Neurological System

Diverse Role of Biological Plasticity in Low Back Pain and Its Impact on Sensorimotor Control of the Spine

Published: Journal of Orthopaedic & Sports Physical Therapy, 2019 Volume:49 Issue:6 Pages:389–401 DOI: 10.2519/jospt.2019.8716 Synopsis Pain is complex. It is no longer acceptable to consider pain solely as a peripheral phenomenon involving activation of nociceptive neurons. The contemporary understanding of pain involves consideration of different underlying pain mechanisms and an increasing awareness of plasticity in […]

Can the Neck Contribute to Persistent Post-Concussion Symptoms? A Prospective Descriptive Case Series

Published: Journal of Orthopaedic & Sports Physical Therapy, 2019 Volume:0 Issue:0 Pages:1–31 DOI: 10.2519/jospt.2019.8547 Study Design Prospective case series. Background Persistent post-concussion symptoms can arise from a range of sources, including the neck. There is little description of neck assessment findings in people with persistent post-concussion symptoms. Objectives To assess people with persistent symptoms following […]

Spinal manipulation therapy: is it all about the brain? A current review of the neurophysiological effects of manipulation

Journal of Integrative Medicine Available online 9 May 2019 GilesGyer Abstract Spinal manipulation has been an effective intervention for the management of various musculoskeletal disorders. However, the mechanisms underlying the pain modulatory effects of spinal manipulation remain elusive. Although both biomechanical and neurophysiological phenomena have been thought to play a role in the observed clinical […]

Common antibiotic may increase nerve damage and peripheral neuropathy risk

NEUROSCIENCE NEWS MAY 14, 2019 Summary: Fluoroquinolone antibiotics, such as Levofloxacin and Ciprofloxacin, appear to increase the risk of peripheral neuropathy by 47%. However, there is no significant increased risk of developing neuropathy associated with amoxicillin use. Source: University of Dundee Research from the University of Dundee has shown that a commonly used class of […]

IBD Linked to Growing Number of Inflammation-Related Diseases

by Diana Swift  Contributing Writer Expert Critique: Bradley W. Anderson, MD Gastroenterology and Hepatology Fellow Mayo Clinic Rochester, MN Inflammatory bowel disease (IBD), which includes both Crohn’s disease and ulcerative colitis, is unique among gastrointestinal conditions given the breadth of preventative measures needed to promote and maintain patient health and safety. Such measures account for a […]

Spinal Manipulative Therapy Effects in Autonomic Regulation and Exercise Performance in Recreational Healthy Athletes

A Randomized Controlled Trial Valenzuela, Pedro L., MSc∗,†; Pancorbo, Sara, MChiro‡; Lucia, Alejandro, MD, PhD§; Germain, Francisco, MD, PhD∗ Spine: May 1, 2019 – Volume 44 – Issue 9 – p 609-614 doi: 10.1097/BRS.0000000000002908 Study Design. A randomized, double blind, parallel groups, sham-controlled trial. Objective. The aim of this study was to analyze the acute […]

Vitamin D study sheds light on immune system effects

Date: April 17, 2019 Source: University of Edinburgh Summary: Scientists have uncovered fresh insights into how vitamin D affects the immune system and might influence susceptibility to diseases such as multiple sclerosis. Scientists have uncovered fresh insights into how vitamin D affects the immune system and might influence susceptibility to diseases such as multiple sclerosis. […]

Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization

Evid Based Complement Alternat Med. 2019 Mar 7;2019:6173412. doi: 10.1155/2019/6173412. eCollection 2019. Lai HC Abstract Pain can trigger central amplification called central sensitization, which ultimately results in hyperalgesia and/or allodynia. Many reports have showed acupuncture has an analgesic effect. We searched the related article on PubMed database and Cochrane database to discover central sensitization pathway […]

Increased Salience Network Connectivity following Spinal Manipulative Therapy is Associated with Reduced Pain in Chronic Low Back Pain Patients

The Journal of Pain K. Isenburg, M. Loggia April 2019 Volume 20, Issue 4, Supplement, Page S42 Abstract Chronic low back pain (cLBP) has been associated with maladaptive brain plasticity, and non-pharmacological therapies such as Spinal Manipulative Therapy (SMT) have shown promise in reducing pain and modifying intrinsic brain physiology. However, more translational research is […]

Studies Show Amyotrophic Lateral Sclerosis (ALS) May be Caused by Environmental Toxins

By Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. Amyotrophic lateral sclerosis ( ALS) is serious motor neu­ron diseases which falls in the same category as Parkin­son’s disease, multiple sclerosis, etc. It simply means the nerves have been severely damaged and paralysis is expected to result as the disease progresses. Unfortunately, as with most dis­eases, medicine rarely […]

