Disc

30 Jan
2025
Acupuncture, Disc, Disc Degeneration
By André Broussard, D.C.

Electroacupuncture regulates SIRT1/p53/p21 signaling pathway to prevent stress-induced premature senescence of nucleus pulposus cells in degenerative intervertebral discs

Int Immunopharmacol. 2025 Feb 20:148:114114. doi: 10.1016/j.intimp.2025.114114. Epub 2025 Jan 30. Min Wang PMID: 39889410 DOI: 10.1016/j.intimp.2025.114114 Abstract Stress-induced premature senescence (SIPS) affects cellular functionality due to various stressors. In intervertebral disc degeneration (IVDD), nucleus pulposus (NP) cell dysfunction is crucial. Electroacupuncture (EA) has been used to alleviate low back pain and delay IVDD, but […]

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09 Dec
2024
Chiropractic, Disc, Lumbar Spine & Low Back Pain, Spinal Manipulation/Mobilization
By André Broussard, D.C.

Chiropractic Improves Discogenic Low Back Pain, IVD Structural Integrity and Biochemistry

October 31, 2024 Written by: James Demetrious, DC, DABCO Board Certified Chiropractic Orthopedist The Identification of Chiropractic Biomarkers In their recent paper, Billham et al. offer a case report evaluating intervertebral disc (IVD) structural integrity and degenerative pain biochemistry following a course of Cox flexion-distraction SMT. [1] The authors employed magnetic resonance spectroscopy (MRS) and novel […]

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23 Oct
2024
Acupuncture, Disc Herniation, Lumbar Spine & Low Back Pain, Musculoskeletal System, Sciatica
By André Broussard, D.C.

Acupuncture vs Sham Acupuncture for Chronic Sciatica From Herniated Disk

October 23, 2024 Acupuncture vs Sham Acupuncture for Chronic Sciatica From Herniated Disk TAKE-HOME MESSAGE This randomized clinical trial evaluated the efficacy and safety of acupuncture for the treatment of patients with chronic sciatica pain. The primary outcome was a change in visual analog scale score for leg pain. Participants in the acupuncture group had […]

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11 Oct
2023
Cervical Spine & Neck Pain, Diagnostics, Disc, Disc Degeneration, Headache, MRI
By André Broussard, D.C.

The association between cervical degenerative MRI findings and self-reported neck pain, disability and headache: a cross-sectional exploratory study

Rikke K. Jensen, Kristina B. Dissing, Tue S. Jensen, Stine H. Clausen & Bodil Arnbak Chiropractic & Manual Therapies volume 31, Article number: 45 (2023) Abstract Background Neck pain and headache are highly prevalent conditions and leading causes of disability worldwide. Although MRI is widely used in the management of these conditions, there is uncertainty […]

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22 Mar
2023
Chiropractic, Disc, Disc Herniation, Lumbar Radiculopathy, Spinal Manipulation/Mobilization
By André Broussard, D.C.

Effects of spinal manipulation or mobilization as an adjunct to neurodynamic mobilization for lumbar disc herniation with radiculopathy: a randomized clinical trial

J Man Manip Ther. 2023 Mar 22;1-13. doi: 10.1080/10669817.2023.2192975. Online ahead of print. Musa Sani Danazumi PMID: 36950742 DOI: 10.1080/10669817.2023.2192975 Abstract Objectives: To determine the long-term clinical effects of spinal manipulative therapy (SMT) or mobilization (MOB) as an adjunct to neurodynamic mobilization (NM) in the management of individuals with Lumbar Disc Herniation with Radiculopathy (DHR). Design: Parallel group, single-blind […]

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21 Feb
2023
Chiropractic, Disc, Disc Herniation, Flexion-Distraction, Lumbar HNP, Lumbar Spine & Low Back Pain, Musculoskeletal System, Spinal Manipulation/Mobilization
By André Broussard, D.C.

Magnetic Resonance Spectroscopy Displays the Structural and Biochemical Effects of Spinal Manipulative Therapy in Lumbar Discogenic Pain: a case report

SN Comprehensive Clinical Medicine https://doi.org/10.21203/rs.3.rs-2596102/v1 Jessica F Billham Abstract INTRODUCTION: We report utility of magnetic resonance spectroscopy (MRS) in identifying the intervertebral disc (IVD) as a pain generator, describe the contemporary pathophysiology underlying biochemical and structural components of discogenic low back pain (DLBP), and exhibit therapeutic responses to spinal manipulation. CLINICAL FEATURES: A 29-year old […]

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15 Jan
2023
Cervical Spine & Neck Pain, Cholesterol Issues, Disc Degeneration, Hematologic and Lymphatic, Musculoskeletal System
By André Broussard, D.C.

