Eicosapentaenoic acid (EPA)

Migraine Frequency, Severity Drop Substantially With Diet Interventions

— Findings could lead to targeted dietary changes to improve chronic pain by Judy George, Senior Staff Writer, MedPage Today June 30, 2021 A diet higher in two omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), reduced headache frequency and intensity and lowered levels of pain-related lipids in migraine patients, a randomized controlled trial showed. […]

Migraine Frequency, Severity Drop Substantially With Diet Interventions

— Findings could lead to targeted dietary changes to improve chronic pain by Judy George, Senior Staff Writer, MedPage Today June 30, 2021 A diet higher in two omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), reduced headache frequency and intensity and lowered levels of pain-related lipids in migraine patients, a randomized controlled trial showed. […]

Omega-3 Fatty Acid Supplementation Reduces Intervertebral Disc Degeneration.

Med Sci Monit. 2019 Dec 14;25:9531-9537. doi: 10.12659/MSM.918649. NaPier Z. Abstract BACKGROUND Intervertebral disc (IVD) degeneration is a common cause of lower back pain, which carries substantial morbidity and economic cost. Omega-3 fatty acids (n-3 FA) are known to reduce inflammatory processes with a relatively benign side effect profile. This study aimed to investigate the […]

Lower Fatty Acid Levels in Pregnancy May Up Early Preterm Birth Risk

Findings support fish intake, supplements to prevent early preterm birth by Molly Walker, Staff Writer, MedPage Today August 04, 2018 Danish women with low plasma concentrations of the long-chain fatty acids eicosapentaenoic acid plus docosahexaenoic acid (EPA+DHA) during pregnancy had a higher risk of subsequent preterm birth, researchers found. Pregnant women in the lowest quintile […]

A meta-analysis of randomized controlled trials and prospective cohort studies of eicosapentaenoic and docosahexaenoic long-chain omega-3 fatty acids and coronary heart disease risk

Mayo Clinic Proceedings, 01/17/2017 Alexander DD, et al. The target of this study was to assess the impact of eicosapentaenoic and docosahexaenoic acid (EPA+DHA) on coronary heart disease (CHD), and to lead meta–analyses of prospective cohort studies to estimate the association between EPA+DHA consumption and CHD risk. Outcomes show that EPA+DHA might be connected with […]

Consumption of fish oil providing amounts of EPA and DHA that can be obtained from the diet reduces blood pressure in adults with systolic hypertension: a retrospective analysis

The Journal of Nutrition, 02/05/2016 Minihane AM, et al. – The objective was to examine, by using a retrospective analysis from a multicenter RCT, the impact of recommended EPA+DHA intakes achievable through diet on systolic and diastolic BPs and microvascular function in adults in the United Kingdom. The findings indicate that in adults with isolated […]

Higher Dose Fish Oil, an Effective Thermogenic for Older Women

Friday, January 15, 2016 I am not exactly a fan of fish oil supplementation, but I am neither ignoring the few gems among the bazillion of “fish oil is good for you” papers. Samantha L. Logan’s and Lawrence L. Spriet’s latest paper in the open access journalPLOS|ONE looks as if it was one of those gems. A […]

PUFA, Linoleic Acid, EPA and DHA Inversely Associated with All-Cause Mortality and Incident CVD

Polyunsaturated Fat Intake Estimated by Circulating Biomarkers and Risk of Cardiovascular Disease and All-Cause Mortality in a Population-Based Cohort of 60-Year-Old Men and Women Matti Marklund CIRCULATIONAHA.115.015607 Published online before print June 17, 2015, doi: 10.1161/CIRCULATIONAHA.115.015607 Abstract Background—High intake of polyunsaturated fatty acids (PUFA) may reduce the risk of cardiovascular disease (CVD) and mortality. Large […]

Exercise Enhances Omega 3’s Benefits In Reducing CVD Events In Midlife

Concurrent physical activity modifies the association between n3 long-chain fatty acids and cardiometabolic risk in midlife adults. Muldoon MF, et al. J Nutr. 2013. Show full citation Abstract Greater consumption of n3 (ω3) polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can reduce risk for cardiovascular disease events, yet their effects on metabolic […]

Extra EPA and DHA may Relieve Key Symptoms in Kids with ADHD

Date Posted: 2/5/2015 4:45:18 PM Children with attention-deficit hyperactivity disorder (ADHD) who increase their levels of both the DHA and EPA found in omega-3 fatty acids may have better attention spans, literacy rates and behavior, according to an Australian study. In a study published in November 2013 in the Journal of Attention Disorders,researchers from the University of South […]

