Knee Osteoarthritis

Effectiveness of Weight Loss Interventions for Reducing Pain and Disability in People With Common Musculoskeletal Disorders: A Systematic Review With Meta-Analysis

Journal of Orthopaedic & Sports Physical Therapy Published Online:April 9, 2020 Volume0 Issue0 Pages1-55 https://www.jospt.org/doi/10.2519/jospt.2020.9041 Abstract Objective To assess the effectiveness of weight loss interventions on pain and disability in people with knee and hip osteoarthritis (OA) and spinal pain. Design Intervention systematic review. Literature Search Eight online databases and clinical trial registries. Study Selection […]

Sharon Kolasinski, MD, on the New Osteoarthritis Guideline for Hands, Hips, Knees

— Panel leader talks exercise, supplements, “mind-body interventions by Scott Harris, Contributing Writer, MedPage Today March 24, 2020 This article is a collaboration between MedPage Today and: Sharon Kolasinski, MD, is a rheumatologist with Penn Medicine and the University of Pennsylvania School of Medicine. She recently led the panel that developed the 2019 American College […]

Diabetes in Osteoarthritis: Pain Is Worse

— Association was independent of obesity and radiographic severity by Nancy Walsh, Senior Staff Writer, MedPage Today March 3, 2020 Among patients with knee osteoarthritis (OA), pain was greater for those with coexisting diabetes mellitus (DM), and this association was independent of obesity and radiographic severity, European researchers found. In an analysis that adjusted for […]

Cigarette smoking and knee osteoarthritis in the elderly: Data from the Korean National Health and Nutritional Examination Survey

Experimental Gerontology — Kwon HM, et al. | February 28, 2020 Researchers performed this study with 5,117 individuals aged > 60 years, to assess the link between smoking and knee osteoarthritis (OA) in the elderly. The participants were selected from the Korean National Health and Nutritional Examination Survey (KNHANES-VI) 2013–2015, and included those who responded […]

Efficacy of Continuous and Pulsed Therapeutic Ultrasound Combined With Exercises for Knee Osteoarthritis: A Randomized Controlled Trial

Clin Rehabil , 269215520903786 2020 Feb 17 Patrícia Pereira Alfredo Abstract Objectives: To compare the effects of continuous and pulsed therapeutic ultrasound combined with strengthening exercises. Design: This is a double-blind randomized controlled trial. Setting: Pontifical Catholic University. Subjects: One hundred participants with Grade 2-4 knee osteoarthritis and both genders were involved. Intervention: Participants were randomized […]

Mediterranean diet and knee osteoarthritis outcomes: A longitudinal cohort study

Clinical Nutrition Volume 38, Issue 6, December 2019, Pages 2735-2739 NicolaVeronese Summary Objectives Mediterranean diet has several beneficial effects on health, but data regarding the association between Mediterranean diet and knee osteoarthritis (OA) are limited mainly to cross-sectional studies. We investigated whether higher Mediterranean diet adherence is prospectively associated with lower risk of radiographic OA […]

Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: Systematic review and meta-analysis of randomised placebo-controlled trials

BMJ Open — Stausholm MB, Naterstad IF, Joensen J, et al. | November 04, 2019 Since low-level laser therapy (LLLT) is not recommended in major knee osteoarthritis (KOA) treatment guidelines, researchers conducted this systematic review and meta-analysis to ascertain if an LLLT dose-response link exists in KOA. Twenty-two trials (n = 1,063) were meta-analysed. The […]

Cross-sectional analysis of self-reported sedentary behaviors and chronic knee pain among South Korean adults over 50 years of age in KNHANES 2013-2015

BMC Public Health — Lee SH, et al. | November 04, 2019 Researchers conducted this cross-sectional study to explore the connection between sedentary behavior and chronic knee pain in a study population representative of the general Korean population aged > 50 years while also considering the physical activity or BMI. In this investigation, data from Korea’s 6th […]

Comorbidities in Patients With End-Stage Knee OA: Prevalence and Effect on Physical Function

Archuves of Physical Medicine and Rehabilitation November 2019 Volume 100, Issue 11, Pages 2063–2070 Abstract Objective To investigate the prevalence of comorbidities and their effect on physical function, quality of life (QOL), and pain, in patients with end-stage knee osteoarthritis (OA). Design A cross-sectional study. Setting A rehabilitation facility at university hospital. Participants Patients (N=577; […]

Effects of Knee Osteoarthritis on Hip and Ankle Gait Mechanics – Full Text Article

Advances in Orthopedics Volume 2019, Article ID 9757369, 6 pages https://doi.org/10.1155/2019/9757369 Du Hyun Ro Abstract Introduction. Knee osteoarthritis (OA) can affect the hip and ankle joints, as these three joints operate as a kinetic/kinematic chain while walking. Purpose. This study was performed to compare (1) hip and ankle joint gait mechanics between knee OA and […]

