Vitamin D

The Role of Vitamin Supplementation in the Prevention of Cardiovascular Disease Events

Desai CK1, Huang J, Lokhandwala A, Fernandez A, Riaz IB, Alpert JS. Clin Cardiol. 2014 May 23. doi: 10.1002/clc.22299. [Epub ahead of print] Abstract The production, sale, and consumption of multiple vitamins is a multibillion-dollar industry. Most Americans take some form of supplement ostensibly for prevention of cardiovascular disease. It has been claimed that vitamin […]

Carpal Tunnel Syndrome – Nutritional Considerations

MAY 30, 2013 BY CHIROTRUST Carpal Tunnel Syndrome (CTS) is a condition where the median nerve that arises in the neck and travels through the shoulder, arm, and into the hand becomes compressed. Compression of the median nerve results in tingling, numbness, pain and/or weakness that affects the 2nd, 3rd, and thumb-side half of the 4th fingers. It […]

Ulcerative Colitis Activity and Vitamin D Deficiency

Faten N. Aberra, MD, MSCE Assistant Professor of Medicine Division of Gastroenterology Perelman School of Medicine at the University of Pennsylvania Hospital of the University of Pennsylvania Penn Tower – 9th Floor, 1 Convention Ave Philadelphia, PA 19104 215-615-4951/ 215-662-6530 (FAX) Faten.aberra@uphs.upenn.edu “Vitamin D Deficiency is Associated with Ulcerative Colitis Disease Activity,” Dig Dis Sci, […]

Low Vitamin C Linked to Intracerebral Hemorrhage

Pauline Anderson May 01, 2014 PHILADELPHIA — A new study finds a link between vitamin C depletion and increased risk for intracerebral hemorrhage (ICH). In a case–control study, researchers found vitamin C depletion was more common among ICH cases than matched controls. “This original study suggests that a low plasma vitamin C concentration is a […]

Vitamin D: A Predictor of Prostate Cancer

Published: May 2, 2014 | Updated: May 5, 2014 By Charles Bankhead, Staff Writer, MedPage Today Action Points In African-American men, vitamin D deficiency was associated with increased odds of prostate cancer diagnosis on biopsy. In both European-American and African-American men, severe vitamin D deficiency was positively associated with higher Gleason grade and tumor stage. […]

Avoidance of sun exposure is a risk factor for all-cause mortality

Results from the MISS cohort Journal of Internal Medicine, 04/22/2014  Evidence Based Medicine Clinical Article Lindqvist PG, et al. – The results of this study provide observational evidence that avoiding sun exposure is a risk factor for all–cause mortality. Following sun exposure advice that is very restrictive in countries with low solar intensity might in […]

Vitamin D Blog: Muscle Pain in the ED

Published: Apr 21, 2014 By Kristina Fiore, Staff Writer, MedPage Today Patients presenting to the emergency department with widespread muscle pain may have very low levels of vitamin D, warns a case report in the Journal of Emergency Medicine. A 22-year-old African-American woman complained of diffuse myalgia — with pain in the chest, back, and legs — […]

Plasma vitamin D and prostate cancer risk

Results from the selenium and vitamin E cancer prevention trial Cancer Epidemiology, Biomarkers & Prevention, 04/18/2014  Clinical Article Kristal AR, et al. – The results of this study suggests that both low and high vitamin D concentrations were associated with increased risk of prostate cancer, and more strongly for high–grade disease. Methods Data for this case (n=1,731)–cohort […]

Vitamin D Blog: D’s Role in Weight Loss

by Kristina Fiore Staff Writer, MedPage Today March 17, 2014 Simply supplementing vitamin D as part of a dietary intervention won’t necessarily aid weight loss, unless patients actually achieve levels of 25 (OH)D of 32 ng/mL or more. Those are the findings from a year-long randomized controlled trial in 218 overweight and obese women with […]

More Fractures Seen When Vitamin D Is Consistently Low

Norra MacReady April 15, 2014 Prolonged low levels of vitamin D increase long-term fracture risk in elderly women, a new study confirms. Low serum vitamin D levels at baseline and at a 5-year follow-up examination were associated with a significantly increased incidence of hip fractures at a 10-year follow-up examination, lead author David Buchebner, PhD, […]

