Diabetes

Nonnutritive Sweeteners in Weight Management and Chronic Disease – Full Text Article

April 17, 2018 TAKE-HOME MESSAGE The authors reviewed recent studies evaluating the effects of nonnutritive sweeteners (NNSs) on body weight and on chronic diseases related to obesity. There is a positive association seen between NNS and body weight and related health conditions in cross-sectional and prospective cohort studies. Cellular and rodent models indicate a possible […]

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8. Thaiss CA. Abstract Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse models of obesity and diabetes that hyperglycemia drives intestinal barrier permeability, through GLUT2-dependent transcriptional reprogramming of intestinal […]

Prediabetes tied to heart, kidney problems

MARCH 19, 2018 Reuters Health News Prediabetes may increase patients’ risk for heart and kidney disease, a US study suggests. As reported in The Lancet Diabetes and Endocrinology, online February 28, researchers examined a nationally representative sample of 27,971 adults surveyed in four waves from 1988 to 1994, 1999 to 2004, 2005 to 2010, and 2011 […]

ACP Recommends Less-Intensive HbA1c Target for T2D

by Jeff Minerd, Contributing Writer, MedPage Today March 05, 2018 New type 2 diabetes guidelines from the American College of Physicians (ACP) recommend less-intensive blood sugar control for most patients, with a glycated hemoglobin (HbA1c) target between 7% and 8%. “Studies have not consistently shown that intensive glycemic control to HbA1c levels below 7% reduces […]

The effects of folate supplementation on glucose metabolism and risk of type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials

Annals of Epidemiology — | February 26, 2018 Zhao JV, et al. – Folate, which reduces homocysteine, is promising for the prevention and treatment of diabetes. Previous meta-analysis of 3 trials suggested folate might lower hemoglobin A1c (HbA1c). In this current updated systematic review and meta-analysis of placebo-controlled randomized trials, a potential benefit of folate […]

Low Carb Diet Can Support Adults With T2D To Safely Improve HbA1c, Weight, and Reduce Medication Usage

Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year: An Open-Label, Non-Randomized, Controlled Study Cite this article as: Hallberg, S.J., McKenzie, A.L., Williams, P.T. et al. Diabetes Ther (2018). https://doi.org/10.1007/s13300-018-0373-9 Abstract Introduction Carbohydrate restriction markedly improves glycemic control in patients with type 2 diabetes (T2D) but […]

After a Year, Low-Carb Diet Helps Many Patients Reverse Type 2 Diabetes, Lose Weight, and Stop Insulin

February 12, 2018 Mary Caffrey Of the 262 patients with type 2 diabetes in the intervention, 83% stuck with it through the first year, despite significant requirements. Patients with type 2 diabetes (T2D) who spent a year limiting carbohydrates—while their biomarkers were closely watched to keep them in a metabolic state to burn fat—showed sharp […]

How fruit juice affects the gut

FEBRUARY 07, 2018 Healthline/Medical News Today It was previously believed that fructose, which is the sugar found in fruit and fruit juice, is processed by the liver. However, a new study suggests that fructose is mainly processed in the small intestine. The study, which is published in the journal Cell Metabolism, reveals that processed high-sugar food and […]

Glycosylated hemoglobin level may predict the severity of gastroparesis in diabetic patients

Diabetes Research and Clinical Practice Volume 135, January 2018, Pages 45-49 Manhal Izzy Highlights Higher glycated hemoglobin level is associated with slower gastric motility. Higher glycated hemoglobin level can be associated with worse gastroparetic symptoms. Intensive glycemic control might prevent or improve diabetic gastroparesis. Abstract Aim To investigate the association between glycemic control represented by glycated hemoglobin (HbA1c) level and the […]

The Answer to Diabetic Leg Pain?

