you that your cholesterol levels are normal Are you immune to heart disease just because you have been informed you have normal cholesterol levels? If you have been a reader of my weekly articles for any length of time, you […]
Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. Millions of Americans have been led to believe that osteoporosis is simply a deficiency of the common drugs, Boniva, Evista, Actonel, or Fosamax. Many are prescribed the “knee-jerk” recommendation of 1500 mgs of calcium a day to prevent osteoporosis. Unfortunately, nothing could be further from the truth. It is […]