Long-term, systemic antibiotic use for the treatment of adolescent acne can promote fat accumulation Published March 14, 2023 | Originally published on MedicalXpress Breaking News-and-Events A growing body of evidence is showing that the healthy gut microbiome—a community of microorganisms that live together in the gut—influences many aspects of human growth and development, especially during […]
February 27, 2023 Risk for all-cause, vascular dementia was increased with number of regularly used laxative types THURSDAY, Feb. 23, 2023 (HealthDay News) — Regular use of laxatives, especially use of multiple laxative types, is associated with an increased risk for all-cause dementia, according to a study published online Feb. 22 in Neurology. Zhirong Yang, […]
September 14, 2022 The Lancet TAKE-HOME MESSAGE This large meta-analysis investigated the effects of statins on muscle symptoms over time based on data from 154,664 participants in 23 double-blind trials. The relative increase of muscle pain or weakness was <10% (1 in 15 patients), mainly during the first year of statin use. It also confirmed […]
By Joe Hannan | Medically reviewed by Amanda Zeglis, DO, MBA | Published August 17, 2022 Key Takeaways A 2022 study found that long-term cannabis users had cognitive deficits and lower hippocampal volume at age 45 compared with non-users and users of other substances. Legalization and decriminalization efforts, coupled with medical marijuana programs, may be […]
Regular Acetaminophen Use and Blood Pressure in People With Hypertension: The PATH-BP Trial Iain M. MacIntyre, Emma J. Turtle, Tariq E. Farrah, Catriona Graham, James W. Dear and David J. Webb and for the PATH-BP (Paracetamol in Hypertension–Blood Pressure) Investigators* Originally published 7 Feb 2022https://doi.org/10.1161/CIRCULATIONAHA.121.056015Circulation. 2022;145:416–423 Abstract Background: Acetaminophen is widely used as first-line therapy […]
— Better efficacy and no pricier over time by John Gever, Contributing Writer, MedPage Today January 24, 2022 Although physical therapy for osteoarthritis of the knee costs more than an intra-articular steroid injection, it’s cost-effective when clinical outcomes a year later are taken into account, researchers said. A secondary analysis of data from 156 participants […]
November 10, 2021 JAMA Network Open TAKE-HOME MESSAGE This follow-up to a double-blind, placebo-controlled RCT sought to explore whether local steroid injection (with 80 mg or 40 mg of methylprednisolone) versus saline impacted long-term carpal tunnel pain scores and rates of carpal tunnel release surgery, as well as other outcomes such as time to surgery. The […]
November 07, 2021 BMJ : British Medical Journal TAKE-HOME MESSAGE This comprehensive systematic review and network meta-analysis assesses the efficacy and safety of multiple preparations and doses of NSAIDs, opioids, and acetaminophen for clinically relevant reductions in pain caused by knee and hip osteoarthritis. The review includes nearly 200 randomized controlled trials comprised of over 100,000 […]
Newswise: Respiratory Diseases and Disorders | October 15, 2021 It may be worth exploring further the use of cannabidiol (‘CBD’) oil as a potential lung cancer treatment, suggest doctors in BMJ Case Reports after dealing with a daily user whose lung tumour shrank without the aid of conventional treatment. The body’s own endocannabinoids are involved […]
Kanae Togo PhD,Nozomi Ebata PhD,Naohiro Yonemoto PhD,Lucy Abraham MSc CPsychol, First published: 19 September 2021 https://doi.org/10.1111/papr.13079 Abstract Purpose This study aimed to assess the safety risks associated with using nonsteroidal anti-inflammatory drugs (NSAIDs) in elderly patients (≥65 years) compared with younger patients (<65 years) with osteoarthritis (OA) and/or chronic low back pain (CLBP). Methods A retrospective analysis […]
The Science of Pain-Killers A user’s guide to over-the-counter analgesics like acetaminophen, ibuprofen, and more Paul Ingraham • Jun 30, 2021 • 15m read Ordinary pain-killers like ibuprofen and acetaminophen are fairly safe and somewhat effective in moderation and work in different ways, so cautious experimentation is justified for many people. They are all roughly […]
Date: April 25, 2021 Source: Syracuse University Summary: In an experimental pain study of CBD in humans, researchers conclude that CBD pain relief is driven by both pharmacological action and psychological placebo effects. It’s been hailed as a wonder drug and it’s certainly creating wonder profits. By some estimates, the Cannabidiol (or CBD) market could […]
Reuters Health Medical News|April 13, 2021 Thiazide diuretics, which are used by many older patients to control blood pressure, are linked to increased risk of certain skin cancers in a new Canadian study. The analysis of data from more than 300,000 Ontario adults aged 66 and older revealed that prolonged use of thiazides, including hydrochlorothiazide, […]
Luepker RV, Oldenburg NC, Misialek JR, et al American Journal of Preventive Medicine | February 4, 2021 This study was sought to present the prevalence of appropriate aspirin use and physician advice in a population sample using the Task Force recommendations. Between 2017 and 2018, a random sample of men and women (aged 50–69 years) […]
Naveed Saleh, MD, MS | January 8, 2021 In recent years, the gut microbiome has received much attention. The microbiota plays an important role in health and pathology. Hard-to-treat nosocomial infections in hospitalized patients, for instance, often derive from the microbiome, where antibiotic use selects for antibiotic-resistant organisms. Antibiotic use should always be carefully considered, […]