Gastrointestinal System

Symptomatic improvement with gluten restriction in irritable bowel syndrome: a prospective, randomized, double blinded placebo controlled trial

Intest Res. 2016 Oct; 14(4): 343–350. Published online 2016 Oct 17. doi:  10.5217/ir.2016.14.4.343 PMCID: PMC5083263 Vinay G Zanwar, Sunil V Pawar, Pravir A Gambhire, Samit S Jain, Ravindra G Surude, Vinaya B Shah, Qais Q Contractor, and Pravin M Rathi Author information ► Article notes ► Copyright and License information ► Abstract Background/Aims The existence […]

Probiotics and Prebiotics Alleviate Constipation in Parkinson’s Disease

October 12, 2016 TAKE-HOME MESSAGE “Constipation is extremely common in Parkinson’s disease, and quite difficult to manage, particularly in late disease stages. Disruption in the intestinal biostasis has been shown in Parkinson’s disease, and, based on these findings, as well as smaller prior attempts, the authors conducted a randomized, parallel-group, double-blind, placebo-controlled clinical trial of […]

High Glycemic Index Diet Raises Hepatic Fat, Glycogen Stores

One-week high GI diet increases hepatic fat and glycogen stores compared with low GI diet   FRIDAY, Sept. 9, 2016 (HealthDay News) — A one-week high glycemic index (HGI) diet increases hepatic fat and glycogen stores in healthy adults compared with a low glycemic index (LGI) diet, according to a study published online Sept. 4 […]

Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease

Gut doi:10.1136/gutjnl-2016-311964 Melanie Uhde Abstract Objective Wheat gluten and related proteins can trigger an autoimmune enteropathy, known as coeliac disease, in people with genetic susceptibility. However, some individuals experience a range of symptoms in response to wheat ingestion, without the characteristic serological or histological evidence of coeliac disease. The aetiology and mechanism of these symptoms […]

Persistent Nonalcoholic Fatty Liver Disease Increases Risk for Carotid Atherosclerosis

July 06, 2016 Gastroenterology TAKE-HOME MESSAGE The authors of this retrospective, cohort study evaluated the association between nonalcoholic fatty liver disease (NAFLD) and subsequent development of subclinical carotid atherosclerosis in 8020 men. They found that, compared with men without NAFLD, men with persistent NAFLD had significantly greater risk of incident subclinical carotid atherosclerosis (HR, 1.23; […]

PPI Use Ups NSAID-Induced Small Bowel Injury

May 30, 2016 Increased risk of small bowel injury for healthy participants treated with celecoxib + PPI HealthDay FRIDAY, May 27, 2016 (HealthDay News) — Proton pump inhibitors (PPIs) increase the risk of nonsteroidal anti-inflammatory drug-induced small bowel injury, according to a study published in the June issue of Clinical Gastroenterology and Hepatology. Ema Washio, […]

Feeding at the Breast and Expressed Milk Feeding: Associations With Otitis Media and Diarrhea in Infants

5/31/16 The Journal of Pediatrics TAKE-HOME MESSAGE Women completed a questionnaire 12 months post delivery to evaluate the association between substance and mode of infant feeding with risk of infant otitis media and diarrhea during the first year of life. The risk of otitis media in infants fed only breast milk was highest in children […]

Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients

Neurogastroenterol Motil. 2016 May 7. doi: 10.1111/nmo.12851. [Epub ahead of print] Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial. Abbasnezhad A, Amani R, Hajiani E, Alavinejad P, Cheraghian B, Ghadiri A. Abstract BACKGROUND: Low-grade mucosal inflammation and immune activation are involved […]

Functions of Coenzyme Q10 Supplementation on Liver Enzymes, Markers of Systemic Inflammation, and Adipokines in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial.