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. One of the complications of diabetes is peripheral neuropathy. Peripheral neuropathy is a result of nerve damage which often causes weakness, numbness and pain, usually in your hands and feet. People generally describe the pain of peripheral neuropathy as tingling or burning as well as a loss of sensation […]

Ketogenic diet in endocrine disorders: Current perspectives

J Postgrad Med. 2017 Oct-Dec;63(4):242-251. doi: 10.4103/jpgm.JPGM_16_17. Gupta L, Khandelwal D, Kalra S, Gupta P, Dutta D5, Aggarwal S. Abstract Ketogenic diet (KD) is a high-fat, adequate-protein, and low-carbohydrate diet that leads to nutritional ketosis, long known for antiepileptic effects and has been used therapeutically to treat refractory epilepsy. This review attempts to summarize the […]

Pain sensation in human osteoarthritic knee joints is strongly enhanced by diabetes mellitus – Full Text Article

Eitner, Annetta; Pester, Juliab; Vogel, Franziskab; Marintschev, Ivanb; Lehmann, Thomasc; Hofmann, Gunther O.b,d; Schaible, Hans-Georga,* Pain: September 2017 – Volume 158 – Issue 9 – p 1743–1753 doi: 10.1097/j.pain.0000000000000972 Abstract: The major burden of knee joint osteoarthritis (OA) is pain. Since in elder patients diabetes mellitus is an important comorbidity of OA, we explored whether […]

Yoga Improves Glycemic Control in Adults With Type 2 Diabetes

September 26, 2017 Preventive Medicine TAKE-HOME MESSAGE The authors of this meta-analysis of 23 studies evaluated the effect of yoga on glycemic control in adults with type 2 diabetes (T2DM). Individuals participating in yoga had improved HbA1c, fasting blood glucose, post-prandial blood glucose, lipid profile, blood pressure, body mass index, waist/hip ratio, and cortisol levels […]

New study demonstrates an increase in HDL and lower lipoprotein(a) in type 2 diabetes patients with this nutritional intervention

Michael Jurgelewicz, DC, DACBN, DCBCN, CNS There are only a few natural products that have demonstrated such a wide range of protective properties as curcumin. Turmeric has three main bioactive components, namely curcumin, desmethoxycurcumin and bisdemethoxycurcumin. These curcuminoids have many biological effects including anti-inflammatory, antioxidant, antitumor, antibacterial, and antiviral properties. According to a new study […]

Very High Prevalence of Frozen Shoulder in Patients With Type 1 Diabetes of ≥45 Years’ Duration: The Dialong Shoulder Study

Niels Gunnar Juel, MD Archives of Physical Medicine and Rehabilitation August 2017 Volume 98, Issue 8, Pages 1551–1559 Highlights Of patients with type 1 diabetes for ≥45 years, 59% had frozen shoulder, with 73% affected bilaterally. Patients with painful frozen shoulder had highest disability and least shoulder mobility. High glycemic index was associated with severe disability […]

Broccoli in focus when new substance against diabetes has been identified

JUNE 22, 2017 University of Gothenburg The Sahlgrenska Academy News Researchers have identified an antioxidant – richly occurring in broccoli – as a new antidiabetic substance. A patient study shows significantly lower blood sugar levels in participants who ate broccoli extract with high levels of sulforaphane. “There are strong indications that this can become a […]

Cooking Methods for Red Meats Associated With Risk of Type 2 Diabetes

June 22, 2017 Diabetes Care TAKE-HOME MESSAGE Women aged 30 to 55 years without type 2 diabetes (T2D) were followed for a total of 1.24 million person-years to evaluate the association between cooking methods for red meats and the risk of T2D in women consuming two or more servings of red meat each week. There […]

Correcting Vitamin D Deficiency May Improve Glycemic Control in Type 2 Diabetes

June 20, 2017 TAKE-HOME MESSAGE The authors of this systematic review and meta-analysis sought to determine if vitamin D supplementation influenced glycemic control in type 2 diabetes patients. The researchers found that supplementation with vitamin D was associated with lower HbA1c levels but not lower fasting blood glucose. However, in a subgroup of patients with […]

Moderate Wine-Drinking Benefits Extend to Type 2 Diabetes

Miriam E. Tucker March 18, 2014 Moderate wine drinking is associated with reduced risks for cardiovascular events and all-cause mortality among patients with type 2 diabetes, according to a new analysis of data from the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial. The results were published online February […]

Capsaicin 8% Patch Is Effective in Painful Diabetic Peripheral Neuropathy

March 20, 2017 The Journal of Pain TAKE-HOME MESSAGE In this study, 369 patients with painful diabetic peripheral neuropathy and stable HbA1c scores <11% were randomized to receive a one-time, 30-minute application of the 8% capsaicin patch or a placebo patch to a painful area on the foot. Patients then reported pain and sleep at […]