Fracture Risk Factor

Leg-Stand Test Predicts Hip-Fracture Risk in Women

Nancy A. Melville September 13, 2014 HOUSTON — The inability to stand on 1 leg for 10 seconds or to squat down to reach the floor represent strong early predictors of hip fracture and mortality in postmenopausal women, according to a 15-year follow-up study presented here at the American Society for Bone and Mineral Research […]

Subtrochanteric femoral fracture – bisphosphonate related

Case contributed by: Dr Patsy Robertson Story Source Presentation: 78 year old female, thigh pain following a fall from a car Patient Data: Age: 78 Gender: Female Displaced subtrochanteric fracture of the left femur. The left hip is enlocated. Note is made of the widening of the lateral cortex proximal and distal to the fracture. […]

Dietary acid load, kidney function, osteoporosis, and risk of fractures in elderly men and women

Published: 16 September 2014 T. Jia, L. Byberg Osteoporosis International volume 26, pages563–570(2015) Abstract Summary Because kidney dysfunction reduces the ability to excrete dietary acid excess, we hypothesized that underlying kidney function may have confounded the mixed studies linking dietary acid load with the risk of osteoporosis and fractures in the community. In a relatively […]

Sulfonylureas and TZDs May Up Fracture Risk in Diabetes

Medscape Medical News > Conference News Miriam E. Tucker June 15, 2014 SAN FRANCISCO — The oral diabetes drug classes of thiazolidinediones (TZDs/Brand Names) and sulfonylureas (Brand Names) both boost the risk for fractures compared with metformin, a large database analysis has found. The observational study confirms previous findings of increased fracture risk with TZDs but is the first […]

Citing Fracture Risk, Watchdog Group Sues FDA to Force GERD Drug Warning

Published: Apr 30, 2014 By Elbert Chu The FDA failed to respond to a 2011 petition demanding strong warnings about proton pump inhibitors (PPIs), according to a Public Citizen’s lawsuit filed today. Public Citizen’s lawsuit seeks a ruling from the U.S. District Court of the District of Columbia that the FDA unlawfully withheld action, and calls for an […]

Uric Acid Linked to Fracture Risk

 — Older men with higher uric acid levels may be at increased risk for hip fracture, researchers reported here. by Kristina Fiore, Staff Writer, MedPage Today April 28, 2014 AS VEGAS — Older men with higher uric acid levels may be at increased risk for hip fracture, researchers reported here. In a prospective cohort study, […]

More Fractures Seen When Vitamin D Is Consistently Low

Norra MacReady April 15, 2014 Prolonged low levels of vitamin D increase long-term fracture risk in elderly women, a new study confirms. Low serum vitamin D levels at baseline and at a 5-year follow-up examination were associated with a significantly increased incidence of hip fractures at a 10-year follow-up examination, lead author David Buchebner, PhD, […]

Magnesium intake, bone mineral density, and fractures

Results from the Women’s Health Initiative Observational Study American Journal of Clinical Nutrition, 02/10/2014  Review Article Orchard TS, et al. – The authors examined magnesium intake as a risk factor for osteoporotic fractures and altered bone mineral density (BMD). Lower magnesium intake is associated with lower BMD of the hip and whole body, but this […]

Scores on the Safe Functional Motion Test Are Associated with Prevalent Fractures and Fall History

Chris P. Recknor, MD Physiother Can. 2013 Winter; 65(1): 75–83. Published online 2013 January 28. doi: 10.3138/ptc.2011-25BH PubMed Full Text Reference ABSTRACT Purpose: The Safe Functional Motion test (SFM) was developed to measure observed body mechanics and functional motion associated with spine load, balance, strength, and flexibility during everyday tasks to profile modifiable risks for osteoporotic […]

Children with mild trauma fractures have lower bone strength

January 8, 2014 Full Story Children with forearm fractures that occurred due to mild trauma have lower bone strength compared to other children, predisposing them to osteoporotic fractures later in life, according to a recently published study. “Our study highlights the need for clinicians to consider the level of trauma preceding the injury, when treating […]

