Platelet Rich Plasma

Comparison of the Short-Term Clinical Effectiveness of 5% Dextrose Water, Platelet-rich Plasma and Corticosteroid Injections for Carpal Tunnel Syndrome

A Systematic Review and Network Meta-analysis of Randomized Controlled Trials Nan Gao, MS Abstract Objective To compare the short-term effectiveness of corticosteroids, 5% dextrose (D5W), and platelet-rich plasma (PRP) injections for treating carpal tunnel syndrome (CTS). Data Sources Four databases (MEDLINE [PubMed], Embase, the Cochrane Controlled Trials Register, and Web of Science [WOS]) were researched […]

One-Year Efficacy of Platelet-Rich Plasma for Moderate-to-Severe Carpal Tunnel Syndrome: A Prospective, Randomized, Double-Blind, Controlled Trial

Archives of Physical Medicine and Rehabilitation VOLUME 102, ISSUE 5, P951-958, MAY 01, 2021 Si-Ru Chen, MD Abstract Objective To assess the therapeutic effect of platelet-rich plasma (PRP) for moderate-to-severe carpal tunnel syndrome (CTS). Design A prospective, randomized, double-blinded, controlled trial (1-year follow-up). Setting Outpatient of local medical center settings. Participants Patients (N=26) who were […]

Effectiveness of Platelet-Rich Plasma Injections for Nonsurgical Management of Carpal Tunnel Syndrome: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Archives of Physical Medicine and Rehabilitation Michael Catapano, MD VOLUME 101, ISSUE 5, P897-906, MAY 01, 2020 Highlights •  Platelet-rich plasma (PRP) is theorized to reduce inflammation and promote neuronal and axon regeneration. •  Four randomized controlled trials assessed the effects of PRP on pain and function in carpal tunnel syndrome. •  PRP results in […]

The Role of Orthobiologics in the Management of Osteoarthritis and Focal Cartilage Defects

Benjamin J. Sherman, DO; Jorge Chahla, MD, PhD; Jason Glowney, MD; Rachel M. Frank, MD Orthopedics. 2019;42(2):66-73https://doi.org/10.3928/01477447-20190225-02 Posted March 21, 2019 Abstract Individuals with osteoarthritis have a diminished quality of life, and the condition is a major cause of disability. Newer biologic treatments have been developed that are believed to modify disease progression. These predominantly […]

Clinical outcomes are associated with changes in ultrasonographic structural appearance after platelet-rich plasma treatment for knee osteoarthritis

International Journal of Rheumatic Diseases — Ahmad HS, et al. | June 01, 2018 Authors compared the effectiveness of platelet-rich plasma (PRP) and hyaluronic acid (HA) intra-articular injections as mono-therapeutic options for primary knee osteoarthritis (KOA). They also ascertained if the clinical outcomes were related to changes in the ultrasonography structural appearance. Findings suggested the […]

Is local platelet-rich plasma injection clinically superior to hyaluronic acid for treatment of knee osteoarthritis? A systematic review of randomized controlled trials

Di Yalong Arthritis Research & Therapy 2018 20:128 https://doi.org/10.1186/s13075-018-1621-0© The Author(s). 2018 Received: 16 September 2017Accepted: 13 May 2018 Published: 19 June 2018 Abstract Background In this study, we evaluated whether platelet-rich plasma (PRP) is superior to hyaluronic acid (HA) in the treatment of knee osteoarthritis. Methods The Cochrane Central Register of Controlled Trials, PubMed, […]

Multiple Injections of Platelet-Rich Plasma for Patellar Tendinopathy

April 27, 2018 The American Journal of Sports Medicine TAKE-HOME MESSAGE The authors of this meta-analysis of 70 studies including 2530 participants evaluated the efficacy of the nonsurgical options for the treatment of patellar tendinopathy. The most-described treatments were eccentric exercise, extracorporeal shockwave therapy (ESWT), and single or multiple platelet-rich plasma (PRP) injections. The best […]

Respect the Needle in Osteoarthritis

Patients may be experiencing placebo effect, but it’s still an effect, rheumatologist says by John Gever, Managing Editor, MedPage Today April 19, 2018 CHICAGO — In dealing with osteoarthritis, both patients and their physicians often have a hard time understanding what to make of novel “cures” such as platelet-rich plasma (PRP), stem cell treatments, and […]

Intra-articular platelet-rich plasma injections for knee osteoarthritis: An overview of systematic reviews and risk of bias considerations

International Journal of Rheumatic Diseases | December 08, 2017 Xing D, et al. – This study presents an overview of overlapping systematic reviews investigating platelet-rich plasma (PRP) for knee osteoarthritis (OA), wherein, methodological quality and risk of bias of systematic reviews were assessed and recommendations were offered via the best evidence. As per the evidence, without increasing […]

Platelet-Rich Plasma Superior to Corticosteroid Injection for Lumbar Facet Joint Syndrome

Autologous platelet-rich plasma efficacious for a longer duration than LA/corticosteroid WEDNESDAY, Dec. 28, 2016 (HealthDay News) — For intra-articular injection autologous platelet-rich plasma (PRP) and local anesthetic (LA)/corticosteroid are effective, easy, and safe in the treatment of lumbar facet joint syndrome, according to a study published online Dec. 18 in Pain Practice. Jiuping Wu, from […]

Randomized controlled trial comparing hyaluronic acid, platelet-rich plasma and the combination of both in the treatment of mild and moderate osteoarthritis of the knee

Lana JFSD Abstract Objective: This study aims to evaluate the clinical effects of Platelet Rich Plasma (PRP) and Hyaluronic Acid (HA) as individual treatments for mild to moderate Osteoarthritis (OA), and also examine the potential synergistic effects of PRP in combination with HA. Research continues to emerge examining the potential therapeutic efficacy of HA and […]

Improvement in Knee Osteoarthritis Pain With Platelet-Rich Plasma Injections Lasts for 6 Months

March 07, 2016 February 21, 2016—Palm Springs, California—The beneficial clinical effects of platelet-rich plasma injections for knee osteoarthritis pain remained stable from the end of treatment through 6 months follow up in most studies of the technique. This outcome of a systematic review encompassing 24 studies was presented at the 32nd Annual Meeting of the […]

Chronic Plantar Fasciitis: Effect of Platelet-Rich Plasma, Corticosteroid, and Placebo

Pankaj Mahindra, MS; Mohammad Yamin, MS; Harpal S. Selhi, MS; Sonia Singla, MD; Ashwani Soni, MS Orthopedics Posted February 25, 2016 DOI: 10.3928/01477447-20160222-01 Abstract Plantar fasciitis is a common cause of heel pain. It is a disabling disease in its chronic form. It is a degenerative tissue condition of the plantar fascia rather than an […]

PRP may be superior to hyaluronic acid for improvement of pain, function in patients with OA

April 27, 2015 LOS ANGELES — Use of intra-articular platelet-rich plasma significantly improved pain and function in patients with osteoarthritis at 6 months and may be a superior alternative to hyaluronic acid, according to study findings presented at the Arthroscopy Association of North America Annual Meeting. “Our study suggests that lower-leukocyte [platelet-rich plasma] is … […]