Sugary Beverages Associated With More Severe Multiple Sclerosis Symptoms

Rachel Lutz Publish Date: Friday, March 22, 2019 A new report found that soda and other beverages sweetened with sugar can make symptoms more severe in multiple sclerosis patients. Investigators from St. Josef Hospital Bochum in Germany surveyed multiple sclerosis patients in order to assess the effect of diet on mechanisms implicated in multiple sclerosis […]

Concussions in Sports – Full Text Article

Matthew T. Provencher, MD; Rachel M. Frank, MD; Daniel J. Shubert, MD; Anthony Sanchez, BS; Colin P. Murphy, BA; Ross D. Zafonte, DO Orthopedics. 2019;42(1):12-21https://doi.org/10.3928/01477447-20181231-02 Posted January 21, 2019 Abstract Although concussions are common, they are complex, variable, and not entirely understood in terms of pathophysiology and treatment. The incidence of concussion is expected to […]

Leaky Gut, Leaky Brain: The Role of Zonulin

by Melissa Lee – Fx Medicine 05/13/2016 DOWNLOAD INFOGRAPHIC In recent years an amazing discovery has advanced our understanding of intestinal permeability. In 2000, Dr Alessio Fasano and his team discovered a molecule responsible for modulating intestinal tight junctions (TJs) known as zonulin. To date, zonulin is the only human protein known to reversibly regulate intestinal permeability. Based on Dr Fasano’s […]

Neuroplasticity Altered With Chronic Back Pain

Ingrid Hein October 25, 2018 Patients who suffer chronic lower back pain, particularly those on sick leave, might have different mechanisms of pain control in the brain, results from a study of functional MRI show. Researchers at the American College of Rheumatology 2018 Annual Meeting in Chicago reported a weaker functional MRI signal in emotion-related […]

The Case for Local Needling in Successful Randomized Controlled Trials of Peripheral Neuropathy: A Follow-Up Systematic Review – Full Text Article

Medical Acupuncture Vol. 30, No. 4 Alexandra Dimitrova Published Online:1 Aug 2018 https://doi.org/10.1089/acu.2018.1297 Abstract Objectives: This work follows-up on a systematic review, published in 2017, of acupuncture for the treatment of mono- and polyneuropathy and associated symptoms. Previously reviewed trials of acupuncture for neuropathy primarily used acupuncture points in close proximity to underlying nerves. Further […]

Constellation of Factors Increase Risk of Multiple Sclerosis – Slide Show

by Veronica Hackethal, MD Aug 13, 2018 “How this cocktail of MS genes, organic solvents and smoking contributes so significantly to MS risk warrants investigation,” Gabriele C. DeLuca, MD, DPhil, and Jack Bell, BM, BCh, both of John Radcliffe Hospital (Oxford, UK), wrote in an accompanying editorial.[3] “In the meantime, avoiding cigarette smoke and unnecessary exposure […]

Belly fat linked to cognitive decline

Published Monday 6 August 2018 By Tim Newman Fact checked by Jasmin Collier In the largest study of its type, researchers conclude that having higher levels of belly fat in old age is correlated with a reduction in cognitive function. Dementias, including Alzheimer’s, are a growing concern. As the average age of the population steadily […]

The Role of Magnesium in Neurological Disorders – Full Text Article

Nutrients 2018, 10(6), 730; https://doi.org/10.3390/nu10060730 Anna E. Kirkland Abstract: Magnesium is well known for its diverse actions within the human body. From a neurological standpoint, magnesium plays an essential role in nerve transmission and neuromuscular conduction. It also functions in a protective role against excessive excitation that can lead to neuronal cell death (excitotoxicity), and […]

FDA: New Warnings for Fluoroquinolones (Levaquin, Cipro, etc.)

– Class-wide label changes address mental health side effects, hypoglycemic coma risk by Molly Walker, Staff Writer, MedPage Today July 10, 2018 Manufacturers of fluoroquinolone antibiotics must update their labeling to warn about mental health issues and potential low blood sugar adverse reactions, the FDA said Tuesday. The labeling changes come after what the agency […]

Updated Clinical Guidelines on the Ketogenic Diet in Children with Epilepsy

Jun 20, 2018 Veronica Hackethal, MD The International Ketogenic Diet Study Group has released new clinical guidelines on the ketogenic diet in children with epilepsy. The updated recommendations are the first change since the original guidelines on the subject were published almost 10 years ago. Slide Show at NeurologyTimes