Hip Fractures Increase With Chronic Intestinal Damage in Celiac Disease

Fran Lowry January 17, 2014 Full Story (may require free registration): http://www.medscape.com/viewarticle/819382 Chronic damage in the small intestine is a risk factor for hip fracture in patients with celiac disease (CD), according to a cohort study published online January 16 in the Journal of Clinical Endocrinology & Metabolism. “[CD] is associated with an increased fracture risk, […]

Milk Consumption in Teens Does Not Reduce Hip Fracture Risk

Steven Fox November 19, 2013 Milk consumption during adolescence is not associated with decreased risk for hip fracture later in life, according to results from a new study. In fact, high consumption of milk may actually up risk by increasing height. The study was published online November 18 in JAMA Pediatrics. “Greater milk consumption during childhood and adolescence contributes to […]

Glycation Product Linked to Hip Fracture Risk

Published: Nov 1, 2013 | Updated: Nov 1, 2013 By Cole Petrochko, Staff Writer, MedPage Today Full Story:  http://www.medpagetoday.com/Geriatrics/GeneralGeriatrics/42648 Action Points A characteristic of biological aging is the non-enzymatic glycation of long-lasting proteins, such as collagen, which weakens collagen’s biomechanical properties and leads to increased bone matrix stiffening and fragility. This study shows that increasing […]

More Medication Increases Hip Fracture Risk

The Study: Polypharmacy correlates with increased risk for hip fracture in the elderly: a population-based study. The Facts: a. Hip fracture is an important public health issue. b. The authors looked at the insurance claims of 2328 elderly patients in Taiwan who had previously suffered a hip fracture. c. They sought to see if hip […]

Calcium Supplements and Fracture Prevention

Douglas C. Bauer, M.D. N Engl J Med 2013; 369:1537-1543October 17, 2013DOI: 10.1056/NEJMcp1210380 This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author’s clinical recommendations. A 62-year-old healthy woman presents for […]

Spine Injections May Set Stage for Fractures

Published: Jun 7, 2013 | Updated: Jun 10, 2013 By Elizabeth DeVita Raeburn , Contributing Writer, MedPage Today Download Complementary Copy of Article Action Points Lumbar epidural steroid injections are often prescribed for the treatment of radiculopathy or neurogenic claudication arising from compression of spinal nerves. In this retrospective cohort study, an increasing number of […]

Vitamin D Status Predicts Hip Fracture Risk

Published: May 17, 2013 | Updated: May 18, 2013 By Kristina Fiore , Staff Writer, MedPage Today Action Points In this prospective case-cohort study of hip fractures, there was an increased risk of hip fracture in subjects in the lowest compared to the highest quartile of serum 25-hydroxyvitamin D level. The association was stronger in […]

Central Fat Has Role in Women’s Fracture Risk

Published: Apr 12, 2013 By Nancy Walsh , Staff Writer, MedPage Today Action Points Older women with low abdominal fat stores were at substantially higher risk for fractures, particularly of the vertebrae. Note that fracture risk among both women and men was significantly greater with older age, previous fracture, history of falls, and lower bone […]

Effect of epidural steroid injection on bone mineral density and markers of bone turnover in postmenopausal women

Al-Shoha A, et al. Spine (Phila Pa 1976). 2012 Dec 1;37(25):E1567-71. doi: 10.1097/BRS.0b013e318270280e. Abstract STUDY DESIGN: A prospective, observational study. OBJECTIVE: To evaluate the effect of epidural steroid injection (ESI) on bone mineral density (BMD) in postmenopausal women. SUMMARY OF BACKGROUND DATA: ESIs are used to treat the pain associated with radiculopathy. Although it is […]

Flattening of sagittal spinal curvature as a predictor of vertebral fracture

Osteoporos Int. 2008 Jan;19(1):65-9. Epub 2007 Sep 14. Flattening of sagittal spinal curvature as a predictor of vertebral fracture. Kobayashi T Abstract In a 12-year prospective study of 100 adult volunteers, incident vertebral fractures were analyzed for potential predictors. Decreased sagittal spinal curvature and pre-existing fractures were identified as independent predictors. The risk of vertebral […]