Disc Degeneration

The association between cervical degenerative MRI findings and self-reported neck pain, disability and headache: a cross-sectional exploratory study

Rikke K. Jensen, Kristina B. Dissing, Tue S. Jensen, Stine H. Clausen & Bodil Arnbak Chiropractic & Manual Therapies volume 31, Article number: 45 (2023) Abstract Background Neck pain and headache are highly prevalent conditions and leading causes of disability worldwide. Although MRI is widely used in the management of these conditions, there is uncertainty […]

Association Between Hypercholesterolemia and Neck Pain in a Cross-sectional Population-based Study

Ahorukomeye, Peter BSa,b; Mahajan, Arushi BSb; Du, Jerry Y. MDa; Yu, Charles C. MDc; Bhandutia, Amit K. MDd; Ahn, Nicholas U. MDa,b Spine 48(2):p 137-142, January 15, 2023. | DOI: 10.1097/BRS.0000000000004485 Abstract Study Design. Retrospective cross-sectional analysis. Summary of Background Data. Degenerative changes are a major contributor to chronic neck pain. According to the vascular […]

A Case–control Study of Major Genetic Predisposition Risk Alleles in Developing DDD in the Northeast US Population: Effects of Gene–gene Interactions

Valtchinov, Vladimir I. PhD SPINE: November 15, 2021 – Volume 46 – Issue 22 – p 1525-1533 Study Design. A case–control study of risk alleles for degenerative disc disease (DDD) using magnetic resonance (MR) imaging for phenotyping. Objective. We aim to provide the first statistically adequately powered study of the relationship between the presence of […]

Lumbar spine intervertebral disc desiccation is associated with medical comorbidities linked to systemic inflammation

Published: 08 October 2021 Lambrechts, M.J., Pitchford, C., Hogan, D. et al. Lumbar spine intervertebral disc desiccation is associated with medical comorbidities linked to systemic inflammation. Arch Orthop Trauma Surg (2021). https://doi.org/10.1007/s00402-021-04194-3 Abstract Introduction Symptomatic disc degeneration is a common cause of low back pain. Recently, the prevalence of low back pain has swiftly risen […]

Chronology of disc degeneration and facet joint arthritis in lumbar spine is variable – A CT based cross-sectional study

J Orthop Sci. 2021 Aug 17;S0949-2658(21)00235-9. doi: 10.1016/j.jos.2021.07.016. Punit Tiwari PMID: 34412964 DOI: 10.1016/j.jos.2021.07.016 Abstract Background: The notion that disc degeneration (DD) always precedes facet joint arthritis (FJA) has held sway for many decades. However, it is not always the case. We hypothesized that DD is not always the first offender studied the prevalence of […]

Analysis of trends in lumbar disc degeneration using kinematic MRI

Clinical Imaging Volume 79, November 2021, Pages 136-141 Sidney Roberts Highlights • Lumbar disc degeneration increases in severity with age. • Men tend to degenerate at an earlier age than women. • The 5th decade of life is most common for people to develop severe degeneration. Abstract Objective The aim of the current study was […]

The effects of axial loading on the morphometric and T2 characteristics of lumbar discs in relation to disc degeneration

Clinical Biomechanics Volume 83, March 2021, 105291 Clinical Biomechanics VahidAbdollah Highlights • Effects of disc compression and traction measured using geometric and T2 centroids. • The largest responses to loading were observed at the lower lumbar levels. • The magnitude of responses to loading were associated with severity of disc degeneration. • T2 disc centroid, […]

Disc Degeneration of Young Low Back Pain Patients: A Prospective 30-year Follow-up MRI Study

Sääksjärvi, Simoa,b; Kerttula, Liisa MD, PhDc; Luoma, Katariina MD, PhDa,d; Paajanen, Hannu MD, PhDe; Waris, Eero MD, PhDa,bAuthor Information SPINE: October 1, 2020 – Volume 45 – Issue 19 – p 1341-1347 doi: 10.1097/BRS.0000000000003548 Study Design. A prospective follow-up study. Objective. The aim of this study was to investigate whether early lumbar disc degeneration (DD) […]

Disc height discrepancy between supine and standing positions as a screening metric for discogenic back pain in patients with disc degeneration

July 14, 2020 Seong Son, MD, Ph.D. The Spine Journal Published:July 17, 2020DOI:https://doi.org/10.1016/j.spinee.2020.07.006 Highlight The diagnosis of discogenic low back pain (LBP) in early to middle stage disc degeneration (Pfirrmann grade II, III, or IV) of the lumbar spine is ambiguous, unless a discography is performed. The disc height (DH) discrepancy ratio between supine and […]

Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration.

