C-Reactive Protein

Relationship between systemic inflammation and recovery over 12 months after an acute episode of low back pain

The Spine Journal VOLUME 22, ISSUE 2, P214-225, FEBRUARY 01, 2022 Highlights •  Early transiently raised C-reactive protein associated with good long-term recovery after acute back pain. •  Persistent tumor necrosis factor overexpression associated with poor long-term recovery after acute back pain. •  Psychological and sleep status during acute back pain did not predict future […]

The effects of curcumin-containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials.

Phytother Res. 2019 Feb;33(2):253-262. doi: 10.1002/ptr.6226. Epub 2018 Nov 7. Tabrizi R1, Vakili S2, Akbari M1, Mirhosseini N3, Lankarani KB1, Rahimi M4, Mobini M5, Jafarnejad S6, Vahedpoor Z7, Asemi Z6. Abstract Besides other benefits, curcumin is getting more recognized for its antioxidant and anti-inflammatory properties, highlighting the importance of curcumin application for chronic disease prevention. […]

Exploration of the Inter-Relationships Between Obesity, Physical Inactivity, Inflammation, and Low Back Pain

Hashem, Lukas E., BSc Spine: September 1, 2018 – Volume 43 – Issue 17 – p 1218-1224 doi: 10.1097/BRS.0000000000002582 Study Design. Retrospective analysis wherein 103 patients were considered, and 76 patients were included: 49 were classified as chronic non-specific low back pain (CNSLBP) (Study group) and 27 had identifiable cases of specific chronic low back pain (LBP) (Control […]

Adherence to Mediterranean diet, high-sensitive C-reactive protein, and severity of coronary artery disease: Contemporary data from the INTERCATH cohort

Atherosclerosis August 2018 Volume 275, Pages 256–261 Christoph Waldeyer Highlights •The guidelines strongly recommend a healthy diet as a cornerstone of cardiovascular disease prevention. •An association with Mediterranean diet (MD) has been shown for different vascular beds. •There are no multivariate data regarding Mediterranean diet and the extent of coronary artery disease (CAD). •The present […]

Study identifies a link between antidepressant treatment resistance and inflammation

Woodruff Health Sciences Center | June 7, 2018 Researchers at Emory University have found that depressed patients who have not responded to multiple antidepressants exhibit evidence of increased inflammation. Findings were recently published online in the journal, Psychoneuroendocrinology. The study shows that antidepressant treatment resistance is associated with increased inflammatory markers in patients with depression. […]

Effects of long-term consumption of broccoli sprouts on inflammatory markers in overweight subjects

Clin Nutr. 2018 Mar 13. pii: S0261-5614(18)30118-3. doi: 10.1016/j.clnu.2018.03.006. [Epub ahead of print] López-Chillón MT Abstract BACKGROUND & AIMS: Broccoli sprouts represent an interesting choice of healthy food product as they are rich in glucosinolates and their cognate bioactive metabolites, isothiocyanates able to counteract the negative effects of diverse pathologies. As obesity is linked to […]

Reducing inflammation without lowering cholesterol cuts risk of cardiovascular events

Inflammatory hypothesis confirmed: Landmark randomized clinical trial of high-risk patients finds that a drug targeting inflammation reduced risk of major adverse cardiovascular events Date: August 28, 2017 Source: Brigham and Women’s Hospital Summary: Investigators have announced results of a clinical trial culminating from 25 years of cardiovascular research work. The team reports a significant reduction […]

Chlamydia and Heart Disease

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. How secure should you feel if your doctor tells you that your cholesterol levels are normal? Are you immune to heart disease just because you have been informed you have normal cholesterol levels? If you have been a reader of my weekly articles for any length of time, you […]

Association Between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes

May 15, 2017 Journal of Investigative Dermatology TAKE-HOME MESSAGE This retrospective analysis of 1804 melanoma patients from 1998 to 2008 investigated the effect of body mass index (BMI) and C-reactive protein levels on melanoma outcomes. Increased BMI was associated with lower overall and melanoma-specific survival. Increased BMI was also associated with lower overall and melanoma-specific […]

Chlamydia and Heart Disease

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. How secure should you feel if your doctor tells you that your cholesterol levels are normal Are you immune to heart disease just because you have been informed you have normal cholesterol levels? If you have been a reader of my weekly articles for any length of time, you […]

Obesity May Increase Cognitive Decline via Inflammation

Liam Davenport October 24, 2016 Being overweight or obese leads to clinically meaningful increases in the rate of cognitive decline in association with changes in inflammatory markers in the blood, a new analysis of longitudinal data suggests. The results, which indicate that an increased body mass index (BMI) may accelerate cognitive decline by several months […]

Functions of Coenzyme Q10 Supplementation on Liver Enzymes, Markers of Systemic Inflammation, and Adipokines in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial.

