The Lancet, 08/21/2014 Evidence Based Medicine Story Source Bhaskaran K, et al. – High body–mass index (BMI) predisposes to several site–specific cancers, but a large–scale systematic and detailed characterisation of patterns of risk across all common cancers adjusted for potential confounders has not previously been undertaken. Authors aimed to investigate the links between BMI and […]
Abstract Increasing evidence supports the contention that many malignancies, including sporadic colorectal cancer, are driven by the self-renewing, chemotherapy-resistant cancer stem/stem-like cells (CSC/CSLC), underscoring the need for improved preventive and therapeutic strategies targeting CSCs/CSLCs. Omega-3 polyunsaturated fatty acids (ω-3 PUFA), have been reported to inhibit the growth of primary tumors, but their potential as a […]
-Increasing body size had significant associations with 10 common types of cancer, a study involving more than 5 million people showed. by Charles Bankhead, Staff Writer, MedPage Today August 14, 2014 Increasing body size had significant associations with 10 common types of cancer, a study involving more than 5 million people showed. Overall, body mass […]
DNA Test Wins FDA, CMS Approval at Same Time Published: Aug 12, 2014 By Charles Bankhead, Staff Writer, MedPage Today WASHINGTON — The first-ever DNA-based screening test for colorectal cancer has received FDA approval and preliminary approval for Medicare coverage of the test. The Cologuard test detects hemoglobin and mutant DNA in cells sloughed into […]
Gastroenterology. 2014 Aug 12. pii: S0016-5085(14)01001-4. doi: 10.1053/j.gastro.2014.08.005. [Epub ahead of print] Increased Intake of Vegetables, but not Fruit, Reduces Risk for Hepatocellular Carcinoma: A Meta-analysis. Yang Y1, Zhang D2, Feng N3, Chen G4, Liu J5, Chen G6, Zhu Y5. Abstract BACKGROUND: & Aims: The anti-cancer effects of vegetables and fruit have been investigated extensively, […]
Roxanne Nelson August 11, 2014 (Corrected Aug. 12, 2014) The US Food and Drug Administration (FDA) today approved Cologuard (Exact Sciences Corporation), a stool-based colorectal cancer (CRC) in vitro diagnostic device. Cologuard analyzes stool specimens to detect hemoglobin, multiple DNA methylation and mutational markers, and the total amount of human DNA contained in cells that are shed […]
Revamped Prostate Cancer Risk Calculator Now Online Fran Lowry August 08, 2014 The first version of the Prostate Cancer Risk Calculator, developed in 2006 to help men and their doctors assess their risk for prostate cancer, has been completely revamped. Version 2.0 uses current risk factors and gives a more nuanced result to help a man and his […]
Benefits Add Up for Regular Aspirin Use Published: Aug 5, 2014 | Updated: Aug 6, 2014 Discussant: Joseph Chao, MD. Average-risk adults in the general population who used aspirin regularly for at least 5 years had a lower risk of cancer, myocardial infarction (MI), stroke, and premature death, according to a comprehensive review of potential […]
Eur J Cancer Prev. 2014 Sep;23(5):481-90. doi: 10.1097/CEJ.0000000000000015. Sweetened carbonated beverage consumption and cancer risk: meta-analysis and review. Boyle P1, Koechlin A, Autier P. Abstract There is speculation on an association between sweetened, carbonated beverage consumption and cancer risk. This study aimed to examine this issue. Over 50 independent estimates of risk were available, 11 […]
Annals of Oncology, 08/04/2014 Clinical Article Suh B, et al. – This study suggest that low AGR is a risk factor for cancer incidence and mortality, both short–term and long–term, in a generally healthy screened population. The results of this study need to be replicated in larger studies, along with the determination of the sensitivity […]
Surgeon General: Tanning, indoor Tanning Must Stop Frontline Medical News, 2014 Jul 29, A Ault The U.S. Surgeon General’s office is calling on Americans to do more to help prevent skin cancer, saying that it is a growing public health problem. The five-point call to action singled out ultraviolet light exposure – from indoor and […]
PracticeUpdate Editorial Team July 28, 2014, New York–Results of a systematic review of literature from 1966 of the natural history of papillary thyroid microcarcinoma (PTMC) revealed that the condition is being over-diagnosed and over-treated. The review was presented Sunday at the Fifth World Congress of the International Federation of Head and Neck Oncologic Societies (IFHNOS) […]
Exposure to the sun could actually HALVE your chance of developing some forms of cancer Sun exposure could potentially reduce the risks of ovarian, oesophageal and pancreatic cancers Not enough UV rays may cause children to develop rickets and ostemomalacia in adults Professor Neale is currently recruiting 25,000 Australians over 60 to participate in a […]
Story Source BY JOHN UPTON • July 22, 2014 • 10:51 AM Reduced carb intake among mice protected them from colon cancer. • Colorectal cancer is a scourge of modern times, killing 50,000 Americans every year. It’s responsible for a heavier death toll than any other cancer besides lung cancer and, when it comes to women, breast cancer. And […]
Date: July 17, 2014 Source: Cell Press Summary: Colorectal cancer has been linked to carbohydrate-rich western diets, but the underlying mechanisms have been unclear. A new study shows that gut microbes metabolize carbohydrates in the diet, causing intestinal cells to proliferate and form tumors in mice that are genetically predisposed to colorectal cancer. Treatment with […]
Association between class III obesity (BMI of 40-59 kg/m2) and mortality: a pooled analysis of 20 prospective studies Full Text PLoS Medicine, 07/14/2014 Evidence Based Medicine Clinical Article Kitahara CM, et al. – The prevalence of class III obesity (body mass index [BMI]>=40 kg/m2) has increased dramatically in several countries and currently affects 6% of […]
PracticeUpdate July 10, 2014 Louis Barich MD The FDA has reclassified tanning beds after recognizing the dangers of ultraviolet (UV) tanning radiation and now requires warnings on sunlamp products. These are the early steps to continued regulatory efforts that should eventually result in a total ban on UV tanning radiation for minors. All of us […]
MedPageToday.com Published: Jul 9, 2014 By Charles Bankhead, Staff Writer, MedPage Today Action Points Vasectomy was associated with an increased risk of prostate cancer overall and risk was elevated for high-grade and lethal disease. Point out however that the absolute increase in risk was relatively modest. Men who had a vasectomy had a significantly greater […]
PracticeUpdate.com RESEARCH · July 07, 2014 TAKE-HOME MESSAGE Analysis of 40,405 men from the Health Professionals Follow-Up Study found an increased risk for overall (HR, 1.10) and lethal (HR, 1.19) prostate cancer in men who underwent vasectomy, despite controlling for confounding factors. The overall risk for death from prostate cancer in the entire population was […]
Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. Story Source Wouldn’t it be great if medical science discovered a way to detect breast cancer much sooner and more accurately and best of all without having to have your breast painfully compressed via a mammogram? Early breast cancer detection can significantly improve survival rates. However, current diagnostic tests […]