Med Sci Monit. 2019 Dec 14;25:9531-9537. doi: 10.12659/MSM.918649. NaPier Z. Abstract BACKGROUND Intervertebral disc (IVD) degeneration is a common cause of lower back pain, which carries substantial morbidity and economic cost. Omega-3 fatty acids (n-3 FA) are known to reduce inflammatory processes with a relatively benign side effect profile. This study aimed to investigate the […]

Ten-year Longitudinal Follow-up MRI Study of Age-related Changes in Thoracic Intervertebral Discs in Asymptomatic Subjects

Spine: November 15, 2019 – Volume 44 – Issue 22 – p E1317-E1324 doi: 10.1097/BRS.0000000000003145 Okada, Eijiro MD, PhD Study Design. Prospective longitudinal study. Objective. The aim of this study was to evaluate long-term degenerative changes in intervertebral discs in the thoracic spine in healthy asymptomatic subjects. Summary of Background Data. Longitudinal magnetic resonance imaging (MRI) […]

Differential Patient Responses to Spinal Manipulative Therapy and Their Relation to Spinal Degeneration and Post-Treatment Changes in Disc Diffusion

Eur Spine J. 2019 Feb;28(2):259-269. doi: 10.1007/s00586-018-5851-2. Epub 2019 Jan 2. Arnold Y L Wong 1 2, Eric C Parent 3, Sukhvinder S Dhillon 4, Narasimha Prasad 5, Dino Samartzis 6, Gregory N Kawchuk 3 PMID: 30604298 DOI: 10.1007/s00586-018-5851-2 Abstract Purpose: Our prior study revealed that people with non-specific low back pain (LBP) who self-reported […]

Severe lumbar intervertebral disc degeneration is associated with Modic changes and fatty infiltration in the paraspinal muscles at all lumbar levels, except L1-L2: A cross-sectional analysis of 50 symptomatic females and age-matched 50 symptomatic males

World Neurosurgery Available online 9 November 2018 Severe lumbar intervertebral disc degeneration is associated with Modic changes and fatty infiltration in the paraspinal muscles at all lumbar levels, except L1-L2: A cross-sectional analysis of 50 symptomatic females and age-matched 50 symptomatic males EmelEce Özcan-Ekş iM.D. Abstract Objective Low back pain is a common public health […]

ABCs of the degenerative spine – Full Text Article

Insights Imaging. 2018 Apr; 9(2): 253–274. Published online 2018 Mar 22. doi: 10.1007/s13244-017-0584-z PMCID: PMC5893484 PMID: 29569215 Sergiy V. Kushchayev Abstract Degenerative changes in the spine have high medical and socioeconomic significance. Imaging of the degenerative spine is a frequent challenge in radiology. The pathogenesis of this degenerative process represents a biomechanically related continuum of […]

Lumbar disc nomenclature: version 2.0: Recommendations of the combined task forces of the North American Spine Society, the American Society of Spine Radiology and the American Society of Neuroradiology – Full Text

The Spine Journal Volume 14, Issue 11, 1 November 2014, Pages 2525-2545 David F.Fardon MD Abstract Background context The paper ‘‘Nomenclature and classification of lumbar disc pathology, recommendations of the combined task forces of the North American Spine Society, the American Society of Spine Radiology and the American Society of Neuroradiology,’’ was published in 2001 […]

In vivo correlates between daily physical activity and intervertebral disc health.

J Orthop Res. 2018 May;36(5):1313-1323. doi: 10.1002/jor.23765. Epub 2018 Jan 16. Bowden JA1, Bowden AE2, Wang H3, Hager RL1, LeCheminant JD1, Mitchell UH1. Abstract Physical activity impacts health and disease in multiple body tissues including the intervertebral discs. Fluid flow within the disc is an indicator of disc health that can be observed using diffusion […]

The Association Between Self-reported Low Back Pain and Radiographic Lumbar Disc Degeneration of the Cohort Hip and Cohort Knee (CHECK) Study

van den Berg, Roxanne M Spine: 1 October 2017 – Volume 42 – Issue 19 – p 1464–1471 doi: 10.1097/BRS.0000000000002228 Study Design. Cross-sectional study, nested in a prospective cohort (Cohort Hip and Knee, CHECK). Objective. Low back pain (LBP) is very common and the main cause of activity limitations and work absence throughout the world. […]

Spinal mobilization vs conventional physiotherapy in the management of chronic low back pain due to spinal disk degeneration: a randomized controlled trial

J Man Manip Ther. 2017 May;25(2):66-73. doi: 10.1080/10669817.2016.1184435. Epub 2016 Jun 23. Krekoukias G Abstract OBJECTIVES: The aim of the study was to examine the efficacy of spinal mobilization in subjects with low back pain (LBP) and associated spinal disk degeneration. METHODS: Seventy-five subjects suffering from chronic LBP (>3 months) were randomly allocated into 3 groups of […]

Uneven intervertebral motion sharing is related to disc degeneration and is greater in patients with chronic, non-specific low back pain – Full Text Article

European Spine Journal pp 1–9 Uneven intervertebral motion sharing is related to disc degeneration and is greater in patients with chronic, non-specific low back pain: an in vivo, cross-sectional cohort comparison of intervertebral dynamics using quantitative fluoroscopy Authors Alan Breen Cite this article as: Breen, A. & Breen, A. Eur Spine J (2017). doi:10.1007/s00586-017-5155-y Abstract […]

Association of Mild Leg Length Discrepancy and Degenerative Changes in the Hip Joint and Lumbar Spine

J Manipulative Physiol Ther. 2017 Apr 17. pii: S0161-4754(17)30065-9. doi: 10.1016/j.jmpt.2017.03.001. [Epub ahead of print] Murray KJ1, Molyneux T1, Le Grande MR2, Castro Mendez A3, Fuss FK4, Azari MF5. Author information Abstract OBJECTIVE: The purpose of this study was to evaluate the correlation between mild leg length discrepancy (LLD) and degenerative joint disease (DJD) or […]