Association Between Hypercholesterolemia and Neck Pain in a Cross-sectional Population-based Study

Ahorukomeye, Peter BSa,b; Mahajan, Arushi BSb; Du, Jerry Y. MDa; Yu, Charles C. MDc; Bhandutia, Amit K. MDd; Ahn, Nicholas U. MDa,b Spine 48(2):p 137-142, January 15, 2023. | DOI: 10.1097/BRS.0000000000004485 Abstract Study Design. Retrospective cross-sectional analysis. Summary of Background Data. Degenerative changes are a major contributor to chronic neck pain. According to the vascular […]

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01 Nov
2021
Disc, Disc Degeneration, Genetics
By André Broussard, D.C.

A Case–control Study of Major Genetic Predisposition Risk Alleles in Developing DDD in the Northeast US Population: Effects of Gene–gene Interactions

Valtchinov, Vladimir I. PhD SPINE: November 15, 2021 – Volume 46 – Issue 22 – p 1525-1533 Study Design. A case–control study of risk alleles for degenerative disc disease (DDD) using magnetic resonance (MR) imaging for phenotyping. Objective. We aim to provide the first statistically adequately powered study of the relationship between the presence of […]

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08 Oct
2021
Disc, Disc Degeneration, Disc Desiccation, Musculoskeletal System
By André Broussard, D.C.

Lumbar spine intervertebral disc desiccation is associated with medical comorbidities linked to systemic inflammation

Published: 08 October 2021 Lambrechts, M.J., Pitchford, C., Hogan, D. et al. Lumbar spine intervertebral disc desiccation is associated with medical comorbidities linked to systemic inflammation. Arch Orthop Trauma Surg (2021). https://doi.org/10.1007/s00402-021-04194-3 Abstract Introduction Symptomatic disc degeneration is a common cause of low back pain. Recently, the prevalence of low back pain has swiftly risen […]

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09 Sep
2021
Disc, Disc Herniation, Lumbar HNP, Lumbar Spine & Low Back Pain
By André Broussard, D.C.

Retraction of lumbar disc herniation achieved by noninvasive techniques: A case report

World J Clin Cases. 2021 Sep 26;9(27):8082-8089. doi: 10.12998/wjcc.v9.i27.8082. Ping Wang 1, Cai Chen 2, Qing-Hao Zhang 3, Guo-Dong Sun 4, Cong-An Wang 5, Wei Li 6 PMID: 34621865 PMCID: PMC8462224 DOI: 10.12998/wjcc.v9.i27.8082 Abstract Background: Lumbar disc herniation (LDH) has emerged as one of the most common causes of low back pain. The routine treatment approach […]

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07 Aug
2021
Disc, Disc Degeneration, Facet Arthrosis - Lumbar Spine, Musculoskeletal System
By André Broussard, D.C.

Chronology of disc degeneration and facet joint arthritis in lumbar spine is variable – A CT based cross-sectional study

J Orthop Sci. 2021 Aug 17;S0949-2658(21)00235-9. doi: 10.1016/j.jos.2021.07.016. Punit Tiwari PMID: 34412964 DOI: 10.1016/j.jos.2021.07.016 Abstract Background: The notion that disc degeneration (DD) always precedes facet joint arthritis (FJA) has held sway for many decades. However, it is not always the case. We hypothesized that DD is not always the first offender studied the prevalence of […]

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07 May
2021
Disc, Disc Degeneration, Lumbar Spine & Low Back Pain, Musculoskeletal System
By André Broussard, D.C.

Analysis of trends in lumbar disc degeneration using kinematic MRI

Clinical Imaging Volume 79, November 2021, Pages 136-141 Sidney Roberts Highlights • Lumbar disc degeneration increases in severity with age. • Men tend to degenerate at an earlier age than women. • The 5th decade of life is most common for people to develop severe degeneration. Abstract Objective The aim of the current study was […]

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29 Mar
2021
Disc, Disc Degeneration, Lumbar Spine & Low Back Pain, Musculoskeletal System, Physical Modalities, Spinal Decompression, Traction
By André Broussard, D.C.

The effects of axial loading on the morphometric and T2 characteristics of lumbar discs in relation to disc degeneration

Clinical Biomechanics Volume 83, March 2021, 105291 Clinical Biomechanics VahidAbdollah Highlights • Effects of disc compression and traction measured using geometric and T2 centroids. • The largest responses to loading were observed at the lower lumbar levels. • The magnitude of responses to loading were associated with severity of disc degeneration. • T2 disc centroid, […]

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08 Nov
2020
Disc, Disc Herniation, Lumbar Spine & Low Back Pain
By André Broussard, D.C.

