December 1, 2014 Alisa G. Woods, PhD Pain relief is better with a triple combination medication that includes acetaminophen than with acetaminophen by itself, researchers found, suggesting a new therapeutic option. A triple combination medication for tension headache that includes acetaminophen is more effective for pain relief than acetaminophen by itself, an international group of […]
Luepker RV, Oldenburg NC, Misialek JR, et al American Journal of Preventive Medicine | February 4, 2021 This study was sought to present the prevalence of appropriate aspirin use and physician advice in a population sample using the Task Force recommendations. Between 2017 and 2018, a random sample of men and women (aged 50–69 years) […]
BMJ Open — Barker AL, Soh SE, Sanders KM, et al. | February 25, 2020 A systematic review and exploratory meta-analysis of observational studies were conducted to provides insights into the potential for aspirin to preserve bone mineral density (BMD) and reduce fracture risk, building knowledge of the risk-benefit profile of aspirin. A systematic review […]
BMC Medicine — Gelbenegger G, Postula M, Pecen L, et al. | November 14, 2019 Thirteen randomized, controlled trials on the effect of aspirin for primary prevention of CVD vs control were included in this meta-analysis to examine the benefit-risk ratio of aspirin for primary prevention of CVD with a special focus on subgroups. Researchers […]
Reuters Health News | May 14, 2019 For people without heart disease, taking a daily aspirin to prevent heart attacks and strokes may increase the risk of severe intracranial bleeding to the point where the risk outweighs any potential benefit, a research review suggests. US doctors have long advised adults who haven’t had a heart […]
Sue Hughes January 23, 2019 A new meta-analysis of trials evaluating aspirin for primary prevention of cardiovascular disease has found no overall benefit, with aspirin use associated with a lower risk of cardiovascular events but an increased risk of major bleeding, and no effect of aspirin on cancer risk. However, there still appears to be some disagreement […]
The Lancet — Rothwell PM, et al. | July 20, 2018 In view of only modest benefits of a one-dose-fits-all approach to aspirin use for long-term prevention of cardiovascular events, researchers assessed aspirin in primary prevention of cardiovascular events by analyzing the modifying effects of bodyweight (10 kg bands) and height (10 cm bands) on […]
May 06, 2016 Annals of Internal Medicine TAKE-HOME MESSAGE The authors of this systematic review evaluated the risk of severe bleeding associated with the use of aspirin for the primary prevention of cardiovascular disease (CVD). The use of low-dose aspirin was associated with a 58% increased risk of major gastrointestinal bleeding and a 27% increased […]
09.14.2015 by Crystal Phend Senior Staff Writer, MedPage Today Low-dose aspirin was recommended for primary prevention of both cardiovascular disease and colorectal cancer for 50- to 59-year-olds by the U.S. Preventive Services Task Force (USPSTF). The draft recommendation applied to only people at 10% or greater 10-year cardiovascular disease risk who aren’t at increased risk […]
Date: August 17, 2015 Research has shown that a regular dose of aspirin reduces the long-term risk of cancer in those who are overweight in an international study of people with a family history of the disease. The study, conducted by researchers at Newcastle University and the University of Leeds, UK, is published in the […]
News · April 21, 2015 PracticeUpdate Editorial Team April 19, 2015—Philadelphia—When taken long-term, regular aspirin use was associated with a modestly reduced overall risk for cancer, which reduction was driven primarily by a lowered risk for colorectal cancers. This result of a prospective study was presented at the American Association of Cancer Research Annual Meeting […]
January 26, 2015 Journal of the American College of Cardiology Volume 65, Issue 2, January 2015 Ravi S. Hira, MD TAKE-HOME MESSAGE Using a US nationwide registry, the authors examined the frequency and practice-level variation of inappropriate aspirin use for preventing cardiovascular disease (CVD). Overall, the frequency of inappropriate aspirin use was 11.6% (N = […]
January 12, 2015 Annals of Oncology TAKE-HOME MESSAGE Investigators in this case-control study in Denmark evaluated the association between daily low-dose aspirin and the risk for developing ovarian cancer. The findings suggest that low-dose aspirin, especially continuous, long-term use, may be associated with a reduced risk for developing epithelial ovarian cancer. Further studies are needed […]
Frontline Medical News, 2014 Nov 17, A Karon Taking nonsteroidal anti-inflammatory drugs for 14 days more than doubled the risk of serious bleeding in patients with atrial fibrillation, and it increased the risk of thromboembolism by 36%, according to a report published online Nov. 17 in Annals of Internal Medicine. Risk of serious bleeding and […]
Susan Jeffrey November 18, 2014 Story Source CHICAGO — A new trial shows no benefit of low-dose, once-daily aspirin in the primary prevention of cardiovascular events in patients with multiple risk factors, including hypertension, diabetes, and dyslipidemia. No benefit was seen for the composite endpoint of nonfatal myocardial infarction (MI), nonfatal stroke, or death from […]
AN EXPERT INTERVIEW WITH CHARLES H. HENNEKENS, MD, DRPH Linda Brookes, MSc, Charles H. Hennekens, MD, DrPH October 29, 2014 OUR ROLLERCOASTER RELATIONSHIP WITH ASPIRIN Opinions on the use of aspirin in the prevention of cardiovascular disease (CVD) have varied over the past 25 years since the Physicians’ Health Study (PHS) first demonstrated conclusively that […]
Medscape Medical News USPSTF: Aspirin Advised When Preeclampsia Risk Is High Jenni Laidman September 09, 2014 Healthy pregnant women at high risk for preeclampsia should take low-dose aspirin daily after 12 weeks of gestation, the US Preventive Services Task Force recommends in new guidelinespublished online September 9 in the Annals of Internal Medicine. This new recommendation takes […]
Steve Stiles August 26, 2014 DALLAS, TX — Daily aspirin can cut the adjusted recurrence risk by more than a third over three to four years after acute therapy for a first “unprovoked” venous thromboembolism(VTE), suggests a combined analysis of two trials comparing aspirin at 100 mg/day vs placebo in patients with recent deep vein thrombosis […]
Benefits Add Up for Regular Aspirin Use Published: Aug 5, 2014 | Updated: Aug 6, 2014 Discussant: Joseph Chao, MD. Average-risk adults in the general population who used aspirin regularly for at least 5 years had a lower risk of cancer, myocardial infarction (MI), stroke, and premature death, according to a comprehensive review of potential […]