By CATHERINE SAINT LOUIS JANUARY 5, 2015 The Food and Drug Administration has raised new questions about the safety of an adult laxative routinely given to constipated children, sometimes daily for years. The agency has asked a team of scientists in Philadelphia to look more closely at the active ingredient in Miralax and similar generic products, called polyethylene […]
Ricki Lewis, PhD December 19, 2014 Story Source Nonsteroidal anti-inflammatory drugs (NSAIDs) may protect against skin cancer, according to a study published online December 18 in the Journal of Investigative Dermatology. NSAID use has been associated with lowered risk for colon, lung, breast, and prostate cancers, but evidence for preventing skin cancer has been inconclusive. Chiho Muranushi, PhD, from the […]
Cautions against the practice go unheeded by nonpsychiatrists. by John Gever Managing Editor, MedPage Today About one in 12 older Americans were prescribed benzodiazepines in 2008, and one-third of those individuals took them for long periods — and much of this use was probably inappropriate, researchers said. Analysis of a large prescription database for 2008 […]
Ricki Lewis, PhD Story Source December 19, 2014 Nonsteroidal anti-inflammatory drugs (NSAIDs) may protect against skin cancer, according to a study published online December 18 in the Journal of Investigative Dermatology. NSAID use has been associated with lowered risk for colon, lung, breast, and prostate cancers, but evidence for preventing skin cancer has been inconclusive. Chiho Muranushi, PhD, from the […]
Painkiller Tramadol Linked to Low Blood Sugar Study finds the drug may be riskier than expected By Steven Reinberg HealthDay Reporter MONDAY, Dec. 8, 2014 (HealthDay News) — The narcotic painkiller tramadol (Ultram) seems to be associated with an increased risk of dangerously low blood sugar, Canadian researchers report. Tramadol is a narcotic drug whose […]
Frontline Medical News, 2014 Nov 17, A Karon Story Source Taking nonsteroidal anti-inflammatory drugs for 14 days more than doubled the risk of serious bleeding in patients with atrial fibrillation, and it increased the risk of thromboembolism by 36%, according to a report published online Nov. 17 in Annals of Internal Medicine. Risk of serious […]
Pauline Anderson November 28, 2014 Epidural steroid injections (ESIs) should be contraindicated under certain circumstances in the management of back pain, the US Food and Drug Administration’s (FDA’s) Anesthetic and Analgesic Drug Products Advisory Committee has concluded. After 2 days of presentations and discussions, committee members agreed that injecting a particulate steroid in the cervical […]
November 26, 2014 Annals of Internal Medicine TAKE-HOME MESSAGE The authors of this observational cohort study of over 150,000 Danish patients with atrial fibrillation (AF) hospitalized from 1997 to 2011 examined the risk for serious bleeding and thromboembolism associated with NSAID and antithrombotic therapy. At 3 months, the absolute risk difference for serious bleeding in […]
Frontline Medical News, 2014 Nov 17, A Karon Taking nonsteroidal anti-inflammatory drugs for 14 days more than doubled the risk of serious bleeding in patients with atrial fibrillation, and it increased the risk of thromboembolism by 36%, according to a report published online Nov. 17 in Annals of Internal Medicine. Risk of serious bleeding and […]
Lara C. Pullen, PhD November 19, 2014 The adverse effects of amoxicillin appear to be underreported in clinical trials. In particular, treatment with amoxicillin-clavulanic acid commonly results in diarrhea, and treatment with amoxicillin-clavulanic acid or amoxicillin commonly results in candidiasis. Malcom Gillies, PhD, from NPS Medicine Wise, Sydney, New South Wales, Australia, and colleagues published their […]
Pam Harrison November 18, 2014 Exposure to antibiotics during childhood significantly increases the risk for juvenile idiopathic arthritis in a dose-dependent manner, say investigators reporting at the American College of Rheumatology 2014 Annual Meeting in Boston. They suggest that alterations in the human microbiome might be implicated in the development of the disease. “The more […]
Susan Jeffrey November 18, 2014 Story Source CHICAGO — A new trial shows no benefit of low-dose, once-daily aspirin in the primary prevention of cardiovascular events in patients with multiple risk factors, including hypertension, diabetes, and dyslipidemia. No benefit was seen for the composite endpoint of nonfatal myocardial infarction (MI), nonfatal stroke, or death from […]
Use of often prescribed drugs against arthritis and pain increases the risk of dying from a stroke. This is the conclusion of a major new registry study involving more than 100,000 patients. 2014.11.13 | LOTTE FISKER JØRGENSEN It is older versions of COX-2 inhibitors, which are now linked to increased risk of dying from a […]
Benzodiazepine use and risk of Alzheimer’s disease: case-control study BMJ, 11/09/2014 Clinical Article Abstract Objectives To investigate the relation between the risk of Alzheimer’s disease and exposure to benzodiazepines started at least five years before, considering both the dose-response relation and prodromes (anxiety, depression, insomnia) possibly linked with treatment. Design Case-control study. Setting The Quebec […]
COX-2 Inhibitors Linked to Stroke Mortality Sue Hughes November 06, 2014 Further evidence suggesting harm of cyclooxygenase-2 (COX-2) inhibitors in patients with stroke has been reported, with this latest study showing these agents to be associated with an increased risk for stroke mortality. The study, published online in Neurology on November 5, was conducted by a team led by […]
ISSUE: NOVEMBER 2014 | VOLUME: 12(11) The FDA’s warning that use of epidural steroid injections (ESIs) may result in “rare but serious adverse events, including loss of vision, stroke, paralysis and death” drew a strong response from societies whose members offer such pain treatments. The FDA required the addition of a warning to the labels […]
Published: Nov 5, 2014 By Nancy Walsh, Senior Staff Writer, MedPage Today The regular use of statins, particularly among women, was associated with an increased risk of thyroid cancer, Taiwanese researchers reported. Compared with controls, patients who routinely used statins had an adjusted odds ratio for having thyroid cancer of 1.40 (95% CI 1.05-1.86, P<0.05), according […]