Published: Jul 9, 2014 By Sarah Wickline, Staff Writer, MedPage Today Story Source Journal Source See Also Natural Products as Aromatase Inhibitors Letrozole (Femara) used off-label to treat infertility outperformed first-line treatment clomiphene, with higher rates of live births in women with polycystic ovary syndrome, researchers reported. In a double-blind, randomized, multicenter trial with 750 women, […]
PracticeUpdate.com RESEARCH · July 08, 2014 TAKE-HOME MESSAGE This study investigated the association of regular use of NSAIDs with increased risk for cardiovascular events in postmenopausal women. Using data from the Women’s Health Initiative, investigators identified 53,142 women as regular NSAID users. Overall, NSAID use was associated with an increased hazard for cardiovascular events compared […]
Risk for Psoriasis Associated With Hypertension and Its Treatment RESEARCH · July 02, 2014 TAKE-HOME MESSAGE In this prospective cohort study using data from participants in the Nurses’ Health Study, the authors found a small, but significant, increased risk for psoriasis in individuals with hypertension for ≥6 years and in those on beta blockers for […]
Medscape.com theheart.org on Medscape > Trials and Fibrillations with Dr John Mandrola Growing Doubt on Statin Drugs: The Problem of Drug-Lifestyle Interaction John Mandrola July 02, 2014 Story Source Editor’s Note: This blog entry originally posted at drjohnm.org My mind is changing about statins. I’m growing increasingly worried about the irrational exuberance over these drugs, especially when used […]
John Mandrola July 02, 2014 Editor’s Note: This blog entry originally posted at drjohnm.org My mind is changing about statins. I’m growing increasingly worried about the irrational exuberance over these drugs, especially when used for prevention of heart disease that is yet to happen. An elderly patient called my office last week to tell me thank you . . . not for […]
Published: Jul 1, 2014 By John Fauber, Reporter, Milwaukee Journal Sentinel/MedPage Today; Kristina Fiore , Staff Writer, MedPage Today Story Source Overdose deaths from both prescription opioids and heroin continued to rise in 2011, the most recent year for which data were available, according to the CDC. While prescription opioid deaths followed a more […]
Medscape Medical News Marcia Frellick July 01, 2014 The benefits of routine childhood vaccines outweigh the risks of rare adverse events, according to results of a new systematic review. Although some vaccines are associated with serious adverse events, these events are extremely rare, the authors write. The researchers conducted a literature review of the safety […]
Medscape Medical News > Oncology Fran Lowry June 30, 2014 The longer a person takes low-dose aspirin, the lower the risk for pancreatic cancer, according to a study published online June 26 in Cancer Epidemiology, Biomarkers & Prevention. This finding adds to increasing evidence of the preventive properties of aspirin in pancreatic and other cancers, said senior author Harvey A. […]
by John Gever, Deputy Managing Editor, MedPage Today June 28, 2014 Danish children taking stimulant drugs for attention deficit-hyperactivity disorder (ADHD) had roughly double the risk for cardiovascular problems compared with other ADHD kids, a large registry study found, although the absolute incidence was still very low. Among some 714,000 Danish children born from 1990 […]
Is statin use associated with new joint-related symptoms, physical function and quality of life? The Australian Longitudinal Study on Women’s Health. Peeters G, et al. Arthritis Care Res (Hoboken). 2014 Jun 25. doi: 10.1002/acr.22389. [Epub ahead of print] Abstract Objectives Previous studies have suggested that statins may prevent development of osteoarthritis and have anti-inflammatory effects. […]
JAMA Intern Med. 2014 Jun;174(6):947-53. doi: 10.1001/jamainternmed.2014.946. Davidson BL1, Verheijen S2, Lensing AW3, Gebel M4, Brighton TA5, Lyons RM6, Rehm J7, Prins MH8. Abstract IMPORTANCE: Combined anticoagulant and aspirin therapy is associated with increased bleeding risk in patients with atrial fibrillation, but the bleeding risk of combined use of anticoagulant and nonsteroidal anti-inflammatory drugs (NSAIDs) […]
Medscape Medical News Janis C. Kelly June 18, 2014 Story Source Drug-induced liver injury is among the most challenging disorders for gastroenterologists to diagnose and treat, but the American College of Gastroenterology has issued new clinical guidelines to help physicians and other healthcare providers manage this disorder. The guidelines were published onlineJune 17 in the American Journal […]
Chen Q BMJ. 2014 Jun 18;348:g3769. doi: 10.1136/bmj.g3769. Abstract OBJECTIVE: To investigate the association between drug treatment for attention-deficit/hyperactivity disorder (ADHD) and risk of concomitant suicidal behaviour among patients with ADHD. DESIGN: Register based longitudinal study using within patient design. SETTING: Linkage of multiple national registers in Sweden. PARTICIPANTS: 37 936 patients with ADHD born between […]
Published: Jun 11, 2013 | Updated: Jun 12, 2013 By Todd Neale , Senior Staff Writer, MedPage Today Action Points Note that this cluster-randomized trial demonstrated that outpatient pediatric practices receiving triannual feedback regarding broad-spectrum antibiotic overuse significantly decreased their rate of prescribing these medications. Be aware that this difference was driven largely by a […]
Lee GC BMC Med. 2014 Jun 11;12(1):96. [Epub ahead of print] PubMed Reference Full Text Article Abstract BACKGROUND: The use of antibiotics is the single most important driver in antibiotic resistance. Nevertheless, antibiotic overuse remains common. Decline in antibiotic prescribing in the United States coincided with the launch of national educational campaigns in the 1990s […]
Published: Jun 9, 2014 | Updated: Jun 9, 2014 By Todd Neale, Senior Staff Writer, MedPage Today Action Points Note that this observational study suggested that users of statins had lower levels of physical activity than nonusers. Be aware that this finding does not necessarily imply that initiation of a statin will lead to lower […]
Date: June 2, 2014 Source: University of South Carolina Summary: Researchers have discovered a novel pathway through which marijuana’s main active constituent, THC, can suppress the body’s immune functions. The recent findings show that THC can change critical molecules of epigenome called histones, leading to suppression of inflammation. A team of University of South Carolina […]
The American Journal of Cardiology, 05/21/2014 Clinical Article Sharma A, et al. – The authors have evaluated incidence of new–onset AF with use of oral and intravenous bisphosphonates through a systematic review and meta–analysis of the literature. pooled data from randomized controlled trials (RCTs) and observational studies suggest that risk of AF is increased by […]