NF-kB

Pulsed Electromagnetic Fields Reduce Interleukin-6 Expression in Intervertebral Disc Cells Via Nuclear Factor-κβ and Mitogen-Activated Protein Kinase p38 Pathways

Spine: November 15, 2019 – Volume 44 – Issue 22 – p E1290-E1297 doi: 10.1097/BRS.0000000000003136 Tang, Xinyan PhD Study Design. This is an in vitro study of bovine disc cells exposed to pulsed electromagnetic fields. Objective. The purpose of the present study was to investigate whether pulsed electromagnetic fields (PEMF) effects on the expression of […]

The Pathogenesis of Diabetes Mellitus by Oxidative Stress and Inflammation: Its Inhibition by Berberine – Full Text Article

Front. Pharmacol., 27 July 2018 | https://doi.org/10.3389/fphar.2018.00782 Xueling Ma A substantial knowledge on the pathogenesis of diabetes mellitus (DM) by oxidative stress and inflammation is available. Berberine is a biologically active botanical that can combat oxidative stress and inflammation and thus ameliorate DM, especially type 2 DM. This article describes the potential of berberine against […]

Meditation and yoga can ‘reverse’ DNA reactions which cause stress, new study suggests

Date: June 15, 2017 Source: Coventry University Summary: Mind-body interventions (MBIs) such as meditation, yoga and Tai Chi don’t simply relax us; they can ‘reverse’ the molecular reactions in our DNA which cause ill-health and depression, according to a study. Mind-body interventions (MBIs) such as meditation, yoga and Tai Chi don’t simply relax us; they […]

Efficacy and Safety of White Willow Bark

Phytother Res. 2015 May 22. doi: 10.1002/ptr.5377. [Epub ahead of print] Efficacy and Safety of White Willow Bark (Salix alba) Extracts. Shara M, Stohs SJ. Abstract Willow bark extract has been used for thousands of years as an anti-inflammatory, antipyretic, and analgesic. In spite of its long history of use, relatively few human and animal […]

NF-κB signaling pathway is a key mediator of disc degeneration

Effects of Nuclear Factor Kappa B Signaling Pathway in Human Intervertebral Disc Degeneration Zhongyi, Sun PhD; Sai, Zhao PhD; Chao, Liu PhD; Jiwei, Tian PhD Spine 15 February 2015 Vol. 40 – Issue 4: p 224–232 Abstract Study Design. IL-1β (interleukin-1β) can activate human nucleus pulposus cells with or without nuclear factor kappa B (NF-κB) […]

Oil palm phenolics inhibit pancreatic cancer cell proliferation via suppression of NF-κB pathway

Anticancer Research, 01/15/2015 Clinical Article Ji X, et al. – Oil palm phenolics (OPP) or Palm Juice (PJ), a water soluble extract from the palm fruit (Elaies guineensis) has been documented to have anti–carcinogenic activities in various cancer types. The results demonstrate the anti–tumor effects of OPP on PaCa cells, providing initial evidence towards its […]

Peyronie’s Disease and Vitamin E – Interview with Gianni Paulis, M.D.

Gianni Paulis, MD Service of Andrology, Regina Apostolorum Hospital Via San Francesco, 50 – CAP 00041 Albano Laziale, Rome, Italy +39 06932989 / +39 069321138 (FAX) paulisg@libero.it “Efficacy of Vitamin E in the Conservative Treatment of Peyronie’s Disease: Legend or Reality? A Controlled Study of 70 Cases,” Andrology. 2013 Jan;1(1):120-8. 50257 (11/2013) Kirk Hamilton: Can you […]

Diet and cancer: risk factors and epidemiological evidence

Maturitas. 2014 Mar;77(3):202-8. doi: 10.1016/j.maturitas.2013.11.010. Epub 2013 Dec 11. Baena Ruiz R, Salinas Hernández P. Abstract BACKGROUND: Diet represents 30-35% of risk factors that contribute to the onset of cancer. Some foods and dietary patterns have been linked to the risk of various cancers. However epidemiological available data are not consistent for many foods and […]

Curcumin for osteoarthritis management – Full Text Article

Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management Yves Henrotin Springerplus. 2013; 2: 56. Published online Feb 18, 2013. doi: 10.1186/2193-1801-2-56 Full Text Article Abstract The management of osteoarthritis represents a real challenge. This complex and multi-factorial disease evolves over decades and requires not only the alleviation […]