Obesity

Exploration of the Inter-Relationships Between Obesity, Physical Inactivity, Inflammation, and Low Back Pain

Hashem, Lukas E., BSc Spine: September 1, 2018 – Volume 43 – Issue 17 – p 1218-1224 doi: 10.1097/BRS.0000000000002582 Study Design. Retrospective analysis wherein 103 patients were considered, and 76 patients were included: 49 were classified as chronic non-specific low back pain (CNSLBP) (Study group) and 27 had identifiable cases of specific chronic low back pain (LBP) (Control […]

Belly fat linked to cognitive decline

Published Monday 6 August 2018 By Tim Newman Fact checked by Jasmin Collier In the largest study of its type, researchers conclude that having higher levels of belly fat in old age is correlated with a reduction in cognitive function. Dementias, including Alzheimer’s, are a growing concern. As the average age of the population steadily […]

Obesity Surgery Tames Knee OA Pain

Most pain reduction in those with greatest weight loss by Nancy Walsh, Senior Staff Writer, MedPage Today March 23, 2018 Laparoscopic gastric band (LAGB) surgery was associated with significant decreases in knee pain from osteoarthritis (OA), with the greatest improvements seen among those whose body mass index (BMI) had the greatest decreases and among younger […]

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8. Thaiss CA. Abstract Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse models of obesity and diabetes that hyperglycemia drives intestinal barrier permeability, through GLUT2-dependent transcriptional reprogramming of intestinal […]

The Association Among Overweight, Obesity, and Low Back Pain in U.S. Adults: A Cross-Sectional Study of the 2015 National Health Interview Survey

Trent Peng, MS, DC Abstract Objective The purpose of this study was to explore the association between obesity (via body mass index [BMI]) and presence of low back pain (LBP) in a representative sample of US adults, aged ≥18 years. Methods This cross-sectional study used data from 32 060 respondents to the 2015 National Health […]

Childhood Antibiotics and Adult Health – Video

Antibiotics play an important role in medicine, but as you may already know, the CDC states that they are frequently overused: up to 50% of antibiotic prescriptions are not optimal or effective.1 Systemic effects are particularly dramatic when antibiotics are given to infants, and research suggests that the effects of antibiotics on the pediatric microbiome […]

How fruit juice affects the gut

FEBRUARY 07, 2018 Healthline/Medical News Today It was previously believed that fructose, which is the sugar found in fruit and fruit juice, is processed by the liver. However, a new study suggests that fructose is mainly processed in the small intestine. The study, which is published in the journal Cell Metabolism, reveals that processed high-sugar food and […]

Ketogenic diet in endocrine disorders: Current perspectives

J Postgrad Med. 2017 Oct-Dec;63(4):242-251. doi: 10.4103/jpgm.JPGM_16_17. Gupta L, Khandelwal D, Kalra S, Gupta P, Dutta D5, Aggarwal S. Abstract Ketogenic diet (KD) is a high-fat, adequate-protein, and low-carbohydrate diet that leads to nutritional ketosis, long known for antiepileptic effects and has been used therapeutically to treat refractory epilepsy. This review attempts to summarize the […]

Artificial Sweeteners No Boon for BMI

Didn’t show effects in RCTs; tied to BMI boost in cohort studies July 17, 2017 by Scott Harris, Contributing Writer, MedPage Today Artificial sweeteners don’t appear to have any significant effects on body mass index (BMI), according to a review and meta-analysis. In randomized controlled trials, these sweeteners had no effects on BMI, and in […]

Effect of Moderate-Intensity Exercise on Inflammatory Markers Among Postmenopausal Women

J Phys Act Health. 2017 Jun;14(6):479-485. doi: 10.1123/jpah.2016-0319. Epub 2017 Mar 2. Chagas EFB, Bonfim MR, Turi BC, Brondino NCM, Monteiro HL. Abstract BACKGROUND: Declines in ovarian function in postmenopausal women may contribute to increase inflammatory cytokines, which can lead to chronic diseases. However, studies have shown that exercise interventions are important to manage inflammatory conditions. Thus, the objective of […]

