January 29, 2019 Brian A. Ference, MD, MPhil, MSc JAMA. 2019;321(4):364-373. doi:10.1001/jama.2018.20045 Key Points Question What is the clinical benefit of lowering plasma triglyceride levels compared with lowering low-density lipoprotein cholesterol levels? Findings In mendelian randomization analyses involving 654 783 participants, triglyceride-lowering variants in the lipoprotein lipase gene and low-density lipoprotein cholesterol (LDL-C)–lowering variants in the LDL receptor gene […]
JMPT November–December, 2018 Volume 41, Issue 9, Pages 771–779 Zhuomao Mo, BA Abstract Objective The purpose of this review was to compare oblique pulling spinal manipulation with other treatments for lumbar disc herniation. Methods Randomized controlled trials of oblique pulling manipulation versus other treatment for lumbar disc herniation were identified using the following databases: China […]
October 2, 2018 The ESCAPE Randomized Clinical Trial Victor A. van de Graaf, MD Key Points Question Is physical therapy noninferior to early surgery with arthroscopic partial meniscectomy for improving knee function among patients with nonobstructive meniscal tears? Findings In this noninferiority randomized clinical trial that included 321 patients, knee function that was measured by a self-administered […]
I’ve previously written about the question whether krill oil is, in fact, as the proper Latin name of the small critters it is made of, i.e. Euphausia superba, would suggest “superba”, ahh… I mean better than fish oil when it comes to its effects plasma and organ DHA and EPA. A large number of previous trials […]
Huisstede, Bionka M. et al. Archives of Physical Medicine and Rehabilitation , Volume 99 , Issue 8 , 1660 – 1680.e21 Abstract Objective To present an evidence-based overview of the effectiveness of surgical and postsurgical interventions for carpal tunnel syndrome (CTS). Data Sources The Cochrane Library, PubMed, EMBASE, CINAHL, and PEDro were searched for relevant […]
Di Yalong Arthritis Research & Therapy 2018 20:128 https://doi.org/10.1186/s13075-018-1621-0© The Author(s). 2018 Received: 16 September 2017Accepted: 13 May 2018 Published: 19 June 2018 Abstract Background In this study, we evaluated whether platelet-rich plasma (PRP) is superior to hyaluronic acid (HA) in the treatment of knee osteoarthritis. Methods The Cochrane Central Register of Controlled Trials, PubMed, […]
Cite this article as: Rastegar, S., Baradaran Mahdavi, S., Hoseinzadeh, B. et al. International Orthopaedics (SICOT) (2018) 42: 109. https://doi.org/10.1007/s00264-017-3681-1 Abstract Introduction Plantar fasciitis is a common cause of heel pain. Considering different interventions which are applied for patients with plantar fasciitis, dry needling is proposed as a new modality of treatment recently. The aim […]
Eur J Phys Rehabil Med. 2018 Apr 24. doi: 10.23736/S1973-9087.18.05005-0. [Epub ahead of print] Abstract BACKGROUND: Low back pain (LBP) is a common musculoskeletal disorder causing pain and disability in most of the countries. In recent years, new approaches such as Spinal manipulation and laser therapy have been considered as an alternative to conventional exercise […]
Musculoskeletal Science and Practice Volume 33, February 2018, Pages 67-70 Vahid Abdollah Highlights The signal intensity weighted centroid (SIWC) is a novel reliable non-invasive method for quantifying the effects of loading. Except for a more anterior SIWC in the L4L5 disc after extension, there were no significant SIWC differences. No significant differences were found in […]
Raveendhara R. Bannuru, MD, PhD Seminars in Arthritis & Rheumatism Published March 9, 2018 Abstract Purpose The unfavorable safety profiles of commonly prescribed knee osteoarthritis (OA) treatments have led clinicians and patients to seek safer alternatives. Research has suggested that curcuminoid and boswellia formulations could moderate key inflammatory pathways that are associated with worsening symptoms […]
February 20, 2018 The DIETFITS Randomized Clinical Trial Christopher D. Gardner, PhD JAMA. 2018;319(7):667-679. doi:10.1001/jama.2018.0245 Key Points Question What is the effect of a healthy low-fat (HLF) diet vs a healthy low-carbohydrate (HLC) diet on weight change at 12 months and are these effects related to genotype pattern or insulin secretion? Findings In this randomized clinical trial […]
by Hazel Smith, MedPage Today Staff February 26, 2018 Low-calorie lacto-ovo-vegetarian and Mediterranean diets appear to be equally effective in losing weight and reducing of certain risk factors in cardiovascular disease, a randomized trial found. This study — the first to directly compare the effects of these two eating patterns, the authors said — showed […]
Authors: David Griswold, PT, PhD Published: Journal of Orthopaedic & Sports Physical Therapy, 2018 Volume:0 Issue:0 Pages:1–30 DOI: 10.2519/jospt.2018.7738 Study Design Randomized clinical trial. Background The comparative effectiveness between non-thrust (NTM) and thrust manipulation (TM) for mechanical neck pain has been investigated with inconsistent results. Objective To compare the clinical effectiveness of concordant cervical and […]
Nancy S. Mansell, DPT The American Journal of Sports Medicine Article first published online: February 14, 2018 https://doi.org/10.1177/0363546517751912 Abstract Background: Arthroscopic hip surgery has risen 18-fold in the past decade; however, there is a dearth of clinical trials comparing surgery with nonoperative management. Purpose: To determine the comparative effectiveness of surgery and physical therapy for […]
Journal of Pain Research — | January 12, 2018 Raeissadat SA, et al. – This randomized clinical trial was planned to compare the efficacy of intra-articular ozone vs hyaluronic acid (HA) injection in patients with knee osteoarthritis (OA). Observations suggested that both ozone and HA can be effectively used for improving function and reducing pain […]
The Spine Journal Ian D. Coulter, Ph.D Background Context Mobilization and manipulation therapies are widely used to benefit patients with chronic low back pain. However, questions remain about their efficacy, dosing, safety, as well as how these approaches compare to other therapies. Purpose To determine the efficacy, effectiveness, and safety of various mobilization and manipulation […]