Menopausal hormone use and ovarian cancer risk: individual participant meta-analysis of 52 epidemiological studies The Lancet, 02/17/2015 Half the epidemiological studies with information about menopausal hormone therapy and ovarian cancer risk remain unpublished, and some retrospective studies could have been biased by selective participation or recall. Authors aimed to assess with minimal bias the effects […]
Risk, though small, appears highest when medications given in first 6 weeks, researchers report Monday, February 16, 2015 MONDAY, Feb. 16, 2015 (HealthDay News) — Using certain antibiotics early in infancy may raise the risk of a serious gastrointestinal condition called pyloric stenosis, a new study indicates. Doctors have known that using the antibiotic erythromycin […]
02.16.2015 Action Points Note that this randomized trial of hyaluronic acid versus betamethasone, injections for knee osteoarthritis demonstrated that effects at 1 year were superior in the hyaluronic acid arm. Be aware that significant differences in BMI between the groups leads to some concern about randomization quality. Intra-articular injections of both hyaluronic acid and steroids […]
Date: February 10, 2015 Source: Oregon State University Summary: Researchers have discovered that antibiotics have an unwanted impact on the microorganisms that live in an animal’s gut that’s more broad and complex than previously known. A study has helped to explain these processes, which are now believed to affect everything from the immune system to […]
— A new meta-analysis examines hyaluronic acid for treating knee OA. by Hilda Bastian February 3, 2015 Is hyaluronic acid (HA) just an expensive placebo treatment with adverse effects? Or can HA injections into knees damaged by osteoarthritis improve lubrication and shock absorption? Whatever your position has been — for, against, or on the fence […]
January 26, 2015 Journal of the American College of Cardiology Volume 65, Issue 2, January 2015 Ravi S. Hira, MD TAKE-HOME MESSAGE Using a US nationwide registry, the authors examined the frequency and practice-level variation of inappropriate aspirin use for preventing cardiovascular disease (CVD). Overall, the frequency of inappropriate aspirin use was 11.6% (N = […]
Sue Hughes January 27, 2015 A new study provides the strongest evidence that anticholinergic drugs may increase the risk for dementia in older adults. The drugs implicated are commonly used, estimated to be taken by about 20% of the older adult population for many conditions. They include popular antihistamines sold over the counter as sleep aids, such […]
Richard C. Dart, M.D. January 15, 2015 N Engl J Med 2015; 372:241-248 Abstract / Article Extract Background The use of prescription opioid medications has increased greatly in the United States during the past two decades; in 2010, there were 16,651 opioid-related deaths. In response, hundreds of federal, state, and local interventions have been implemented. […]
Fran Lowry January 22, 2015 An association between hormonal contraceptives and an increased risk for glioma in younger women has been found in a Danish nationwide case–control study. That risk increases with the duration of use, David Gaist, MD, from Odense University Hospital and the University of South Denmark, and colleagues report in their study, published today […]
Megan Brooks January 22, 2015 Opioid pain medications are widely prescribed among women of childbearing age, which is a “significant public health concern,” federal health officials with the Centers for Disease Control and Prevention said today. A new report published in the January 23 issue ofMorbidity and Mortality Weekly Report (MMWR) shows that roughly one fourth of privately insured women […]
Posted on June 14, 2004 by Sally Fallon and Mary G. Enig, PhD Hypercholesterolemia is the health issue of the 21st century. It is actually an invented disease, a “problem” that emerged when health professionals learned how to measure cholesterol levels in the blood. High cholesterol exhibits no outward signs–unlike other conditions of the blood, such as […]
By Benjamin Fearnow June 19, 2013 Rochester, Minn. (CBS ATLANTA) – Researchers find that nearly 70 percent of Americans are on at least one prescription drug, and more than half receive at least two prescriptions. Mayo Clinic researchers report that antibiotics, antidepressants and painkiller opioids are the most common prescriptions given to Americans. Twenty percent […]
January 16, 2015 The American Journal of Cardiology TAKE-HOME MESSAGE In this prospective study, researchers evaluated 4645 patients with vascular disease to determine the association between statin use and incident type 2 diabetes mellitus. Independent from metabolic syndrome characteristics, statin therapy, especially intensive statin therapy, was associated with an increased risk for type 2 diabetes. […]
January 14, 2015 Annals of Internal Medicine TAKE-HOME MESSAGE In this meta-analysis, researchers assessed 137 studies to determine the efficacy of treatments for knee osteoarthritis. Hyaluronic acid was considered the most effective for pain control, and acetaminophen was considered the least effective. Intra-articular corticosteroids did not improve function when compared with placebo, and none of […]
Friday 16 January 2015 Alan Yuhas in New York In 2012, Americans received nearly 260 million prescriptions for opiate painkillers. Now, the National Institutes of Health (NIH) has released a white paper that reports “a dire need for research” to make up for the “scant” evidence that opioid painkillers should be used to treat chronic pain. The […]
January 15, 2015 Frontline Medical News Eczema in adulthood is directly associated with an increase in incidence of injuries that cause physical limitations, particularly fracture, bone, and joint injuries, according to the results of a prospective study published online in JAMA Dermatology. “The risk of bone fracture and other injury causing limitation in adults with […]
January 12, 2015 Annals of Oncology TAKE-HOME MESSAGE Investigators in this case-control study in Denmark evaluated the association between daily low-dose aspirin and the risk for developing ovarian cancer. The findings suggest that low-dose aspirin, especially continuous, long-term use, may be associated with a reduced risk for developing epithelial ovarian cancer. Further studies are needed […]
Megan Brooks DisclosuresJanuary 09, 2015 In a drug safety communication issued today, the US Food and Drug Administration (FDA) says it is aware of recent reports “questioning” the safety of prescription and over-the-counter (OTC) pain medicines when used during pregnancy, but that it lacks adequate studies to change current recommendations. The benefits and risks of using prescription […]
Ricki Lewis, PhD January 07, 2015 Despite the prevalence of knee osteoarthritis (OA), few studies compare treatments head-to-head. Now, a network meta-analysis compares 137 reports on the effectiveness of such treatments and reveals that acetaminophen, the most widely used over-the-counter treatment, does not provide a clinically significant reduction in pain. “Except for celecoxib, all active interventions were […]
January 07, 2015 JAMA TAKE-HOME MESSAGE The authors of this JAMA clinical synopsis examine whether antibiotics are associated with improved outcomes in patients with acute bronchitis. While antibiotic use was associated with reduced overall and nighttime cough and slight reductions in duration of cough, feeling ill, and impaired activities, patients taking antibiotics had no significant […]