J Am Coll Nutr. 2016 May-Jun;35(4):346-53. doi: 10.1080/07315724.2015.1021057. Epub 2015 Jul 9. Farsi F1, Mohammadshahi M1, Alavinejad P2, Rezazadeh A3, Zarei M4, Engali KA5. Abstract BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disorder related to inflammation. Coenzyme Q10 (CoQ10) is a natural compound that has recently been considered as an anti-inflammatory factor. […]

Garlic and heart disease

The Journal of Nutrition, 01/29/2016 Varshney R, et al. Researchers sought to assess the effects of garlic supplements on hypertension, hypercholesterolemia, C–reactive protein (CRP), pulse wave velocity (PWV), and coronary artery calcium (CAC), as well as available data on adverse reactions. They found that garlic supplementation may offer cardiovascular protection. Methods Researchers searched PubMed for […]

New National Guidelines Discuss Measuring Inflammatory Biomarkers to Identify Increased Stroke Risk

Posted on January 21, 2015 by Cleveland HeartLab The American Heart Association/American Stroke Association (AHA/ASA) just published new guidelines for the primary prevention of stroke that acknowledge the relationship between inflammation and various stages of the atherogenic process including initiation, progression, and stability of atherosclerotic lesions.  They reference a number of studies that show associations […]

Inflammation Tied to Bone Marrow Lesions in Knee OA

01.20.2016 Results may facilitate development of new treatment strategies by Wayne Kuznar Contributing Writer Systemic inflammation was linked with bone marrow lesion scores and pain in patients with knee osteoarthritis (OA), researchers from Australia and China reported. Serum high sensitivity-C-reactive protein (hs-CRP) was associated with the presence of knee bone marrow lesions and knee pain, […]

Fish oil supplementation does not lower C-reactive protein or interleukin-6 levels in healthy adults

Journal of Internal Medicine, 11/03/2015 Muldoon MF, et al. The n–3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may prevent a range of chronic conditions through anti–inflammatory actions. However, as clinical trials using these fatty acids for primary prevention are yet unavailable, their putative role in disease prevention rests, in part, on […]

It is time to stop counting calories, and time instead to promote dietary changes that substantially and rapidly reduce cardiovascular morbidity and mortality

Open Heart 2015;2: doi:10.1136/openhrt-2015-000273 Editorial It is time to stop counting calories, and time instead to promote dietary changes that substantially and rapidly reduce cardiovascular morbidity and mortality Aseem Malhotra1, James J DiNicolantonio3and Simon Capewell Most heart attacks and ischaemic strokes are caused by complicated atheroma usually compounded by thrombosis suddenly reducing blood flow in […]

Inflammation, not telomere length, predicts healthy longevity of centenarians

August 5, 2015 Scientists have cracked the secret of why some people live a healthy and physically independent life over the age of 100. For the first time, a team of experts from Newcastle University’s Institute for Ageing and Keio University School of Medicine, Tokyo, explored which biological and pathological processes may be the most […]

Importance of C-Reactive Protein (High Sensitivity)

A few months ago a story in The New York Times revealed the newly discovered importance of high sensitivity C-reactive protein (CRP). Apparently, a drug company-sponsored study showed that people who had high CRP levels had fewer heart attacks and strokes when taking statins (cholesterol-lowering drugs). Suddenly, the whole medical community is buzzing about the […]

Study Flags Alkaline Phosphatase Levels as Bone Risk in Axial Spondyloarthritis

4/10/15 by Wayne Kuznar Contributing Writer In patients with axial spondyloarthritis (SpA), increased serum alkaline phosphatase (ALP) levels not only reflect high disease activity but also low bone mineral density (BMD) and structural damage, according to a cross-sectional study by South Korean researchers. The need for biomarkers that reflect both disease activity and bone metabolism […]