Anti-depressants

Do antidepressants work better than placebo?

Do antidepressants work better than placebo? Published Thursday 18 July 2019 By Tim Newman Scientists have been debating the efficacy of antidepressants for decades. The latest paper to throw its hat into the ring concludes that there is little evidence to show that they perform better than placebos. In 2017, around 17.3 million adults in the United […]

Many People Taking Antidepressants Discover They Cannot Quit

By BENEDICT CAREY and ROBERT GEBELOFF APRIL 7, 2018 Victoria Toline would hunch over the kitchen table, steady her hands and draw a bead of liquid from a vial with a small dropper. It was a delicate operation that had become a daily routine — extracting ever tinier doses of the antidepressant she had taken […]

Antidepressant Use Linked to Increased Brain Bleed Risk

Nancy A. Melville January 12, 2016 Use of antidepressants is linked to an increased risk for the development of first-time cerebral microbleeds, results of a longitudinal study show. “In this population-based study, we found that antidepressant use was associated with an increased risk of incident first-ever microbleeds after 4 years of follow-up,” the authors, led […]

Antidepressant/NSAID Combo Linked to Brain Bleed Risk

Nancy A. Melville July 14, 2015 The combination of antidepressants and nonsteroidal anti-inflammatory drugs (NSAIDS) is linked to an early increased risk for intracranial hemorrhage, regardless of the type of NSAID or antidepressant, new research shows. “The take-home message for clinicians is that special attention should be paid [to] antidepressant users when they start an […]

Antidepressants Blunt Sexual Function, Feelings of Love

Medscape Medical News from the: 27th European College of Neuropsychopharmacology (ECNP) Congress Medscape Medical News > Psychiatry Antidepressants Blunt Sexual Function, Feelings of Love Deborah Brauser October 20, 2014 BERLIN ― Long-term antidepressant use may be associated with significant “emotional blunting” in both male and female patients ― but in different ways, new research suggests. […]

Emergency Department Visits by Adults for Psychiatric Medication Adverse Events

PracticeUpdate RESEARCH · July 09, 2014 TAKE-HOME MESSAGE This study used data from the National Electronic Injury Surveillance System–Cooperative Adverse Drug Event Surveillance system to estimate the number of adverse drug events (ADEs) involving psychiatric medications among US adults resulting in emergency department (ED) visits. Annually from 2009 to 2011, there were nearly 90,000 ED […]

Prenatal SSRI Use May Increase Autism Risk

Research · April 14, 2014 TAKE-HOME MESSAGE In 966 mother–child pairs, including children with autism spectrum disorders (ASDs), developmental delays (DDs), and typical development (TD), boys with ASD were three times more likely than children with TD to have been prenatally exposed to selective serotonin reuptake inhibitors (SSRIs), and children with DDs were also more […]

Anti-Anxiety Drugs Tied to Higher Mortality

By NICHOLAS BAKALAR MARCH 27, 2014, 3:57 PM A large study has linked several common anti-anxiety drugs and sleeping pills to an increased risk of death, although it’s not certain the drugs were the cause. For more than seven years, researchers followed 34,727 people who filled prescriptions for anti-anxiety medications like Valium and Xanax, or […]

New test suggests antidepressant Paxil may promote breast cancer

by Melissa Healy February 15, 2014 A team of researchers from the City of Hope in Duarte has developed a speedy way to identify drugs and chemicals that can disrupt the balance of sex hormones in human beings and influence the development and progress of diseases such as breast cancer. In a trial screening of […]

Antidepressants in the Treatment for Chronic Low Back Pain

Questioning the Validity of Meta-Analyses Williamson, O. D., Sagman, D., Bruins, R. H., Boulay, L. J. and Schacht, A. (2013), Antidepressants in the Treatment for Chronic Low Back Pain: Questioning the Validity of Meta-Analyses. Pain Practice. doi: 10.1111/papr.12119 Disclosures: This research was funded by Eli Lilly and Company. Abstract Objectives To contrast the analgesic effect […]

Antidepressants, Lyrica OK Combo in Fibromyalgia

Published: Nov 1, 2013 By Nancy Walsh, Staff Writer, MedPage Today Full Story:  http://www.medpagetoday.com/MeetingCoverage/ACR/42653 Action Points Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. SAN DIEGO — Patients with fibromyalgia who were taking […]

Drugs for relief of pain in patients with sciatica

Systematic review and meta-analysis Rafael Zambelli Pinto, PhD student BMJ 2012; 344 doi: http://dx.doi.org/10.1136/bmj.e497 (Published 13 February 2012) Cite this as: BMJ 2012;344:e497 Abstract Objective To investigate the efficacy and tolerability of analgesic and adjuvant pain drugs typically administered in primary care for the management of patients with sciatica. Design Systematic review. Data source International […]

A systematic review on the effectiveness of pharmacological interventions for chronic non-specific low-back pain

T. Kuijpers European Spine Journal January 2011, Volume 20, Issue 1, pp 40-50 First online: 31 July 2010 Abstract The objective of this review was to determine the effectiveness of pharmacological interventions [i.e., non-steroid anti-inflammatory drugs (NSAIDs), muscle relaxants, antidepressants, and opioids] for non-specific chronic low-back pain (LBP). Existing Cochrane reviews for the four interventions […]