Don’t expect relief to last beyond a few months by Nancy Walsh, Senior Staff Writer, MedPage Today March 29, 2019 Pain relief from nonsteroidal anti-inflammatory drugs (NSAIDs) in knee osteoarthritis (OA) was rapid but declined over time, a large meta-analysis demonstrated. Data from 72 randomized controlled trials found that statistically significant reductions in pain peaked […]
Benjamin J. Sherman, DO; Jorge Chahla, MD, PhD; Jason Glowney, MD; Rachel M. Frank, MD Orthopedics. 2019;42(2):66-73https://doi.org/10.3928/01477447-20190225-02 Posted March 21, 2019 Abstract Individuals with osteoarthritis have a diminished quality of life, and the condition is a major cause of disability. Newer biologic treatments have been developed that are believed to modify disease progression. These predominantly […]
Fran Lowry March 19, 2019 DENVER — Chiropractic care for musculoskeletal pain is associated with a significant reduction in opioid prescriptions compared with non-chiropractic care in this patient population, new research suggests. In a new meta-analysis and systematic review, patients who visited a chiropractor for a musculoskeletal pain condition were 49% less likely to receive […]
March 25, 2019 LAS VEGAS — Although corticosteroid injections appear to offer short-term benefits regarding pain and function for patients with knee arthritis, a presenter here noted no guidance is available in the terms of frequency and dosage. In his presentation at The Knee Society Specialty Day at the American Academy of Orthopedic Surgeons Annual […]
Janis C. Kelly February 08, 2019 Patients with mild to moderate knee osteoarthritis (KOA) who used intra-articular corticosteroids (IACs) experienced substantially faster disease progression than those in a matched group who had not received IACs. However, experts caution that the difference in progression rates might reflect underlying differences that influenced the decision to treat with IACs. Thus, […]
Osteoarthritis and Cartilage — Thorlund JB, et al. | January 24, 2019 In this study, researchers quantified opioid use in patients with knee and hip osteoarthritis (OA), and calculated the proportion of opioids in the population attributable to patients with OA. Study participants included 751,579 inhabitants of southern Sweden aged ≥ 35 years (in 2015). […]
Sue Hughes January 23, 2019 A new meta-analysis of trials evaluating aspirin for primary prevention of cardiovascular disease has found no overall benefit, with aspirin use associated with a lower risk of cardiovascular events but an increased risk of major bleeding, and no effect of aspirin on cancer risk. However, there still appears to be some disagreement […]
The Spine Journal Volume 18, Issue 11, November 2018, Pages 1974-1981 The Spine Journal Clinical Study Andrew J.Pugely MD Abstract Background Context Limited or no data exist evaluating risk factors associated with prolonged opioid use following cervical arthrodesis. Purpose The objectives of this study were to assess trends in postoperative narcotic use among preoperative opioid […]
Popular pain drug linked to rise in overdoses, suicides By Liam Mannix & Aisha Dow 26 November 2018 — 1:11am It has become one of Australia’s most popular pharmaceutical drugs, seen by some GPs as a safer alternative to opioid painkillers. But an explosion of overdoses and deaths has led to growing concern about the […]
Am J Med Sci. 2014 Mar;347(3):211-6. doi: 10.1097/MAJ.0b013e31828318e2. Magulick JP1, Frei CR, Ali SK, Mortensen EM, Pugh MJ, Oramasionwu CU, Daniels KR, Mansi IA. Abstract BACKGROUND: Statins have been postulated to prevent infection through immunomodulatory effects. OBJECTIVES: To compare the incidence of infections in statin users to that in nonusers within the same health care […]
By Lorraine L. Janeczko October 24, 2018 NEW YORK (Reuters Health) – Patients with osteoarthritis who start opioid treatment at higher doses tend to have higher treatment-failure rates, according to an industry-sponsored study. The findings were presented in a poster September 13 at the International Association for the Study of Pain (IASP) World Congress on […]
Payers that cover physical therapy and chiropractic care for addressing lower back pain can lower costs and opioid use. By Thomas Beaton October 23, 2018 – Payers could improve outcomes, increase cost-effectiveness, and reduce opioid use for lower back pain by expanding non-pharmacological coverage such as physical therapy and chiropractic care, according to a new […]
Reuters Health News | September 28, 2018 Cannabinoid drugs may reduce or prevent pain by producing small increases in pain thresholds, rather than by reducing the intensity of experimental pain that is already being experienced, researchers say. “We meta-analyzed the results from every available experimental pain trial, and found that numerous aspects of pain were […]
American Journal of Cardiovascular Drugs — Martinez AI, et al. | September 27, 2018 In this retrospective cohort study, researchers used data from the Truven Health MarketScan Research Database (2009–2015) to determine the risk of gastrointestinal (GI) hemorrhage in statin users aged 30–65 years at initial prescription claim. Study participants, negative control participants (ie, other […]
September 25, 2018 Paulina Salminen, MD, PhD1,2; Risto Tuominen, MPH, PhD3,4,5; Hannu Paajanen, MD, PhD6; et al Tero Rautio, MD, PhD7; Pia Nordström, MD, PhD8; Markku Aarnio, MD, PhD9; Tuomo Rantanen, MD, PhD10,11,12; Saija Hurme, MSc13; Jukka-Pekka Mecklin, MD, PhD14,15; Juhani Sand, MD, PhD16; Johanna Virtanen, MD, PhD17; Airi Jartti, MD, PhD18; Juha M. Grönroos, […]
Reuters Health News | September 24, 2018 The commonly used painkiller diclofenac may be linked with an increased risk of heart problems, a large Danish study suggests. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that’s often used to treat arthritis and other painful joint conditions. In many countries, it’s available without a prescription. Researchers found […]
Pain Med. 2018 Sep 1;19(suppl_1):S54-S60. doi: 10.1093/pm/pny114. Lisi A Abstract OBJECTIVE: To examine patient sociodemographic and clinical characteristics associated with opioid use among Veterans of Operations Enduring Freedom/Iraqi Freedom/New Dawn (OEF/OIF/OND) who receive chiropractic care, and to explore the relationship between timing of a chiropractic visit and receipt of an opioid prescription. METHODS: Cross-sectional analysis […]
Retrospective Australian data suggest association with rare but severe condition by Nicole Lou, Contributing Writer, MedPage Today July 30, 2018 Autoimmune muscle inflammation was more likely to turn up among patients using statins than those not on these medications, according to an Australian population-based study. Statin use was seen in 30.8% of patients at the […]