Association Between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes

May 15, 2017 Journal of Investigative Dermatology TAKE-HOME MESSAGE This retrospective analysis of 1804 melanoma patients from 1998 to 2008 investigated the effect of body mass index (BMI) and C-reactive protein levels on melanoma outcomes. Increased BMI was associated with lower overall and melanoma-specific survival. Increased BMI was also associated with lower overall and melanoma-specific […]

Sugar and artificially sweetened beverages linked to obesity: A systematic review and meta-analysis

APRIL 18, 2017 QJM: An International Journal of Medicine Ruanpeng D, et al. Researchers evaluate the relationship between intake of sugar and artificially sweetened soda and obesity. This study exhibited an important relationship amongst sugar and artificially sweetened soda intake and obesity. This finding brings issues to light and question of the negative clinical effect […]

Obesity mediates the association between Mediterranean diet consumption and insulin resistance and inflammation in US adults

The Journal of Nutrition, 03/20/2017Park YM, et al. This study was performed to explore whether the relationship between Med–diet intake and markers of insulin resistance and inflammation are mediated by body mass index (BMI) or waist circumference (WC) in a representative US population. These outcomes propose that decreasing abdominal obesity may play an imperative role […]

Mediterranean diet may decrease pain associated with obesity

Published: Friday 24 February 2017 Eating a Mediterranean diet could decrease the chances an overweight person will experience regular pain, new research suggests. A well-established connection between body weight and chronic pain might be explained by inflammation in the body, and the study points to anti-inflammatory foods including fish, nuts and beans as a key […]

Dietary Intake Mediates the Relationship of Body Fat to Pain

January 26, 2017 Pain TAKE-HOME MESSAGE A 3-hour home visit was conducted with 98 healthy adults in the community to collect information on environment, food-related behaviors, and adiposity to evaluate the effect of dietary intake of anti-inflammatory foods on the relationship of body fat to body pain. Modelling revealed that quality of dietary intake mediated […]

Obesity does not increase the risk of chronic low back pain when genetics are considered. A prospective study of Spanish adult twins

The Spine Journal Volume 17, Issue 2, February 2017, Pages 282–290 Amabile Borges Dario, MSc Abstract Background Context Obesity is commonly investigated as a potential risk factor for low back pain (LBP); however, current evidence remains unclear. Limitations in previous studies may explain the inconsistent results in the field, such as the use of a […]

Morbid Obesity and Lumbar Fusion in Patients Older Than 65 Years: Complications, Readmissions, Costs, and Length of Stay

Spine: 15 January 2017 – Volume 42 – Issue 2 – p 122–127 doi: 10.1097/BRS.0000000000001692 Epidemiology Puvanesarajah, Varun MD; Werner, Brian C. MD; Cancienne, Jourdan M. MD; Jain, Amit MD; Pehlivan, Hakan MD; Shimer, Adam L. MD; Singla, Anuj MD; Shen, Francis MD; Hassanzadeh, Hamid MD Study Design. Retrospective database review. Objective. The aim of […]

The effect of obesity on treatment outcomes for low back pain

Stanley C. Ewald Chiropractic & Manual Therapies 2016 24:48 DOI: 10.1186/s12998-016-0129-4 ©  The Author(s). 2016 Received: 25 January 2016 Accepted: 20 October 2016 Published: 12 December 2016 Abstract Background The objective of this study was to estimate the effect of obesity, as measured by body mass index (BMI), on treatment outcomes for low back pain (LBP). Methods Data from the University of California, Los Angeles, and […]

Modifiable risk factors for chronic back pain: insights using the co-twin control design

The Spine Journal Volume 17, Issue 1, January 2017, Pages 4–14 Pradeep Suri, MD, MS Abstract Background Inconsistent associations between modifiable risk factors and chronic back pain (CBP) may be due to the inability of traditional epidemiologic study designs to properly account for an array of potential genetic and environmental confounding factors. The co-twin control […]

Using Sucralose May Lead to Insulin Resistance in the Obese, Those Most Likely to Use the Sweetener

November 02, 2016 PracticeUpdate Editorial Team November 2, 2016—New Orleans, Louisiana— Sucralose may lead to insulin resistance in   people with obesity, according to new research from Washington University School of Medicine in St. Louis. The results were presented at ObesityWeek 2016, from October 31 – November 4. Marta Yanina Pepino de Gruev, PhD, now at […]