Prevalence of knee osteoarthritis features on magnetic resonance imaging in asymptomatic uninjured adults: a systematic review and meta-analysis

British Journal of Sports Medicine Volume 53, Issue 20 Adam G Culvenor Abstract Background Knee MRI is increasingly used to inform clinical management. Features associated with osteoarthritis are often present in asymptomatic uninjured knees; however, the estimated prevalence varies substantially between studies. We performed a systematic review with meta-analysis to provide summary estimates of the prevalence […]

A Randomized Controlled Trial on the Effects of Low-Dose Extracorporeal Shockwave Therapy in Patients With Knee Osteoarthritis

Archives of Physical Medicine and Rehabilitation September 2019 Volume 100, Issue 9, Pages 1695–1702 Abstract Objective To test the efficacy of low-dose extracorporeal shockwave therapy (ESWT) on osteoarthritis knee pain, lower limb function, and cartilage alteration for patients with knee osteoarthritis. Design Randomized controlled trial with placebo control. Setting Outpatient physical therapy clinics within a […]

Early Intervention in Osteoarthritis Has Potential to Help Control Pain and Disability, Reduce Work Loss

06.13.2019 by Julie Maurer Contributing Writer, MedPage Today When a patient is diagnosed with osteoarthritis (OA), his or her first instincts might be to reach for their medicine cabinet or wonder if surgery is in their future, but researchers say that early intervention with exercise and education is important. Canadian researchers have published a study about possible […]

Largest Study Yet Links Obesity to Knee Osteoarthritis

Research should now focus on the role of inflammation in the two conditions, experts say by Scott Harris Contributing Writer, MedPage Today 05.30.2019 A new study provides evidence linking obesity with knee osteoarthritis. With obesity and knee-replacement surgery rates both continuing to rise, experts called for deeper dives into the underlying mechanisms through which obesity […]

Effects of Physical Activity in Knee and Hip Osteoarthritis: A Systematic Umbrella Review.

Med Sci Sports Exerc. 2019 Jun;51(6):1324-1339. doi: 10.1249/MSS.0000000000001944. Kraus VB Abstract INTRODUCTION: We conducted a systematic umbrella review to evaluate the literature relating to effects of physical activity on pain, physical function, health-related quality of life, comorbid conditions and osteoarthritis (OA) structural disease progression in individuals with lower-extremity OA. METHODS: Our primary search encompassed 2011 […]

Proprioceptive Training and Outcomes of Patients With Knee Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials

J Athl Train. 2019 Apr;54(4):418-428. doi: 10.4085/1062-6050-329-17. Epub 2019 Apr 17. Proprioceptive Training and Outcomes of Patients With Knee Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. Jeong HS. Abstract OBJECTIVE: To describe the effects of proprioceptive training on pain, stiffness, function, and functional test outcomes among patients with knee osteoarthritis (OA). DATA SOURCES: All studies […]

Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization

Evid Based Complement Alternat Med. 2019 Mar 7;2019:6173412. doi: 10.1155/2019/6173412. eCollection 2019. Lai HC Abstract Pain can trigger central amplification called central sensitization, which ultimately results in hyperalgesia and/or allodynia. Many reports have showed acupuncture has an analgesic effect. We searched the related article on PubMed database and Cochrane database to discover central sensitization pathway […]

Knee Arthritis Pain Relief Peaks Early With Non-Steroidal Anti-inflammatory Drugs

Don’t expect relief to last beyond a few months by Nancy Walsh, Senior Staff Writer, MedPage Today March 29, 2019 Pain relief from nonsteroidal anti-inflammatory drugs (NSAIDs) in knee osteoarthritis (OA) was rapid but declined over time, a large meta-analysis demonstrated. Data from 72 randomized controlled trials found that statistically significant reductions in pain peaked […]

Two Knees at Once: More Clarity on Pluses and Minuses

Surgeons say it’s feasible in even severely obese patients, but beware of complications by Randy Dotinga, Contributing Writer, MedPage Today March 19, 2019 LAS VEGAS — Simultaneous bilateral total knee arthroplasty (SBTKA) is a feasible option for many patients, including those who are severely obese, according to authors of a pair of new studies that […]

Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation.

Osteoarthritis Cartilage. 2019 Jul;27(7):1064-1074. doi: 10.1016/j.joca.2019.03.003. Epub 2019 Mar 25. Fu S, Thompson C2, Ali A, Wang W, Chapple JP, Mitchison HM, Beales PL, Wann AKT, Knight MM. Abstract OBJECTIVE: Physiological mechanical loading reduces inflammatory signalling in numerous cell types including articular chondrocytes however the mechanism responsible remains unclear. This study investigates the role of […]