Medscape Medical News > Psychiatry Deborah Brauser May 23, 2014 Maternal antidepressant use may be associated with structural brain changes in infants, according to new imaging research. A retrospective cohort study of 33 children showed that the offspring of mothers who used selective serotonin reuptake inhibitors (SSRIs) during pregnancy were significantly more likely to develop […]
Medscape Medical News Marcia Frellick May 21, 2014 Physicians are prescribing antibiotics for acute bronchitis at rates between 60% and 80%, despite guidelines and educational efforts that say the rate should be zero, according to a research letter published in the May 21 issue of JAMA. For more than 40 years, the authors note, clinical trials have shown […]
Nonsteroidal Anti-Inflammatory Drugs Versus Corticosteroid for Treatment of Shoulder Pain: A Systematic Review and Meta-Analysis Xiao-Qing Zheng, MSc∗, Ke Li, MSc∗, You-Dong Wei, MD, PhD∗, Hong-Tao Tie, MSc, Xiao-Yan Yi, MSc, Wei Huang, MD, PhDemail ∗Zheng, Li, and Wei contributed equally to this work. Published Online: May 16, 2014 Objective To compare the treatment efficacy […]
Published: May 13, 2014 | Updated: May 14, 2014 By Michael Smith, North American Correspondent, MedPage Today Click Here For Story Source and VIDEO Action Points Note that this study of administrative data suggests a link between early antibiotic use and subsequent asthma in children. Be aware that causality can not be determined here; it […]
Published: May 7, 2014 | Updated: May 7, 2014 By Todd Neale, Senior Staff Writer, MedPage Today The FDA issued a message to consumers stating that the evidence does not support the “general” use of aspirin for the primary prevention of heart attacks and strokes. “In fact, there are serious risks associated with the use of […]
MedPageToday The FDA has denied a citizen’s petition from Bayer to add primary prevention of heart attacks and strokes to aspirin labeling. And then, the agency went directly to the public with a “consumer update” warning healthy people not to expect that daily aspirin will help them avoid cardiovascular events. FDA.gov On this page: Who Can Benefit? Caution […]
Published: Apr 30, 2014 By Elbert Chu The FDA failed to respond to a 2011 petition demanding strong warnings about proton pump inhibitors (PPIs), according to a Public Citizen’s lawsuit filed today. Public Citizen’s lawsuit seeks a ruling from the U.S. District Court of the District of Columbia that the FDA unlawfully withheld action, and calls for an […]
Research · April 29, 2014 TAKE-HOME MESSAGE This analysis of 15 case-control studies (n = 393,268) and 4 cohort studies found an increased risk of upper GI bleeding with selective serotonin reuptake inhibitors (SSRIs; OR, 1.66; 95% CI, 1.44–1.92). The addition of NSAIDs further increased this risk (OR, 4.25; 95% CI, 2.82–6.42). SSRIs modestly increase […]
Medscape Michael O’Riordan April 24, 2014 SAN DIEGO, CA — Individuals prescribed statin therapy for high cholesterol levels have increased their caloric intake by nearly 10% and their intake of fat by 14% over a recent 10-year period, while no changes in eating habits have been observed among statin nonusers, a new study shows[1]. In […]
Anne‐Marie Schjerning Olsen First published: 01 April 2014 https://doi.org/10.1111/bcpt.12243 Abstract This MiniReview describes the present evidence for the relationship between cardiovascular risk and use of non‐steroidal anti‐inflammatory drugs (NSAIDs) with special focus using Danish register‐based data. NSAIDs are among the most widely used drugs worldwide and mainly used for management of pain and inflammatory conditions. […]
Marlene Busko April 15, 2014 SEATTLE, WA — Patients receiving an anticoagulant for deep vein thrombosis (DVT) or pulmonary embolism (PE) who take a nonsteroidal anti-inflammatory drug (NSAID) or aspirin for pain or headache, even for a few days, are at heightened risk for a major bleed, according to a new study published online April […]
Research · April 14, 2014 TAKE-HOME MESSAGE In 966 mother–child pairs, including children with autism spectrum disorders (ASDs), developmental delays (DDs), and typical development (TD), boys with ASD were three times more likely than children with TD to have been prenatally exposed to selective serotonin reuptake inhibitors (SSRIs), and children with DDs were also more […]
Research · April 14, 2014 TAKE-HOME MESSAGE This study estimated the bleeding risk when the use of anticoagulant therapy (rivaroxaban or enoxaparin–vitamin K antagonist) was combined with either an NSAID or aspirin therapy in patients with VTE enrolled in clinical trials from 2007 to 2009. Clinically relevant bleeding was higher with combined use compared with anticoagulant use […]
Laurie Barclay, MD April 14, 2014 Prenatal use of selective serotonin reuptake inhibitors (SSRIs) appears to be a risk factor for autism spectrum disorders (ASDs) and other developmental delays (DDs) in young children, but underlying maternal depression may be a confounder, according to findings of a population-based case-control study published online April 14 in Pediatrics. “Serotonin is critical […]
The New York Times By CATHERINE SAINT LOUIS APRIL 13, 2014 Full Story Doctors are prescribing opioid painkillers to pregnant women in astonishing numbers, new research shows, despite the fact that risks to the developing fetus are largely unknown. Of 1.1 million pregnant women enrolled in Medicaid nationally, nearly 23 percent filled an opioid prescription in […]
Published: Apr 8, 2014 By Todd Neale, Senior Staff Writer, MedPage Today Full Story Journal Full Text Article Action Points Use of NSAIDs for 15 to 30 days was associated with an increased risk of atrial fibrillation compared with never-use. Additionally, recent use (within the prior 30 days but no current use) was associated with […]
PPIs, Mortality, and Rehospitalization in Older Patients Post Hospitalization RESEARCH · April 01, 2013 TAKE-HOME MESSAGE Use of proton pump inhibitors (PPIs) is associated with an increased risk of all-cause mortality in older patients discharged from acute care hospitals, even after adjusting for established predictors of adverse outcomes in this population, for whom physicians need […]