Cardiovascular Risk Factors

Beta-blockers tied to higher stroke risk in some patients

An analysis of data on nearly 15,000 patients found that treatment with beta-blockers was linked to a higher risk of stroke among patients with multiple heart disease risk factors but no history of a cardiovascular event. Researchers also found that use of beta-blockers was not linked to lower cardiovascular events in those with no history […]

Inflammation: Continued Support for a Small Changes Approach

Craig A. Johnston, PhD Am J Lifestyle Med. 2012;6(1):18-20. Story Source ABSTRACT AND INTRODUCTION Abstract Lifestyle interventions show considerable promise in improving levels of inflammation. This review discusses how these improvements in inflammation are consistent with a “small changes” approach. Introduction Managing inflammation has the potential to be a key component in warding off disease. This […]

Effects of Aerobic, Resistance, or Combined Training in Obese Adolescents

Story Source: PracticeUpdate.com RESEARCH · September 22, 2014 TAKE-HOME MESSAGE This randomized clinical trial assessed the effects of various exercise modalities in obese adolescents. For 22 weeks, 304 participants underwent aerobic training, resistance training, combined aerobic and resistance training, or no exercise. Groups undergoing exercise showed a significantly greater decrease in percentage body fat compared […]

The Crystal Ball Heart Test Rarely Tested

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. As a reader of YMD News you have learned that elevated fibrinogen, hsCRP, a CT heart scan and homocysteine are among the many known risk factors for progressive heart disease. It now turns out that there is a blood test that is an even a better indicator than any […]

Kidney Stones May Raise Heart, Stroke Risk

Published: Sep 5, 2014 By Salynn Boyles, Contributing Writer, MedPage Today Action Points In a meta-analysis of cohort studies, a history of kidney stones was associated with an increased adjusted risk estimate for CHD and stroke. The data suggest that the risk may be higher in women than men. Development of kidney stones was associated […]

Low Carb Beats Low Fat for Weight Loss, CV Risk

Published: Sep 1, 2014 | Updated: Sep 2, 2014 By Nancy Walsh, Senior Staff Writer, MedPage Today Reviewed by F. Perry Wilson, MD, MSCE; Assistant Professor, Section of Nephrology, Yale School of Medicine and Dorothy Caputo, MA, BSN, RN, Nurse Planner Story Source Action Points Note that this small randomized trial demonstrated that a low-carbohydrate […]

Unexpected effect of proton pump inhibitors – Full Text

Circulation, 08/20/2013  Exclusive Author Commentary Clinical Article Ghebremariam YT et al. – Proton pump inhibitors (PPIs) are gastric acid–suppressing agents widely prescribed for the treatment of gastroesophageal reflux disease. Recently, several studies in patients with acute coronary syndrome have raised the concern that use of PPIs in these patients may increase their risk of major […]

Latest evidence of the effects of the mediterranean diet in prevention of cardiovascular disease

MDLinx.com Current Atherosclerosis Reports, 08/19/2014 Evidence Based Medicine  Review Article Clinical Article Story Source Chiva–Blanch G, et al. – Recent systematic reviews of observational studies ranked Mediterranean diet as the most likely dietary model to provide cardiovascular protection. These recent results allow us to recommend Mediterranean diet to subjects at high risk for cardiovascular disease […]

Triglycerides and cardiovascular disease

Triglycerides and cardiovascular disease The Lancet, 08/19/2014 Evidence Based Medicine Clinical Article Nordestgaard BG, et al. – After the introduction of statins, clinical emphasis first focussed on LDL cholesterol–lowering, then on the potential for raising HDL cholesterol, with less focus on lowering triglycerides. However, the understanding from genetic studies and negative results from randomised trials […]

Can instant noodles lead to heart disease, diabetes and stroke?

Date:  August 12, 2014 Source:  Baylor Scott & White Health Summary:  Significant consumption of instant noodles — ramen included — may increase a person’s risk for cardiometabolic syndrome, especially in women, research shows. The findings could shed new light on the risks of a worldwide dietary habit. “This research is significant since many people are […]

Can The Shape of Your Earlobe Predict a Heart Attack ?

