A double blind, placebo, controlled randomized clinical trial In a randomized, double-blind, placebo-controlled study involving 48 patients with relapsing-remitting multiple sclerosis (MS), supplementation with coenzyme Q10 (500 mg/d) for a period of 12 weeks was found to be associated with significant reductions in inflammatory markers – TNF-alpha, IL-6, and serum MMP-9 (matrix metalloproteinase), as compared […]
Effects of coenzyme Q10 supplementation (300 mg/day) on antioxidation and anti-inflammation in coronary artery disease patients during statins therapy A randomized, placebo-controlled trial Lee BJ, Tseng YF, Yen CH, Lin PT. Abstract BACKGROUND: High oxidative stress and chronic inflammation can contribute to the pathogenesis of coronary artery disease (CAD). Coenzyme Q10 is an endogenous lipid-soluble […]
Baek D, Park Y. Abstract Associations between n-3 polyunsaturated fatty acids (PUFAs), inflammation, oxidative stress and the risk of depression have been suggested. We hypothesize that erythrocyte n-3 PUFAs are inversely associated with biomarkers for inflammation and oxidative stress in Koreans with and without depression. Study participants comprised 80 cases diagnosed with depression based on […]
Role of cytokines in intervertebral disc degeneration: pain and disc content Risbud MV,et al. Show allJournal Nat Rev Rheumatol. 2013 Oct 29. doi: 10.1038/nrrheum.2013.160. [Epub ahead of print] Affiliation Department of Orthopaedic Surgery, Jefferson Medical College, 1025 Walnut Street, 511 College Building, Philadelphia, PA 19107, USA. Abstract Degeneration of the intervertebral discs (IVDs) is a […]
Nat Rev Rheumatol. 2014 Jan;10(1):44-56. doi: 10.1038/nrrheum.2013.160. Epub 2013 Oct 29. Risbud MV, Shapiro IM. Abstract Degeneration of the intervertebral discs (IVDs) is a major contributor to back, neck and radicular pain. IVD degeneration is characterized by increases in levels of the proinflammatory cytokines TNF, IL-1α, IL-1β, IL-6 and IL-17 secreted by the IVD cells; […]
A Systematic Review and Meta-analysis E.A. Dowlatshahi The British Journal of Dermatology. 2013;169(2):266-282. Abstract Studies investigating systemic inflammation in psoriasis use different serum markers and report discrepant results. We set out to determine whether systemic inflammation is elevated in patients with psoriasis compared with healthy controls, and to measure the extent of this elevation, by […]
Full Story: Endocrinology Today BALTIMORE — Higher concentrations of inflammatory factors were associated with higher risk for hip fracture, according to study results presented here. “Inflammatory burden may be an important biological factor in fracture etiology, particularly for hip fractures, and now we are seeing this consistency across studies,” Kamil E. Barbour, PhD, MPH, MS, […]
Published: Oct 2, 2013 | Updated: Oct 2, 2013 By Nancy Walsh Full Story: http://www.medpagetoday.com/Rheumatology/Arthritis/42007 Action Points Note that this small randomized trial demonstrated that fish oil, in addition to standard therapy, increased the remission rate in new-onset rheumatoid arthritis. Be aware that larger studies in other populations will be needed to validate the use […]
Manfred Lamprecht, PhD, PhD Adj. Professor Centre for Physiological Medicine Medical University of Graz Harrachgasse 21/II 8010 Graz, AUSTRIA +436641555528 / +433163809610 (FAX) manfred.lamprecht@medunigraz.at / www.medunigraz.at “Probiotic Supplementation Affects Markers of Intestinal Barrier, Oxidation, and Inflammation in Trained Men; A Randomized, Double-Blinded, Placebo-Controlled Trial,” J Int Soc Sports Nutr, 2012 Sep 20; 9(1):45. 49368 (11/2012) […]
Mediators of Inflammation Volume 12 (2003), Issue 2, Pages 59-69 http://dx.doi.org/10.1080/0962935031000114943 Freek J. Zijlstra Abstract Acupuncture has a beneficial effect when treating many diseases and painful conditions, and therefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory […]