JAMA internal medicine TAKE-HOME MESSAGE Researchers retrospectively evaluated 754 patients with healthcare-associated Clostridium difficile infection to determine the association of proton pump inhibitor use (PPI) with recurrence. The hazard ratio for recurrence was 1.5 for continuous PPI use, and 47.1% of patients receiving PPIs had an evidence-based indication. Researchers suggest that PPI use without proper […]
George Du Toit, M.B., B.Ch. February 26, 2015 N Engl J Med 2015; 372:803-813 Abstract BACKGROUND The prevalence of peanut allergy among children in Western countries has doubled in the past 10 years, and peanut allergy is becoming apparent in Africa and Asia. We evaluated strategies of peanut consumption and avoidance to determine which strategy […]
BY JANICE NEUMANN Fri Feb 27, 2015 12:13pm EST (Reuters Health) – Excess pounds and smoking might each raise the likelihood of frequent heartburn or gastroesophageal reflux disease (GERD), according to a large study from Norway. Other factors linked to higher odds of new GERD symptoms included getting older, being a woman, having less education, […]
The New England Journal of Medicine N Engl J Med 2015; 372:825-834February 26, 2015DOI: 10.1056/NEJMoa1408913 TAKE-HOME MESSAGE The authors of this study performed active surveillance across 10 geographic areas of the United States in 2011 to identify stool-positive cases of Clostridium difficile infection and classify them as community-associated or healthcare-associated. Of the total of 15,461 […]
CATHERINE GUTHRIE · MARCH 2015 Your intestines are home to a great deal of your digestive system, nervous system, and immune system. Here’s how to keep them healthy. Modern life is hard on your gut. Your entire digestive tract can be affected by stress, processed foods, alcohol, medications, and bacteria. All that chronic irritation can lead to inflammation and, […]
by Nancy Walsh Senior Staff Writer, MedPage Today Action Points In young children at high risk for peanut allergy, early oral exposure to peanuts is associated with markedly lower likelihood of actually developing peanut allergy. Levels of peanut-specific IgG4 and IgG were higher in those consuming than in those avoiding peanuts, an effect that mimics […]
The Need for a Diverticulitis Diet Diverticulitis is a painful and upsetting disturbance in the digestive tract, a colon disease, which can be effectively treated with the diverticulitis diet. While some individuals experience constant discomfort, others experience diverticulitis that wanes, and then flares up. Diet, and a variety of risk factors can increase your chances of […]
Risk, though small, appears highest when medications given in first 6 weeks, researchers report Monday, February 16, 2015 MONDAY, Feb. 16, 2015 (HealthDay News) — Using certain antibiotics early in infancy may raise the risk of a serious gastrointestinal condition called pyloric stenosis, a new study indicates. Doctors have known that using the antibiotic erythromycin […]
February 12, 2015 TAKE-HOME MESSAGE Emerging immunotherapies can be administered orally and have shown potential in the treatment of peanut, egg, and milk allergies. The authors describe the complexity of IgE-mediated allergies to food and summarize the therapies currently undergoing clinical trials. Written by Benjamin Wright MD Dramatic increases in the number of individuals […]
Date: February 10, 2015 Source: Oregon State University Summary: Researchers have discovered that antibiotics have an unwanted impact on the microorganisms that live in an animal’s gut that’s more broad and complex than previously known. A study has helped to explain these processes, which are now believed to affect everything from the immune system to […]
Risk Factors on the Development of New-Onset Gastroesophageal Reflux Symptoms. A Population-Based Prospective Cohort Study: The HUNT Study Andreas Hallan BSc, Med Am J Gastroenterol advance online publication 10 February 2015; doi: 10.1038/ajg.2015.18 Abstract Objectives: Gastroesophageal reflux disease (GERD) is a highly prevalent disorder. This study assessed the risk factors of new-onset gastroesophageal reflux symptoms […]
Date: February 5, 2015 Source: Broad Institute of MIT and Harvard Summary: In one of the largest longitudinal studies of the microbiome to date, researchers have identified a connection between changes in gut microbiota and the onset of type 1 diabetes. The study, which followed infants who were genetically predisposed to the condition, found that […]
February 03, 2015 Diagnosis and Treatment of Clostridium difficile in Adults JAMA : The Journal of the American Medical Association TAKE-HOME MESSAGE In this systematic review, 116 articles were analyzed to determine the best practices for Clostridium difficile (CDI) diagnosis and treatment in adults. Although C. difficile diagnostic testing is sometimes complex, several treatment options […]
Beyond bacteria: The gut virome in inflammatory bowel disease patients differed from those without the disease, researchers reported in Cell. Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease Jason M. Norman Highlights • The enteric virome is abnormal in multiple inflammatory bowel disease patient cohorts • The enteric virome richness increases in Crohn’s […]
January 29, 2015 Gastroenterology TAKE-HOME MESSAGE The authors review diet in the management of inflammatory bowel disease (IBD). Studies regarding the effect of food on IBD are discussed. Overall, authors found that components of some whole foods can cause IBD symptoms, whereas some nutrients may decrease inflammation of the intestines. Specific diets may improve the […]
January 28, 2015 Nutrients, Foods, and Colorectal Cancer Prevention Gastroenterology TAKE-HOME MESSAGE Epidemiological and experimental studies over the years have linked several foods to risk of colorectal cancer. Foods associated with lower risk include calcium, fiber, milk, and whole grains. Foods associated with higher risk include red meat and processed meat. Chemopreventive effects are attributed […]
Am J Gastroenterol advance online publication 27 January 2015; doi: 10.1038/ajg.2014.427 Mirjana Rajilić-Stojanović PhD Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena? Abstract Irritable bowel syndrome (IBS) is a heterogeneous functional disorder with a multifactorial etiology that involves the interplay of both host and environmental factors. Among environmental factors relevant for IBS etiology, […]
By Dr. Davis | January 8, 2015 If you want type 2 diabetes , follow conventional advice to cut fat and eat more “healthy whole grains.” (This is also true for type 1 diabetes in susceptible individuals with pancreatic beta cell autoimmunity triggered by wheat gliadin or corn zein.) But what if you don’t want to […]
— The intestinal microbiota may act as a trigger in pediatric enthesitis-related arthritis. by Nancy Walsh, Senior Staff Writer, MedPage Today December 3, 2014 Alterations in the intestinal microbiota have been identified in children with enthesitis-related arthritis (ERA), suggesting the possibility that the microbiome may play a triggering role in the disease, researchers reported. Among […]