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. Story Source Most people are very well aware of the correlation of high cholesterol, high blood pressure, obesity, etc.. but ear creases?! To the surprise of many people, Earlobe Creases May Indicate Artery Disease. The possible association between ear lobe creases and coronary artery disease garnered attention when a […]

Leisure-Time Running Reduces All-Cause and Cardiovascular Mortality Risk

August 06, 2014 JACC: Journal of the American College of Cardiology TAKE-HOME MESSAGE The associations between running and all-cause and cardiovascular (CV) mortality risk were examined in 55,137 adults between 18 and 100 years of age. Running was assessed via a medical history questionnaire (leisure-time activity). Mean follow-up time was 15 years. Compared with non-runners, […]

A Very Low Carbohydrate, Low Saturated Fat Diet for Type 2 Diabetes Management: A Randomized Trial

Tay J Diabetes Care. 2014 Jul 28. pii: DC_140845. [Epub ahead of print] Abstract OBJECTIVE: To comprehensively compare the effects of a very low carbohydrate, high unsaturated/low saturated fat diet (LC) to a high-unrefined carbohydrate, low fat diet (HC) on glycemic control and cardiovascular disease (CVD) risk factors in type 2 diabetes (T2DM). RESEARCH DESIGN […]

New Evidence Fuels Concerns About The Safety Of Niacin

Effects of Extended-Release Niacin with Laropiprant in High-Risk Patients The HPS2-THRIVE Collaborative Group N Engl J Med 2014; 371:203-212 July 17, 2014DOI: 10.1056/NEJMoa1300955 BACKGROUND Patients with evidence of vascular disease are at increased risk for subsequent vascular events despite effective use of statins to lower the low-density lipoprotein (LDL) cholesterol level. Niacin lowers the LDL cholesterol […]

Pistachio Nut Consumption Improves Cardiovascular Risk Factors in Diabetes

RESEARCH · July 01, 2014 TAKE-HOME MESSAGE In this randomized, crossover, controlled feeding study, 30 adults with type 2 diabetes mellitus (T2DM) consumed a low-fat control diet with low-fat/high-carbohydrate snacks and a moderate-fat diet containing pistachios (20% of total energy) for 4 weeks each, separated by a 2-week washout. A diet containing pistachios significantly reduced […]

Pregnancy Loss Linked to Later Heart Disease

MedPageToday Published: Jul 15, 2014 By Crystal Phend, Senior Staff Writer, MedPage Today Action Points Miscarriages and stillbirths might be a marker for women at higher risk of developing heart disease later in life. The study suggests that physicians should now include stillbirth or miscarriage on their list of items to ask about in screening […]

HbA1c – A Modifiable Predictor of Heart Disease

YourHealthDetective.com Researchers at the Johns Hopkins Bloomberg School of Public Health believe that lowering blood glucose levels could reduce the risk of coronary heart disease in both diabetics and non-diabetics. The researchers found that hemoglobin A1c ( HbA1c ) — a measure of long-term blood glucose level — predicts heart disease risk in both diabetics and non-diabetics. […]

Association between class III obesity (BMI of 40-59 kg/m2) and mortality – Full Text

Association between class III obesity (BMI of 40-59 kg/m2) and mortality: a pooled analysis of 20 prospective studies Full Text PLoS Medicine, 07/14/2014  Evidence Based Medicine Clinical Article Kitahara CM, et al. – The prevalence of class III obesity (body mass index [BMI]>=40 kg/m2) has increased dramatically in several countries and currently affects 6% of […]

Nonfasting and Fasting LDL Equally Predict Mortality in NHANES Analysis

Michael O’Riordan July 11, 2014 NEW YORK, NY — Do patients need to fast before having their cholesterol levels measured? A new analysis suggests maybe not, with researchers reporting that nonfasting LDL-cholesterol levels provide equivalent prognostic value to fasting LDL-cholesterol levels. Using data from the National Health and Nutrition Survey III(NHANES III), lead investigator Dr Bethany Doran (New […]

Weak Bones Tied to Incident HF

MedPageToday Cardiovascular Published: Jul 10, 2014 By Todd Neale, Senior Staff Writer, MedPage Today Story Source Action Points Note that this observational cohort study demonstrated an association between lower bone mineral density in the heel and incident heart failure. Be aware that calcaneal ultrasound is not the standard tool for diagnosing osteoporosis; DXA scanning or, […]