Radiological predictors of recurrent lumbar disc herniation: a systematic review and meta-analysis

J Neurosurg Spine. 2020 Nov 27;1-11. doi: 10.3171/2020.6.SPINE20598. Michael Brooks Abstract Objective: Lumbar discectomy for the management of lumbar radiculopathy is a commonly performed procedure with generally excellent patient outcomes. However, recurrent lumbar disc herniation (rLDH) remains one of the most common complications of the procedure, often necessitating repeat surgery. rLDH is known to be […]

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01 Oct
2020
Disc, Disc Degeneration, Musculoskeletal System, Pediatric Low Back Pain, Pediatrics
By André Broussard, D.C.

Disc Degeneration of Young Low Back Pain Patients: A Prospective 30-year Follow-up MRI Study

Sääksjärvi, Simoa,b; Kerttula, Liisa MD, PhDc; Luoma, Katariina MD, PhDa,d; Paajanen, Hannu MD, PhDe; Waris, Eero MD, PhDa,bAuthor Information SPINE: October 1, 2020 – Volume 45 – Issue 19 – p 1341-1347 doi: 10.1097/BRS.0000000000003548 Study Design. A prospective follow-up study. Objective. The aim of this study was to investigate whether early lumbar disc degeneration (DD) […]

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14 Jul
2020
Chronic Low Back Pain, Disc, Disc Degeneration, Lumbar Spine & Low Back Pain, Musculoskeletal System, Radiology
By André Broussard, D.C.

Disc height discrepancy between supine and standing positions as a screening metric for discogenic back pain in patients with disc degeneration

July 14, 2020 Seong Son, MD, Ph.D. The Spine Journal Published:July 17, 2020DOI:https://doi.org/10.1016/j.spinee.2020.07.006 Highlight The diagnosis of discogenic low back pain (LBP) in early to middle stage disc degeneration (Pfirrmann grade II, III, or IV) of the lumbar spine is ambiguous, unless a discography is performed. The disc height (DH) discrepancy ratio between supine and […]

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07 Jul
2020
Chiropractic, Disc, Disc Herniation, Low Back Pain Natural History, Musculoskeletal System, Spinal Manipulation/Mobilization
By André Broussard, D.C.

Regression of Lumbar Disc Herniation Following Non-surgical Treatment – Full Text

European Journal of Molecular & Clinical Medicine, 2020; 7(1): 27-29 Eric Chun-Pu Chu, Divya Midhun Chakkaravarthy, Fa-Sain Lo, Amiya Bhaumik. Abstract Symptomatic disc herniation is the most common disc pathology and can result in substantial disability and poor quality of life. Here, we present a male patient who was diagnosed as having lumbar disc herniation […]

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14 May
2020
Disc, Microbiome
By André Broussard, D.C.

Human intervertebral discs harbour a unique microbiome and dysbiosis determines health and disease

Published: 14 May 2020 Shanmuganathan Rajasekaran European Spine Journal (2020) Abstract Background To document the role of sub-clinical infections in disc disorders and investigate the existence of microbiome in intervertebral discs (IVD). Methods Genomic DNA from 24 lumbar IVDs [8—MRI normal discs (ND) from brain dead yet alive organ donors, 8—disc herniation (DH), 8—disc degeneration […]

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01 Apr
2020
Disc Herniation, Lumbar Spine & Low Back Pain, Lumbar Spine Surgery, Lumbar Stenosis, Musculoskeletal System, Surgery
By André Broussard, D.C.

Patients With Persistent Low Back Pain and Nerve Root Involvement: To Operate, or Not to Operate, That Is the Question

Petersen, Tom PhDa; Juhl, Carsten B. PhDb,c; Fournier, Gilles L. MDdAuthor Information SPINE: April 1, 2020 – Volume 45 – Issue 7 – p 483-490 doi: 10.1097/BRS.0000000000003304 Study Design. Prospective cohort study. Objective. The aims of this study were to evaluate the outcome of surgical and nonsurgical treatment for patients with lumbar herniated disc (LHD) […]

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11 Mar
2020
Disc, Disc Herniation, Lumbar Spine Surgery, Musculoskeletal System, Surgery
By André Broussard, D.C.

Like patching a flat tire: New fix heals herniated discs

MARCH 11, 2020 by Cornell University A new two-step technique to repair herniated discs uses hyaluronic acid gel to re-inflate the disc and collagen gel to seal the hole, essentially repairing ruptured discs like you’d repair a flat tire. After a rupture, a jelly-like material leaks out of a herniated disc, causing inflammation and pain. […]

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