Med Sci Monit. 2014 Nov 6;20:2183-8. doi: 10.12659/MSM.890777. Coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study. Skarlovnik A, Janić M, Lunder M, Turk M, Šabovič M. Abstract BACKGROUND: Statin use is frequently associated with muscle-related symptoms. Coenzyme Q10 supplementation has yielded conflicting results in decreasing statin myopathy. Herein, we tested whether […]
Anesthesiology. 2014 Nov;121(5):1045-55. doi: 10.1097/ALN.0000000000000409. Epidural Steroid Injections, Conservative Treatment, or Combination Treatment for Cervical Radicular Pain: A Multicenter, Randomized, Comparative-effectiveness Study. Cohen SP1, Hayek S, Semenov Y, Pasquina PF, White RL, Veizi E, Huang JH, Kurihara C, Zhao Z, Guthmiller KB, Griffith SR, Verdun AV, Giampetro DM, Vorobeychik Y. Abstract BACKGROUND: Cervical radicular pain […]
J Gen Intern Med. 2014 Oct 30. [Epub ahead of print] A Partnered Approach to Opioid Management, Guideline Concordant Care and the Stepped Care Model of Pain Management. Dorflinger L, Moore B, Goulet J, Becker W, Heapy AA, Sellinger JJ, Kerns RD. Abstract BACKGROUND: Pain is the most common presenting problem in primary care. Opioid […]
AN EXPERT INTERVIEW WITH CHARLES H. HENNEKENS, MD, DRPH Linda Brookes, MSc, Charles H. Hennekens, MD, DrPH October 29, 2014 OUR ROLLERCOASTER RELATIONSHIP WITH ASPIRIN Opinions on the use of aspirin in the prevention of cardiovascular disease (CVD) have varied over the past 25 years since the Physicians’ Health Study (PHS) first demonstrated conclusively that […]
Jenni Laidman October 27, 2014 Ibuprofen proved just as effective as morphine for pain control in children with uncomplicated fractures, and it brought on significantly fewer adverse effects, according to a study published online October 27 in the Canadian Medical Association Journal. In a parallel-group, randomized, blinded superiority trial, Naveen Poonai, MD, from the Division of […]
Megan Brooks October 21, 2014 Nonsteroidal anti-inflammatory drugs (NSAIDs) may help ease depressive symptoms, new research suggests. Results of a meta-analysis show that the adjunctive use of NSAIDs was associated with improved antidepressant treatment response without an increased risk for adverse effects. In particular, add-on treatment with celecoxib (Celebrex, GD Searle LLC) improved antidepressant effects, […]
Medscape Medical News from the: 27th European College of Neuropsychopharmacology (ECNP) Congress Medscape Medical News > Psychiatry Antidepressants Blunt Sexual Function, Feelings of Love Deborah Brauser October 20, 2014 BERLIN ― Long-term antidepressant use may be associated with significant “emotional blunting” in both male and female patients ― but in different ways, new research suggests. […]
Tae Kang Lim, MD; Kyoung Hwan Koh, MD; Min Soo Shon, MD; Seung Won Lee, MD; Young Eun Park, MD; Jae Chul Yoo, MD Orthopedics October 2014 – Volume 37 · Issue 10: e860-e865 DOI: 10.3928/01477447-20140924-51 Abstract The goal of this study was to prospectively compare the early clinical results of intra-articular injection of hyaluronate […]
Ricki Lewis, PhD Story Source October 03, 2014 Medications are the leading cause of anaphylaxis-related deaths, especially among older individuals and blacks, according to a study published onlineSeptember 30 in the Journal of Allergy and Clinical Immunology. The United States does not maintain a national registry to track fatal anaphylaxis. To understand the temporal patterns and demographic associations of such […]
An analysis of data on nearly 15,000 patients found that treatment with beta-blockers was linked to a higher risk of stroke among patients with multiple heart disease risk factors but no history of a cardiovascular event. Researchers also found that use of beta-blockers was not linked to lower cardiovascular events in those with no history […]
Published: Sep 29, 2014 By Michael Smith, North American Correspondent, MedPage Today Children exposed repeatedly to antibiotics in their first 2 years of life were more likely to be obese later in childhood, researchers said. Children with four or more courses of antibiotics were 11% more likely than others to become obese, according toCharles Bailey, […]
Larry Hand September 25, 2014 Story Source Nonsteroidal anti-inflammatory drugs (NSAIDs) may almost double the risk for venous thromboembolism (VTE), including deep venous thrombosis and pulmonary embolism, according to an article published online September 24 in Rheumatology. “[T]he results of our meta-analysis demonstrate a statistically significantly increased VTE risk among NSAID users. Physicians should be […]
The American Journal of Gastroenterology , (16 September 2014) | doi:10.1038/ajg.2014.233 A Prospective Study of the Effect of Bowel Movement Frequency, Constipation, and Laxative Use on Colorectal Cancer Risk Jessica Citronberg, Elizabeth D Kantor, John D Potter and Emily White Abstract OBJECTIVES: Constipation and laxative use have been hypothesized to increase colorectal cancer (CRC) risk, […]
Gwen M.C. Masclee Gastroenterology Volume 147, Issue 4, Pages 784–792.e9, October 2014 Background & Aims Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs) and low-dose aspirin increases the risk of upper gastrointestinal bleeding (UGIB). Guidelines suggest avoiding certain drug combinations, yet little is known about the magnitude of their interactions. We estimated the risk of UGIB […]
Published: 24 September 2014 Scottish researchers have identified how cholesterol-lowering drugs increase the chances of patients developing diabetes, but say the benefits of treatment still far outweigh the risks. The team from Glasgow University calculated that use of statins increased the risk of type-2 diabetes by around 12 per cent after four years. Those taking […]
Medscape Medical News from: The American Society for Bone and Mineral Research (ASBMR) 2014 Story Source September 22, 2014 HOUSTON, Texas — Use of hypnotic medications for insomnia and use of selective serotonin reuptake inhibitors (SSRIs) are each associated with an increased risk for osteoporotic and hip fractures in older women and men, independent of other risk factors on […]
Deaths From Narcotic Painkillers Quadrupled in Past Decade: CDC Increases highest among whites, and people between 55 and 64 By Steven Reinberg HealthDay Reporter Story Source TUESDAY, Sept. 16, 2014 (HealthDay News) — The number of Americans dying from accidental overdoses of narcotic painkillers jumped significantly from 1999 to 2011, federal health officials reported Tuesday. […]