J Am Coll Nutr. 2016 May-Jun;35(4):346-53. doi: 10.1080/07315724.2015.1021057. Epub 2015 Jul 9. Farsi F1, Mohammadshahi M1, Alavinejad P2, Rezazadeh A3, Zarei M4, Engali KA5. Abstract BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disorder related to inflammation. Coenzyme Q10 (CoQ10) is a natural compound that has recently been considered as an anti-inflammatory factor. […]

Celiac Disease and Risk of Autoimmune Disorders

April 12, 2016 The Journal of Pediatrics TAKE-HOME MESSAGE Children with celiac disease (CD) were matched with healthy controls to evaluate the relative risk of type 1 diabetes mellitus (T1DM) and autoimmune thyroid disease. Children with CD were at significantly increased risk of developing hypothyroidism compared with controls (HR 4.64). There was also an increased […]

Association Between Psoriasis and Inflammatory Bowel Disease

March 25, 2016 The British Journal of Dermatology TAKE-HOME MESSAGE The association between psoriasis and inflammatory bowel disease (IBD) was studied in this nationwide Danish cohort trial. Investigators found that the risk of IBD increased as psoriasis disease severity increased. The adjusted incidence rate ratios (IRRs) of ulcerative colitis were 1.49, 1.56, 1.96, and 2.43 […]

Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants

March 4, 2016 Michael R. Perkin, Ph.D. BACKGROUND The age at which allergenic foods should be introduced into the diet of breast-fed infants is uncertain. We evaluated whether the early introduction of allergenic foods in the diet of breast-fed infants would protect against the development of food allergy. METHODS We recruited, from the general population, […]

New Position Paper Developed for Introduction of Gluten in Infancy

Gluten may be introduced between 4 and 12 months; earlier introduction tied to earlier development of CD MONDAY, Jan. 25, 2016 (HealthDay News) — New recommendations, published online Jan. 13 in the Journal of Pediatric Gastroenterology and Nutrition, have been issued for the introduction of gluten in infants. Hania Szajewska, M.D., Ph.D., from the Medical […]

The neurons in our gut help the immune system keep inflammation in check

Date: January 22, 2016 Source: Rockefeller University Summary: The immune system must protect against potential infections, but over-vigilant reactions can cause problems. New research shows that neurons in the intestine send signals to immune cells to curb inflammation. The immune system exercises constant vigilance to protect the body from external threats–including what we eat and […]

Asthma – An Epidemic Explained

DAVIDPERLMUTTER So much has been written in scientific journals recently about how the loss of microbes in the gut, especially earlier in life, affects the immune system. For example, researcher Marsha Wills-Karp, at the Johns Hopkins School of Public Health, recently revealed how early life exposure to antibiotics is associated with a substantial increased risk […]

Meditation: how could it benefit your health?

Written by Honor Whiteman Published: Sunday 27 December 2015 For many people, the word “meditation” is likely to evoke images of a cross-legged individual, eyes closed, humming to themselves, but there is so much more to the practice than meets the eye. Meditation is an ancient mind and body practice that is estimated to date […]

National Center for Complementary and Integrative Health: Peppermint Oil

Common Name: peppermint oil Latin Name:  Mentha x piperita Introduction This fact sheet provides basic information about peppermint oil—common names, what the science says, potential side effects and cautions, and resources for more information. The herb peppermint, a cross between two types of mint (water mint and spearmint), grows throughout Europe and North America. Peppermint is often used to […]

Vitamin E May Benefit NASH Patients

11.18.2015 Pooled analysis: Improvements in liver histology, but no NASH resolution by Kristina Fiore Staff Writer, MedPage Today SAN FRANCISCO — Vitamin E was associated with improvement in liver histology in non-alcoholic steatohepatitis (NASH) patients whether or not they had diabetes, researchers reported here. In an analysis that pooled data from two trials, vitamin E […]

Low FODMAP Diet Cuts Irritable Bowel Syndrome Symptoms

Similar reductions for diet with reduced content of fermentable short-chain carbs, traditional advice FRIDAY, Nov. 13, 2015 (HealthDay News) — A diet with reduced content of fermentable short-chain carbohydrates (fermentable oligo-, di-, monosaccharides, and polyols [FODMAPs]) reduces symptoms of irritable bowel syndrome (IBS), with reductions similar to those seen for traditional dietary advice, according to […]

Food Allergy Connected to Irritable Bowel Syndrome

Kate Johnson November 11, 2015 SAN ANTONIO — Food allergy and atopy might be underlying factors in some patients with irritable bowel syndrome (IBS), two new studies suggest. In fact, the constellation of allergic asthma, rhinitis, and eczema in a subgroup of IBS patients goes hand-in-hand with diarrhea and gastrointestinal reactions to food. “The thinking […]