Matrix Metalloproteinase

Therapeutic potential of Panax ginseng and ginsenosides in the treatment of chronic obstructive pulmonary disease

Complementary Therpies in Medicine Published Online: August 20, 2014 DOI:http://dx.doi.org/10.1016/j.ctim.2014.08.006 Highlights The authors reviewed Panax ginsengand ginsenosides for their potential to treat COPD. Experimental cell and animal studies were evaluated. Panax ginseng and ginsenosides have anti-inflammatory and anti-oxidative effects. Panax ginseng and ginsenosides may be suitable therapeutic targets for the treatment of COPD. Summary Background Chronic obstructive pulmonary […]

Matrix Metalloproteinase-9 Test for Confirming Dry Eye Disease

June 24, 2014 TAKE-HOME MESSAGE This prospective, sequential, masked clinical trial enrolled 237 patients to compare the InflammaDry test with clinical assessment (tear break-up time [TBUT], Schirmer tear testing, and corneal staining) for the confirmation of dry eye. InflammaDry had a total positive agreement of 81% (127/157) and negative agreement of 98% (78/80). The authors […]

Sugar-Sweetened Beverage Consumption Is Associated with Abdominal Fat Partitioning in Healthy Adults

Ma J, et al. – In this cross–sectional analysis, the authors examined whether habitual sugar–sweetened beverage (SSB) consumption and diet soda intakes are differentially associated with deposition of body fat. Daily consumers of SSBs had a 10% higher absolute visceral adipose tissue (VAT) volume and a 15% greater VAT–to–SAT ratio compared with nonconsumers, whereas consumption […]

Extra Virgin Olive Oil Phenols Suppress Migration and Invasion of Bladder Cancer Cells Through Modulation of Matrix Metalloproteinase

Coccia A, et al. – This study aimed to investigate the potential antimetastatic effect of total phenols extracted from EVOO against the human transitional bladder carcinoma cell line T24. The results may support the epidemiological evidences that link olive oil consumption to health benefits and may represent a starting point for the development of new […]

Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain

Global Spine J 2013; 03(03): 175-184 Karin Wuertz Abstract Although degeneration of the intervertebral disk has historically been described as a misbalance between anabolic and catabolic factors, the role of inflammatory mediators has long been neglected. However, past research clearly indicates that inflammatory mediators such as interleukin (IL)-1β, IL-6, IL-8 and tumor necrosis factor-α are […]