A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells

A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells Carcinogenesis, 09/25/2014 Clinical Article D’Angelo L, et al. – The aim of this study was to explore the effect of a combination of three natural compounds, eicosapentaenoic acid–free fatty acid, epigallocatechin–3–gallate and proanthocyanidins at […]

Omega-3 fatty acid is a potential preventive agent for recurrent colon cancer

Cancer Prevention Research, 09/12/2014 Clinical Article Vasudevan A, et al. – The primary objectives of this investigation are to examine whether eicosapentaenoic acid synergizes with FuOx, the backbone of colon cancer chemotherapy, and (b) whether EPA by itself or in combination with conventional chemotherapy prevents the recurrence of colon cancer via eliminating/suppressing CSCs/CSLCs. The data […]

Omega-3 Fatty acids for postoperative atrial fibrillation: alone or in combination with antioxidant vitamins?

Omega-3 Fatty acids for postoperative atrial fibrillation: alone or in combination with antioxidant vitamins? Guo, XY Heart Lung Circ. 2014 Aug;23(8):743-50. doi: 10.1016/j.hlc.2014.02.018. Epub 2014 Mar 12 Abstract BACKGROUND: The effects of omega-3 polyunsaturated fatty acids (PUFA) on the prevention of postoperative atrial fibrillation (POAF) are inconclusive in current studies. Moreover, the most appropriate composition […]

A new piece in the puzzling effect of n-3 fatty acids on atherosclerosis

Atherosclerosis, 05/23/2014 Clinical Article Le Goff W – Omega–3 fatty acids (n–3) FA are reported to be protective against cardiovascular disease (CVD), notably through their beneficial action on atherosclerosis development. In this context dietary intake of long–chain marine eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is recommended and randomized trials largely support that EPA and […]

New Study Suggests Combination of Statin and Omega-3 Fatty Acid May Provide Cardioprotective Effects

Brigham & Women’s Hospital Boston, MA– New findings from an in vitro study, led by researchers at Brigham and Women’s Hospital (BWH), show that the combination of statins and eicosapentaenoic acid (EPA), an omega-3 fatty acid, may potentially reduce cardiovascular risk. This research is being presented May 1 at a peer-reviewed poster session at the […]

Treatment of rheumatoid arthritis with marine and botanical oils

Randomized, and double-blind trial Evidence-based Complementary and Alternative Medicine , 03/25/2014  Clinical Article Reed GW, et al. – The study aims to determine whether a combination of borage seed oil rich in gamma linolenic acid (GLA) and fish oil rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is superior to either oil alone for treatment of rheumatoid […]

Omega-3 Fatty Acids for Postoperative Atrial Fibrillation: Alone or in Combination with Antioxidant Vitamins?

Xue-Yuan Guo, MD Heart, Lung and Circulation Available online 12 March 2014 Background The effects of omega-3 polyunsaturated fatty acids (PUFA) on the prevention of postoperative atrial fibrillation (POAF) are inconclusive in current studies. Moreover, the most appropriate composition of PUFA to play the protective role is unclear. The aim of this meta-analysis was to […]

Higher combined intake of EPA acid and DHA from diet and supplements was associated with a decreased risk of total mortality

The objective was to evaluate whether intake of long–chain ω–3 fatty acids from diet and supplements is associated with cause–specific and total mortality. The results suggest that intake of long–chain ω–3 fatty acids may reduce risk of total and cancer–specific mortality. Methods Study participants (n = 70,495) were members of a cohort study (the Vitamins […]

High Omega-3 PUFA Intake Reduces Type 2 Diabetes Risk

Becky McCall January 22, 2014 Full Story A higher level of serum long-chain omega-3 polyunsaturated fatty acids (PUFAs) — an objective biomarker of fish intake — is linked to a lower long-term risk for type 2 diabetes, according to the results of a new prospective, population-based cohort study. Among dietary factors, the long-chain omega-3 PUFAs, […]

Evidence-Based Supplement Use in Macular Degeneration: The AREDS Studies (Part 1)

Interview December 05, 2013 Stuart P Richer OD, PhD Kathy F Freeman OD, FAAO Full Story:  http://www.practiceupdate.com/expertopinion/651 Dr. Stuart Richer speaks with Dr. Kathy Freeman of PracticeUpdate about the effects of supplements on the prevention of ocular disease. In Part 1, Dr. Richer discusses the results of the AREDS trials. In Part 2, he goes […]