Vitamin D and central hypersensitivity in patients with chronic pain

Pain Med. 2014 Sep;15(9):1609-18. doi: 10.1111/pme.12454. Epub 2014 Apr 14. von Känel R1, Müller-Hartmannsgruber V, Kokinogenis G, Egloff N. Abstract BACKGROUND: Low vitamin D is implicated in various chronic pain conditions with, however, inconclusive findings. Vitamin D might play an important role in mechanisms being involved in central processing of evoked pain stimuli but less so for spontaneous clinical […]

Vitamin D and risk of cause specific death

Systematic review and meta-analysis of observational cohort and randomised intervention studies Chowdhury R, et al. Show all BMJ. 2014 Apr 1;348:g1903. doi: 10.1136/bmj.g1903. Comment in BMJ. 2014;348:g2280. Abstract OBJECTIVE: To evaluate the extent to which circulating biomarker and supplements of vitamin D are associated with mortality from cardiovascular, cancer, or other conditions, under various circumstances. DESIGN: Systematic review and […]

Vitamin D and Depression

Reference: “Vitamin D and Depression: A Systematic Review and Meta-Analysis Comparing Studies with and without Biological Flaws,” Spedding S, Nutrients, 2014 April 11; 6(4): 1501-18. (Address: Nutritional Physiology Research Centre, University of South Australia, City East Campus, North Tce, Adelaide, SA 5000, Australia. E-mail: spedding@adam.com.a ). Summary: In a systematic review and meta-analysis of studies […]

Vitamin D May Pare BP for Blacks

Published: Apr 11, 2013 By Crystal Phend , Senior Staff Writer, MedPage Today Story Source Action Points Blacks have higher rates of hypertension than whites in the U.S. and also have lower circulating levels of 25(OH)D. In this study, 3 months of vitamin D supplementation had a small to modest effect to lower systolic blood […]

Doubt Over Role of Vitamin D, Even to Limit Fractures

Becky McCall April 03, 2014 Full Story New results from extensive analyses of observational and randomized clinical trials (RCTs) suggest that vitamin D given alone does not appear to increase bone-mineral density or reduce the risk for fractures or falls in older people, contrary to many previous reports. The research also signifies that a clear […]

Vitamin D Not Linked With Heart Risk in Men

Published: Apr 1, 2014 | Updated: Apr 2, 2014 By Nancy Walsh, Senior Staff Writer, MedPage Today Full Story Action Points Note that this large observational cohort study failed to demonstrate a significant association between low vitamin D levels and cardiovascular outcomes. The modest association between low Vitamin D levels and cerebrovascular disease will need […]

Cigarette smoking, vitamin D3 deficiencies in patients with chronic rhinosinusitis

Cigarette smoke exposure is associated with vitamin D3 deficiencies in patients with chronic rhinosinusitis J Allergy Clin Immunol. 2014 Mar 31. pii: S0091-6749(14)00207-3. doi: 10.1016/j.jaci.2014.01.039. [Epub ahead of print] Mulligan JK PubMed Reference Journal Reference Abstract BACKGROUND: Cigarette smoke (CS) plays a role in the exacerbation of chronic rhinosinusitis (CRS); however, the mechanism for this […]

Associations between serum 25-hydroxyvitamin d concentrations and multiple health conditions, physical performance measures, disability, and all-cause mortality

The Concord Health and Ageing in Men Project Hirani V J Am Geriatr Soc. 2014 Mar;62(3):417-25. doi: 10.1111/jgs.12693. Epub 2014 Feb 27. The study aims to explore associations between serum 25–hydroxyvitamin D (25(OH)D) levels and a wide range of health conditions, physical performance measures, disability, and mortality in a large epidemiological study to identify an […]

Vitamin D Linked to Enhanced Breast Cancer Survival

Fran Lowry March 13, 2014 Women with high levels of vitamin D in their blood when they are diagnosed with breast cancer are almost twice as likely to survive as those with low levels of vitamin D, according to a meta-analysis published in the March issue of Anticancer Research. The meta-analysis looked at 5 studies of serum 25-hydroxyvitamin D (25[OH]D) […]

Calcium, Vitamin D Benefit Older Women’s Lipid Profiles

Published: Mar 10, 2014 By Charles Bankhead, Staff Writer, MedPage Today Full Story   Action Points In this randomized trial in postmenopausal women, supplemental CaD significantly increased 25[OH]D3 concentrations and decreased LDL -C. Higher concentrations of 25[OH]D3 were also associated with modestly higher HDL-C levels and lower triglyceride levels.   Postmenopausal women had significant improvement […]