Hematologic and Lymphatic

Unexpected effect of proton pump inhibitors – Full Text

Circulation, 08/20/2013  Exclusive Author Commentary Clinical Article Ghebremariam YT et al. – Proton pump inhibitors (PPIs) are gastric acid–suppressing agents widely prescribed for the treatment of gastroesophageal reflux disease. Recently, several studies in patients with acute coronary syndrome have raised the concern that use of PPIs in these patients may increase their risk of major […]

Low albumin to globulin ratio associated with cancer incidence and mortality in generally healthy adults

Annals of Oncology, 08/04/2014 Clinical Article Suh B, et al. – This study suggest that low AGR is a risk factor for cancer incidence and mortality, both short–term and long–term, in a generally healthy screened population. The results of this study need to be replicated in larger studies, along with the determination of the sensitivity […]

Serology Markers for Mucosal Recovery in Children With Celiac Disease on a Gluten-Free Diet

PracticeUpdate.com July 29, 2014 TAKE-HOME MESSAGE This prospective study evaluated the sensitivity and specificity of the serological markers anti-tissue transglutaminase immunoglobulin and anti-deamidated gliadin peptide antibodies for assessing mucosal recovery in children with celiac disease on a gluten-free diet. Duodenal biopsies and serology were taken before and 12 months after starting the diet in 150 […]

High Urate? Get Moving, Study Finds

Regular exercise significantly lessened the excess mortality risk associated with elevated serum uric acid, a large Taiwanese study found. by Nancy Walsh, Senior Staff Writer, MedPage Today July 25, 2014 Action Points Regular exercise significantly lessened the excess mortality risk associated with elevated serum uric acid, a large Taiwanese study found. Among individuals whose serum […]

CoQ10 Reduces Serum Gamma Glutamyl Transpeptidase (GGT)

Reference: “Ubiquinol (Q10H2) reduces gamma glutamyltransferase (GGT) as a marker of oxidative stress in humans,” Onur S, Niklowitz P, et al, BMC Res Notes 2014 Jul 4; 7(1): 427. (Address: Institute of Human Nutrition and Food Science, Division of Molecular Prevention, Christian Albrechts University Kiel, Heinrich-Hecht-Platz 10, 24118 Kiel, Germany. E-mail: sek@molprev.uni-kiel.de ). Summary: In […]

Biomarker Panel Identified Patients With Pancreatic Cancer

Frontline Medical News, 2014 May 20, A Karon Full Story A biomarker panel distinguished individuals with pancreatic cancer from those who were healthy, had benign pancreatic cysts, or had chronic pancreatitis with about 90% accuracy, based on analyses of two cohorts. The panel, which tests for the known pancreatic cancer biomarker CA 19-9 plus three […]

Uric Acid Linked to Fracture Risk

 — Older men with higher uric acid levels may be at increased risk for hip fracture, researchers reported here. by Kristina Fiore, Staff Writer, MedPage Today April 28, 2014 AS VEGAS — Older men with higher uric acid levels may be at increased risk for hip fracture, researchers reported here. In a prospective cohort study, […]

Risk Score Predicts Arthritis Progression

Published: Apr 19, 2014 By Nancy Walsh, Senior Staff Writer, MedPage Today Action Points A risk score encompassing clinical characteristics, serologic findings, and imaging tests could be used to predict which patients with positive antibodies to anti-cyclic citrullinated peptide are likely to go on to develop rheumatoid arthritis (RA), researchers found. Note that in the […]

Weight Loss Improves Iron Status and Inflammatory Markers in Obese Children

Weight Loss, Inflammation, and Iron Status in Overweight and Obese Children J Pediatr 2014 Feb 08;[EPub Ahead of Print], L Gong, F Yuan, J Teng, X Li, S Zheng, L Lin, H Deng, G Ma, C Sun, Y Li Research · February 25, 2014  Full Story Journal Reference TAKE-HOME MESSAGE Results of this study looking at iron […]

B12 Deficiency Tied to Reflux Medications

Published: Dec 11, 2013 By Cole Petrochko, Staff Writer, MedPage Today Full Story:  http://www.medpagetoday.com/Endocrinology/GeneralEndocrinology/43363 Vitamin B12 deficiency is significantly more likely among patients taking prescription medications for gastroesophageal reflux disease (GERD), researchers found. Taking either a proton pump inhibitor or a histamine 2 receptor antagonist over 2 years was associated with a greater risk for […]

Fructose, Uric Acid Culprits in Diabetes, Obesity

12.21.2013 by Elbert Chu Associate Producer, MedPage Today Recent research in metabolism implicates fructose as a more dangerous culprit in metabolic diseases than other forms of sugar. To catch up on the latest findings in ongoing research, we talked with Richard J. Johnson, MD, chief of the Division of Renal Diseases and Hypertension at the […]

Determinants of RBC omega-3 fatty acid content in response to fish oil supplementation

A dose-response randomized controlled trial Flock MR, Skulas-Ray AC, et al J Am Heart Assoc, 2013 Nov 19; 2(6):e000513. Abstract Background The erythrocyte membrane content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which constitutes the omega‐3 index (O3I), predicts cardiovascular disease mortality. The amount of EPA+DHA needed to achieve a target O3I is poorly defined, as […]

Men (Aged 40-49 Years) With a Single Baseline PSA Below 1.0 ng/mL Have a Very Low Long-Term Risk of Prostate Cancer

Results From a Prospectively Screened Population Cohort Urology 2013 Oct 21;[EPub Ahead of Print], CJ Weight, SP Kim, DJ Jacobson, ME McGree, RJ Karnes, J St Sauver TAKE-HOME MESSAGE In men undergoing screening as part of a prospectively followed population cohort, a single baseline PSA test < 1.0 ng/mL predicted for a very low long-term risk of […]

Mediterranean Diet May Protect Kidneys

Published: Nov 8, 2013 | Updated: Nov 8, 2013 By Kristina Fiore, Staff Writer, MedPage Today Full Story:  http://www.medpagetoday.com/MeetingCoverage/ASN/42800 Action Points Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. In this prospective, observational […]

The Power of Vitamin K

Evidence suggests a role in cancer prevention, cardiovascular health and bone mineralization. By James P. Meschino, DC, MS Dynamic Chiropractic – November 1, 2013, Vol. 31, Issue 21 You may have heard rumblings in recent years that vitamin K helps reduce the risk of osteoporosis and cardiovascular disease, and is administered intravenously by some integrative medical doctors who […]

Food Allergy Overdiagnosed With IgE Tests Frontline Medical News, 2014 May 13, S Boschert PracticeUpdate.com SAN DIEGO (FRONTLINE MEDICAL NEWS) – Unwarranted food allergy testing in 67% of 274 patients who underwent testing identified a new food allergen in only 4 patients, in a retrospective study. The review of charts on patients referred to a […]

Your Doctor May Be Misleading You About Your Lab Results and Whats ‘Normal’

J.D. Heyes Natural News May 3, 2013 Story Source Most Americans have little-to-no medical training whatsoever, so it’s nigh-on impossible for them to figure out what is and is not “normal,” in terms of lab results and so forth. What’s more, your doctor may not be providing you with complete information either, regarding what is […]

PSA Screening’s Harms Outweigh Benefits

PracticeUpdate.com ACP: PSA Screening’s Harms Outweigh Benefits Frontline Medical News, 2013 Apr 08, MA Otto Story Source Expert Comment Primary Care David Rakel MD, FAAFP To Order or Not to Order, Is That the Question? The American College of Physicians reviewed the guidelines from the USPSTF, AUA, ACS, and ACPM and made the following recommendations […]